Abstract
Stimuli-responsive macromolecules (i.e., pH-, thermo-, photo-, chemo-, and bioresponsive polymers) have gained exponential importance in materials science, nanotechnology, and biotechnology during the last two decades. This chapter describes the usefulness of this class of polymer for preparing smart surfaces (e.g., modified planar surfaces, particles surfaces, and surfaces of three-dimensional scaffolds). Some efficient pathways for connecting these macromolecules to inorganic, polymer, or biological substrates are described. In addition, some emerging bioapplications of smart polymer surfaces (e.g., antifouling surfaces, cell engineering, protein chromatography, tissue engineering, biochips, and bioassays) are critically discussed.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Gil ES, Hudson SM (2004) Prog Polym Sci 29:1173–1222
Cohen Stuart MA et al. (2010) Nat Mater 9:101–113
de las Heras Alarcón C, Pennadam S, Alexander C (2005) Chem Soc Rev:276–285
Wischerhoff E et al (2009) Soft Matter 6:705–713
Mendes PM (2008) Chem Soc Rev 37:2512–2529
Sun A, Lahann J (2009) Soft Matter 5:1555–1561
Motornov M et al (2010) Prog Polym Sci 35:174–211
Shanmuganathan K et al (2010) Prog Polym Sci 35:212–222
Roy D, Cambre JN, Sumerlin BS (2010) Prog Polym Sci 35:278–301
Lutz J-F (2006) Polym Int 55:979–993
Martin GR, Jain RK (1994) Cancer Res 54:5670–5674
Willerson JT, Ridker PM (2004) Circulation 109:II-2–II-10
Berndt E, Ulbricht M (2009) Polymer 50:5181–5191
de las Heras Alarcón C et al (2005) J Mater Chem 15:2089–2094
Kaholek M et al (2004) Nano Lett 4:373–376
Matsuda N et al (2007) Adv Mater 19:3089–3099
Mizutani A et al (2008) Biomaterials 29:2073–2081
Ernst O et al (2008) Langmuir 24:10259–10264
Zhou F, Huck WTS (2006) Phys Chem Chem Phys 8:3815–3823
Kanazawa H et al (2008) J Chromatogr A 1191:157–161
Nagase K et al (2007) Langmuir 23:9409–9415
Sun T et al (2004) Angew Chem Int Ed 43:357–360
Okano T et al (1993) J Biomed Mater Res 27:1243–1251
Wei Q, Ji J, Shen J (2008) Macromol Rapid Commun 29:645–650
Wischerhoff E et al (2000) Angew Chem Int Ed 39:4602–4604
Heinz BS et al (2001) Grafting of functionalized water soluble polymers on gold surfaces. In: McCormick CL (ed) Stimuli-responsive water soluble and amphiphilic polymers. ACS symposium series, vol 780. ACS, Washington DC, p 162
Jeong B, Kim SW, Bae YH (2002) Adv Drug Deliv Rev 54:37–51
Xu C et al (2006) Nano Lett 6:282–287
Lequieu W, Shtanko NI, Du Prez FE (2005) J Membr Sci 256:64–71
Meyer DE, Chilkoti A (2004) Biomacromolecules 5:846–851
Fernández-Trillo F et al (2009) Adv Mater 21:55–59
Hyun J et al (2004) J Am Chem Soc 126:7330–7335
Han S, Hagiwara M, Ishizone T (2003) Macromolecules 26:8312–8319
Ali MM, Stöver HDH (2004) Macromolecules 37:5219–5227
Yamamoto S-I, Pietrasik J, Matyjaszewski K (2007) Macromolecules 40:9348–9353
Lutz J-F, Akdemir Ö, Hoth A (2006) J Am Chem Soc 128:13046–13047
Lutz J-F, Hoth A (2006) Macromolecules 39:893–896
Lutz J-F et al (2007) Macromolecules 40:8540–8543
Lutz J-F et al (2007) Macromolecules 40:2503–2508
Lutz J-F (2008) J Polym Sci A Polym Chem 46:3459–3470
Lutz J-F, Hoth A, Schade K (2009) Des Monomers Polym 12:343–353
Becer CR et al (2008) J Polym Sci A Polym Chem 46:7138–7147
Holder SJ et al (2008) J Polym Sci A Polym Chem 46:7739–7756
Wischerhoff E et al (2009) Langmuir 25:5949–5956
Wischerhoff E et al (2008) Angew Chem Int Ed 47:5666–5668
Fechler N et al (2009) Macromolecules 42:33–36
Badi N, Lutz J-F (2009) J Control Release 140:224–229
Kessel S et al (2010) Langmuir 26:3462–3467
Dai S, Ravi P, Tam KC (2008) Soft Matter 4:435–449
Argentiere S et al (2009) Soft Matter 5:4101–4103
Ayres N, Boyes SG, Brittain WJ (2007) Langmuir 23:182–189
Yamamoto S-I, Pietrasik J, Matyjaszewski K (2008) Macromolecules 41:7013–7020
Van Camp W et al (2010) Eur Polym J 46:195–201
Barroso T et al (2009) J Supercrit Fluids 51:57–66
Wei X et al (2009) Talanta 79:739–745
Devalapally H et al (2007) Cancer Chemother Pharmacol 59:477–484
Gillies ER, Fréchet JMJ (2005) Bioconjug Chem 16:361–368
Angelos S et al (2009) J Am Chem Soc 131:12912–12914
Angelos S et al (2008) Angew Chem Int Ed 47:2222–2226
Dong L et al (2006) Nature 442:551–554
Reinicke S et al (2009) Soft Matter 5:2648–2657
Zhang K, Wu XY (2004) Biomaterials 25:5281–5291
Ishihara K, Negishi N, Shinohara I (1982) J Appl Polym Sci 27:1897–1902
Ishihara K et al (1983) J Appl Polym Sci 28:1321–1329
Saremi F, Tieke B (1998) Adv Mater 10:388–391
Seki T, Kojima J-Y, Ichimura K (1999) J Phys Chem B 103:10338–10340
Kumar SK, Hong J-D (2008) Langmuir 24:4190–4193
Wan P et al (2009) Adv Mater 21:4362–4365
Gomy C, Schmitzer AR (2007) Org Lett 9:3865–3868
Wu T et al (2009) Chem Mater 21:3788–3798
Saaem I, Tian J (2007) Adv Mater 19:4268–4271
Kang Y et al (2009) J Am Chem Soc 131:7538–7539
Hu Z et al (2008) Macromolecules 41:9508–9512
Alexeev VL et al (2003) Anal Chem 75:2316–2323
Alexeev VL et al (2004) Clin Chem 50:2353–2360
Lee Y-J, Pruzinsky SA, Braun PV (2004) Langmuir 20:3096–3106
Xu X, Goponenko AV, Asher SA (2008) J Am Chem Soc 130:3113–3119
Bang JH et al (2008) Langmuir 24:13168–13172
Kokufata E, Zhang Y-Q, Tanaka T (1991) Nature 351:302–304
Miyata T, Asami N, Uragami T (1999) Nature 399:766–769
Kim J, Nayak S, Lyon LA (2005) J Am Chem Soc 127:9588–9592
Chen Z et al (2008) J Mol Recognit 21:71–77
Qing G et al (2009) J Am Chem Soc 131:8370–8371
Tokarev I et al (2009) ACS Appl Mater Interfaces 1:532–536
Stouffer JM, McCarthy TJ (1988) Macromolecules 21:1204–1208
Erdelen C et al (1994) Langmuir 10:1246–1250
Serizawa T et al (2002) Macromolecules 35:2184–2189
Elam JH, Nygren H, Stenberg M (1984) J Biomed Mater Res 18:953–959
Huang H, Fulchiero EC, Penn LS (2005) Macromolecules 38:1028–1030
Beyer D et al (1998) Langmuir 14:3030–3035
Wang J et al (2003) J Biochem Biophys Methods 55:215–232
Gombotz WR et al (1991) J Biomed Mater Res 25:1547–1562
Ostaci R-V et al (2008) Langmuir 24:2732–2739
Kim J, Wacker BK, Elbert DL (2007) Biomacromolecules 8:3682–3686
Barner-Kowollik C et al (2008) Macromol Rapid Commun 29:1431–1437
Rühe J et al (2008) Macromolecules 41:873–878
Bouloussa O, Rondelez F, Semetey V (2008) Chem Commun 951–953
Maas JH et al (2003) Thin Solid Films 426:135–139
Barnes TJ et al (2008) Langmuir 24:7625–7627
Lutz J-F (2007) Angew Chem Int Ed 46:1018–1025
Bertrand P et al (2000) Macromol Rapid Commun 21:319–348
Menzel H, Griep-Raming N, Karger M (2004) Langmuir 20:11811–11814
Yang W, Bai H, Huang Z (2009) J Polym Sci Polym Chem 47:6852–6862
Lavanant L et al (2010) Macromol Biosci 10:101–108
Edmondson S, Armes SP (2009) Polym Int 58:307–316
Zhao B, Brittain WJ (2000) Macromolecules 33:342–348
Binder WH et al (2009) Macromolecules 42:7379–7387
Prucker O, Rühe J (1998) Langmuir 14:6893–6898
Matyjaszewski K et al (1999) Macromolecules 32:8716–8724
Pyun J, Kowalewski T, Matyjaszewski K (2003) Macromol Rapid Commun 24:1043–1059
Baum M, Brittain WJ (2002) Macromolecules 35:610–615
Husseman M et al (1999) Macromolecules 32:1424–1431
Brinks MK, Studer A (2009) Macromol Rapid Commun 30:1043–1057
de Boer B et al (2000) Macromolecules 33:349–356
Marques C, Joanny JF, Leibler L (1988) Macromolecules 21:1051–1059
Witmore MD, Noelandi J (1990) Macromolecules 23:3321–3339
Johner A, Joanny JF, Marques C (1991) Physica A 172:285–289
Tirrell M et al (1991) Polym J 23:641–649
Rubner MF (2003) pH-controlled fabrication of polyelectrolyte-multilayers: assembly and applications. In: Decher G, Schlenoff JB (eds) Multilayer thin-films. Wiley-VCH, Weinheim, p 133–154
Amiel C et al (1995) Macromolecules 28:3125–3134
Choi J, Rubner MF (2001) J Macromol Sci A 38:1191–1206
Chandekar A et al (2006) Langmuir 22:8071–8077
Murphy KA, Eisenhauer JM, Savin DA (2007) J Polym Sci B Polym Phys 46:244–252
Costa AC et al (2005) Eur Phys J E 18:159–166
Kiss É et al (2004) J Adhes 80:815–829
Hershkovits E, Tannenbaum A, Tannenbaum R (2008) Macromolecules 41:3190–3198
Yokoyama H et al (2005) Macromolecules 38:5180–5189
Oyane A et al (2005) Adv Mater 17:2329–2332
Andelman D, Joanny JF (2000) C R Acad Sci IV Phys:1153–1162
Balastre M et al (2002) Macromolecules 35:9480–9486
Styrkas DA et al (2000) Langmuir 16:5980–5986
Zhao X et al (2005) Langmuir 21:9597–9603
Laschewsky A et al (2001) Macromol Symp 164:323–340
Beebe DJ et al (2000) Proc Natl Acad Sci USA 97:13488–13493
Zhao B, Moore JS (2001) Langmuir 17:4758–4763
Edahiro J-I et al (2005) Biomacromolecules 6:970–974
Saunders BR, Liu R, Fraylich M (2009) Colloid Polym Sci 287:627–643
Serpe MJ et al (2005) Biomacromolecules 6:408–413
Li J et al (2007) Adv Funct Mater 17:3377–3382
Laschewsky A, Rekaï ED, Wischerhoff E (2001) Macromol Chem Phys 202:276–286
Mangeney C et al (2002) J Am Chem Soc 124:5811–5821
Jonas AM et al (2007) Macromolecules 40:4403–4405
Epstein N (1981) Fouling: technical aspects and fouling in heat exchangers. In: Somerscales E, Knudsen J (eds) Fouling of heat transfer equipment. Hemisphere, Washington, DC pp 31–53
Bryers JD (1994) Colloids Surf B 2:9–23
Schultz CL, Kunert KS, White R (2000) J Ind Microbiol Biotechnol 24:113–115
Wisniewski N, Richert M (2000) Colloids Surf B 18:197–219
Xu FJ, Neoh KG, Kang ET (2009) Prog Polym Sci 34:719–761
Ma H et al (2006) Adv Funct Mater 16:640–648
Tugulu S, Klok HA (2008) Biomacromolecules 9:906–912
Bozukova D et al (2008) Langmuir 24:6649–6658
Fukuda T et al (2007) J Polym Sci A Polym Chem 45:4795–4803
Nie F-Q et al (2004) Polymer 45:399–407
Cringus-Fundeanu I et al (2007) Langmuir 23:5120–5126
Petersen P et al (2009) Phys Status Solidi A 206:468–473
Bearinger JP et al (2003) Nat Mater 2:259–24
Patrucco E et al (2009) Biomacromolecules 10:3130–3140
Snellings GMBF et al (2000) Adv Mater 12:1959–1962
Gregorius K, Mouritsen S, Elsner HI (1995) J Immunol Methods 181:65–73
Chapman RG et al (2000) J Am Chem Soc 122:8303–8304
Lee Y-S et al (2003) Biosens Bioelectron 19:485–494
De Sousa Delgado A, Léonard M, Dellacherie E (2001) Langmuir 17:4386–4391
Martwiset S, Koh AE, Chen W (2006) Langmuir 22:8192–8196
Monchaux E, Vermette P (2007) Biomacromolecules 8:3668–3673
Perrino C et al (2008) Langmuir 24:8850–8856
Ekblad T et al (2008) Biomacromolecules 9:2775–2783
Kizhakkedathu JN et al (2009) Langmuir 25:3794–3801
Hucknall A, Rangarajan S, Chilkoti A (2009) Adv Mater 21:2441–2446
Trmcic-Cvitas J et al (2009) Biomacromolecules 10:2885–2894
Holmlin RE et al (2001) Langmuir 17:2841–2850
Ostuni E et al (2001) Langmuir 17:6336–6343
Kitano H et al (2010) Langmuir 26:6767–6774
Jiang S, Chen S (2008) Adv Mater 20:335–338
Chang Y et al (2008) Langmuir 24:5453–5458
Liu P-S et al (2009) Biomacromolecules 10:2809–2816
Reisch A et al (2008) J Mater Chem 18:4242–4245
Statz AR et al (2005) J Am Chem Soc 127:7972–7973
Ostuni E et al (2001) Langmuir 17:5605–5620
Unsworth LD, Sheardown H, Brash JL (2008) Langmuir 24:1924–1929
Klok H-A, Tugulu S (2008) Biomacromolecules 9:906–912
Yoshikawa C et al (2006) Macromolecules 39:2284–2290
Cunliffe D et al (2003) Langmuir 19:2888–2899
Kharlampieva E, Erel-Unal I, Sukhishvili S (2007) Langmuir 23:175–181
Burkert S et al (2010) Langmuir 26:1786–1795
Qin L et al (2009) Anal Chem 81:7206–7216
Zareie HM et al (2008) ACS Nano 2:757–765
Chan EWL, Park S, Yousaf MN (2008) Angew Chem Int Ed 47:6267–6271
Auernheimer J et al (2005) J Am Chem Soc 127:16107–16110
Liu D et al (2009) Angew Chem Int Ed 48: 4406–4408
Ernst O et al (2007) Lab Chip 7:1322–1329
Hentschel J et al (2008) Macromolecules 41:1073–1075
Zhu S et al (2009) Langmuir 25:10271–10278
Galaev IY et al (2006) Langmuir 23:35–40
Tan I et al (2009) ACS Appl Mater Interfaces 1:1869–1872
Yamanaka H et al (2003) Anal Chem 75:1658–1663
Ekins R, Chu F (1992) Ann Biol Clin 50:337–353
Zacher T, Wischerhoff E (2002) Langmuir 18:1748–1759
Löfås S, Johnsson B (1990) J Chem Soc Chem Commun 1526–1528
Piehler J et al (1996) Biosens Bioelectron 11:579–590
Arenkov P et al (2000) Anal Biochem 278:123–131
Huang N-P et al (2002) Langmuir 18:220–230
Klok H-A et al (2005) Biomacromolecules 6:1602–1607
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Wischerhoff, E., Badi, N., Laschewsky, A., Lutz, JF. (2010). Smart Polymer Surfaces: Concepts and Applications in Biosciences. In: Börner, H., Lutz, JF. (eds) Bioactive Surfaces. Advances in Polymer Science, vol 240. Springer, Berlin, Heidelberg. https://doi.org/10.1007/12_2010_88
Download citation
DOI: https://doi.org/10.1007/12_2010_88
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-20154-7
Online ISBN: 978-3-642-20155-4
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)