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Peptoids for Biomimetic Hierarchical Structures

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Book cover Hierarchical Macromolecular Structures: 60 Years after the Staudinger Nobel Prize II

Part of the book series: Advances in Polymer Science ((POLYMER,volume 262))

Abstract

Life as we know it is impossible without formation of hierarchical structures. First and foremost, proteins, that is, sequence-specific polypeptides, are nature′s vanguard in this respect. Peptoids and polypeptoids are structural isomers and analogs to peptides and polypeptides. Here, we review the advancements over the last few years on biomimetic hierarchical structures obtained using polypeptoids. Although the inherently more flexible amide bond in peptoids make the stabilization of secondary structure challenging, it also gives us a tool to direct the conformation of the amide bond by design. As will be seen, this is a particularly important feature of peptoids.

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Acknowledgement

We gratefully acknowledge financial support from the German Plastics Center SKZ and the Universität Würzburg for start-up funding.

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Authors and Affiliations

  1. Functional Polymer Materials, Chair of Chemical Technology of Materials Synthesis, University Würzburg, Röntgenring 11, 97070, Würzburg, Germany

    Niklas Gangloff & Robert Luxenhofer

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  1. Niklas Gangloff
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  2. Robert Luxenhofer
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Correspondence to Robert Luxenhofer .

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Editors and Affiliations

  1. Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Virgil Percec

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Gangloff, N., Luxenhofer, R. (2013). Peptoids for Biomimetic Hierarchical Structures. In: Percec, V. (eds) Hierarchical Macromolecular Structures: 60 Years after the Staudinger Nobel Prize II. Advances in Polymer Science, vol 262. Springer, Cham. https://doi.org/10.1007/12_2013_237

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