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Palladium-Catalyzed Aryl–Aryl Bond Formation Through Double C–H Activation

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C-H Activation

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 292))

Abstract

Aryl–aryl bond formation constitutes one of the most important subjects in organic synthesis. The recently developed direct arylation reactions for the formation of aryl–aryl bond have emerged as very attractive alternatives to traditional cross-coupling reactions. Particularly, the direct arylation through double C–H activation using the simple arenes as both coupling partners is a highly economic and attractive method. In this chapter, the recent progress of Pd-catalyzed aryl–aryl oxidative coupling reactions through double C–H activation is presented.

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Abbreviations

Ac:

Acetyl

acac:

Acetylacetonyl

atm:

Atmosphere

Bn:

Benzyl

BQ:

Benzoquinone

Bz:

Benzoyl

Piv:

Pivalyl

Tf:

Trifluoromethanesulfonyl

TFA:

Trifluoroacetic acid

TON:

Turnover number

Ts:

p-Toluenesulfonyl

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Acknowledgments

Financial support was provided by Chinese Academy of Sciences, National Natural Science Foundation of China (20872159, 20821002), and National Basic Research Program of China (973 Program 2009CB825300).

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Authors and Affiliations

  1. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai, 200032, China

    Shu-Li You & Ji-Bao Xia

Authors
  1. Shu-Li You
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  2. Ji-Bao Xia
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Correspondence to Shu-Li You .

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Editors and Affiliations

  1. Scripps Research Institute, N.Torrey Pines Rd. 10550, La Jolla, 92037, USA

    Jin-Quan Yu

  2. College of Chemistry, Peking University, Chengfu Road 202, Beijing, 100871, China, People's Republic

    Zhangjie Shi

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You, SL., Xia, JB. (2009). Palladium-Catalyzed Aryl–Aryl Bond Formation Through Double C–H Activation. In: Yu, JQ., Shi, Z. (eds) C-H Activation. Topics in Current Chemistry, vol 292. Springer, Berlin, Heidelberg. https://doi.org/10.1007/128_2009_18

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