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Solid Phase Organometallic Chemistry

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Combinatorial Chemistry on Solid Supports

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 278))

Abstract

This review covers recent results in the area of solid phase organometallic chemistry during the period 2000–2006. The focus is on carbon–carbon bond formation, but other aspects of organometallic reactions are also discussed. This includes the use of metal complexes as linkers, synthesis of biologically active compounds and complex natural product analogues, development of diversifying cleavage strategies, and testing the stability of new linkers and polymers under different reaction conditions. In many cases a direct comparison has been made between solid phase and solution phase chemistry. Thus, the advantages of performing reactions on polymer-supported substrates in terms of avoiding side reactions and facilitating product/metal separation are highlighted.

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Authors and Affiliations

  1. Organic Chemistry, Department of Chemical and Biological Engineering, Chalmers University of Technology, 41296, Göteborg, Sweden

    Natalie Ljungdahl, Karen Bromfield & Nina Kann

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  1. Natalie Ljungdahl
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  2. Karen Bromfield
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  3. Nina Kann
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Correspondence to Nina Kann .

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Stefan Bräse

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Ljungdahl, N., Bromfield, K., Kann, N. (2007). Solid Phase Organometallic Chemistry. In: Bräse, S. (eds) Combinatorial Chemistry on Solid Supports. Topics in Current Chemistry, vol 278. Springer, Berlin, Heidelberg. https://doi.org/10.1007/128_2007_125

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