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Fluorapatite-Gelatine-Nanocomposites: Self-Organized Morphogenesis, Real Structure and Relations to Natural Hard Materials

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Biomineralization I

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 270))

Abstract

The biomimetic system fluorapatite-gelatine (in aqueous solutions) is perfectly suited for the study of biomimetic steps closely related to steps in osteo- and dentinogenesis. Although representing a relatively low level of complexity, the biomimetic system still includes all aspects of complexity, such as metastability, self assembly, self-similarity, fractals, pattern-formation, hierarchy, and others. The present review is focused on the morphogenesis and real structure of fluorapatite-gelatine-nanocomposites and is structured in a sequence from macroscopic/bulk-properties to mesoscopic and finally microscopic observations, in part also supported by atomistic simulations. The field encompasses a large variety of components reaching from basic science to applications.

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References

  1. Bronner F, Farach-Carson M (eds) (2003) Bone Formation. Springer, Berlin Heidelberg New York

    Google Scholar 

  2. Jahnen-Dechent W (2004) In: Bäuerlein E (ed) Biomineralization, Progress in Biology, Molecular Biology and Application. 2nd Edn. Wiley, Weinheim

    Google Scholar 

  3. Teaford MF, Smith MM, Ferguson MWJ (eds) (2000) Development, Function and Evolution of Teeth. Cambridge University Press, Cambridge

    Book  Google Scholar 

  4. Reichenmiller K, Klein CH (2004) In: Bäuerlein E (ed) Biomineralization, Progress in Biology, Molecular Biology and Application, 2nd Edn. Wiley, Weinheim

    Google Scholar 

  5. Matthew AR, Jasiuk I, Taylor J, Rubin J, Ganey T, Apkarian RP (2003) Bone 33:270

    Article  Google Scholar 

  6. Gupta HS, Wagermaier W, Zickler GA, Aroush DRB, Funari SS, Roschger P, Wagner HD, Fratzl P (2005) Nano Lett 5:2108

    Article  CAS  Google Scholar 

  7. Tang R, Wang L, Orme CA, Bonstein T, Bush PJ, Nancollas GH (2004) Angew Chem Int Ed 43:2697

    Article  CAS  Google Scholar 

  8. Veis A (2004) Science 307:419

    Google Scholar 

  9. Heywood BR, Sparks NHC, Shellis RP, Weiner S, Mann S (1990) Connect Tiss Res 25:103

    Article  CAS  Google Scholar 

  10. Landis WJ, Hodgens KJ, Arena J, Song MJ, McEwen BF (1996) Micros Res Technol 33:192

    Article  CAS  Google Scholar 

  11. Kim HW, Kim HE, Salih V (2005) Biomaterials 26:5221

    Article  CAS  Google Scholar 

  12. Kim HW, Yoon BH, Kim HE (2005) J Mater Sci: Mater in Med 16:1105

    Article  CAS  Google Scholar 

  13. Chang MC, Ko CC, Douglas WH (2005) J Mater Sci 40:2723

    Article  CAS  Google Scholar 

  14. Furuichi K, Oaki Y, Imai H (2006) Chem Mater 18:229

    Article  CAS  Google Scholar 

  15. Kniep R, Busch S (1996) Angew Chem 108:2787

    Article  Google Scholar 

  16. Kniep R, Busch S (1996) Angew Chem Int Ed Engl 35:2624

    Article  CAS  Google Scholar 

  17. Busch S, Dolhaine H, DuChesne A, Heinz S, Hochrein O, Laeri F, Podebrad O, Vietze U, Weiland T, Kniep R (1999) Eur J Inorg Chem 10:1643

    Article  Google Scholar 

  18. Busch S, Schwarz U, Kniep R (2001) Chem Mater 13:3260

    Article  CAS  Google Scholar 

  19. Busch S, Schwarz U, Kniep R (2003) Adv Func Mater 13:189

    Article  CAS  Google Scholar 

  20. Simon P, Carrillo-Cabrera W, Formanek P, Gobel C, Geiger D, Ramlau R, Tlatlik H, Buder J, Kniep R (2004) J Mater Chem 14:2218

    Article  CAS  Google Scholar 

  21. Göbel C, Simon P, Buder J, Tlatlik H, Kniep R (2004) J Mater Chem 14:2225

    Article  CAS  Google Scholar 

  22. Kniep R (2004) In: Müller A, Quadbeck-Seeger HJ, Diemann E (eds) Facetten einer Wissenschaft. Wiley, Weinheim

    Google Scholar 

  23. Simon P, Schwarz U, Kniep R (2005) J Mater Chem 15:4992

    Article  CAS  Google Scholar 

  24. Tlatlik H, Simon P, Kawska A, Zahn D, Kniep R (2006) Angew Chem Int Ed 45:1905

    Article  CAS  Google Scholar 

  25. Simon P, Zahn D, Lichte H, Kniep R (2006) Angew Chem Int Ed 45:1911

    Article  CAS  Google Scholar 

  26. Arends J, Davidson CL (1975) Calcif Tissue Res 18:65

    Article  CAS  Google Scholar 

  27. Verbeek RMH, De Maeyer CAP, Droessens FCM (1995) Inorg Chem 34:2084

    Article  Google Scholar 

  28. Nancollas GH, Wu WJ (2000) J Cryst Growth 211:137

    Article  CAS  Google Scholar 

  29. Zhang HG, Zhu Q, Wang Y (2005) Chem Mater 17:5824

    Article  CAS  Google Scholar 

  30. Wilke K-Th, Bohm J (1988) Kristallzüchtung. Verlag Harri Deutsch, Thun, Frankfurt/Main, Germany

    Google Scholar 

  31. Henisch HK (1996) Crystal Growth in Gels. Dover Publications, Inc., New York

    Google Scholar 

  32. Busch S (1998) PhD Thesis, University of Technology, Darmstadt, Germany

    Google Scholar 

  33. Ostwald's Klassiker der exakten Naturwissenschaften: Selbstorganisation chemischer Strukturen (1987) Akademische Verlagsgesellschaft Geest & Portig KG, Leipzig

    Google Scholar 

  34. Grigor'ev DP (1965) Ontongeny of Minerals. Israel Program for Scientific Translations, Jerusalem

    Google Scholar 

  35. Prymak O, Sokolova V, Peitsch T, Epple M (2006) Cryst Growth & Design 6:499

    Google Scholar 

  36. Haeckel E (1925) Kristallseelen. Verlag Alfred Kröner, Leipzig (Reprint) (2005) Hesse & Becker, Leipzig

    Google Scholar 

  37. Mandelbrot BB (1991) Die fraktale Geometrie der Natur. Birkhäuser Verlag, Basel

    Google Scholar 

  38. Maleev MN (1972) Tschermaks Min Petr Mitt 18:1216

    Article  Google Scholar 

  39. POVRAY 3.1e@, 1991–1999, The Persistence of Vision Team, http://www.povray.org

  40. Schröder HE (1992) Orale Strukturbiologie. Thieme, Stuttgart

    Google Scholar 

  41. Sheldrick GM (1997) SHELXL 97-2. Program for refinement of crystal structures. University of Göttingen, Göttingen

    Google Scholar 

  42. Akselrud L, Grin J, Pecharsky V, Zavalij P. Computer program package WINCSD. Lviv National University, Ukraine; Max-Plank Institute, Germany; Ames Lab, USA; Binghamton University, USA

    Google Scholar 

  43. Sudarsanan K, Mackie PE, Young RRA (1972) Mat Res Bull 7:1331

    Article  CAS  Google Scholar 

  44. Mackie PE, Young RA (1973) J Appl Chryst 6:26

    Article  CAS  Google Scholar 

  45. Posner AS, Diorio AF (1967) Acta Cryst 1:1948

    Google Scholar 

  46. Sudarsanan K, Young RA (1969) Acta Crystallogr B 25:1534

    Article  CAS  Google Scholar 

  47. Newesely H, Helmke JG (1971) Biomineralization 3:39

    Google Scholar 

  48. LeGeros RZ, Bonel G, Legeros R (1978) Calcif Tiss Res 26:111

    Article  CAS  Google Scholar 

  49. Berman A, Addadi L, Weiner S (1988) Nature 331:546

    Article  CAS  Google Scholar 

  50. Young RA, van der Lugt W, Elliott JC (1969) Nature 223:729

    Article  CAS  Google Scholar 

  51. Newesely H, Müller H (1988) Z Kristallogr 182:197

    Google Scholar 

  52. Young RA, Holcomb DW (1984) Calcif Tissue Int 36:60

    Article  CAS  Google Scholar 

  53. Freud F, Knobel MJCS (1976) Dalton 6/2151:1136

    Google Scholar 

  54. Berman A, Addadi L, Weiner S (1988) Nature 331:546

    Article  CAS  Google Scholar 

  55. Mann S (2001) In: Compton RG, Davies SG, Evans J (eds) Biomineralization. Oxford University Press, Oxford

    Google Scholar 

  56. Schwenzer N (1985) Zahn- Mund- Kiefer- Heilkunde, Vol 1–4. Thieme, Stuttgart

    Google Scholar 

  57. Cölfen H, Antonietti M (2005) Angew Chem 117:5714

    Article  Google Scholar 

  58. Cölfen H, Antonietti M (2005) Angew Chem Int Ed 44:5576

    Article  CAS  Google Scholar 

  59. Thompson JB, Kindt JH, Drake B, Hansma HG, Morse DE, Hansma PK (2001) Nature 414:773

    Article  CAS  Google Scholar 

  60. Currey J (2001) Nature 414:699

    Article  CAS  Google Scholar 

  61. Fantner GE, Hassenkam T, Kindt JH, Weaver JC, Birkedal H, Pechenik L, Cutroni JA, Cidade GA G, Stucky GD, Morse DE, Hansma PK (2005) Nature Mater 4:612

    Article  CAS  Google Scholar 

  62. Zahn D, Hochrein O (2003) Phys Chem Chem Phys 5:4004

    Article  CAS  Google Scholar 

  63. MacKerell AD, Bashford D, Bellott RL, Dunbrack RL, Evanseck JD, Field MJ, Fischer S, Gao J, Guo H, Ha S, Joseph-McCarthy D, Kuchnir L, Kuczera K, Lau FT K, Mattos C, Michnick S, Ngo T, Nguyen DT, Prodhom B, Reiher WE, Roux B, Schlenkrich M, Smith J, Stote CR, Straub J, Watanabe M, Wiorkiewicz-Kuczera J, Yin D, Karplus DM (1998) J Phys Chem B 102:3586

    Article  CAS  Google Scholar 

  64. Kawska A, Brickmann J, Hochrein O, Zahn D (2005) Z Anorg Allg Chem 631:1172

    Article  CAS  Google Scholar 

  65. Kawska A, Brickmann J, Kniep R, Hochrein O, Zahn D (2006) J Chem Phys 124:24513

    Article  CAS  Google Scholar 

  66. Yamashita K, Oikawa N, Umegaki T (1996) Chem Mater 8:2697

    Article  CAS  Google Scholar 

  67. Calvert P, Mann S (1997) Nature 386:127

    Article  CAS  Google Scholar 

  68. Lang SB (1966) Nature 212:704

    Article  Google Scholar 

  69. Kitagawa K, Morita T, Kimura S (2005) Angew Chem Int Ed 117:6488

    Article  Google Scholar 

  70. Lichte H, Lehmann M (2002) In: Advances in Imaging and Electron Physics, Electron Holography: A Powerful Tool for Analysis of Nanostructures. Elsevier, New York 123:225

    CAS  Google Scholar 

  71. Lichte H, Reibold M, Brand K, Lehmann M (2002) Ultramicroscopy 93:199

    Article  CAS  Google Scholar 

  72. Höhling HJ (1966) Die Bauelemente von Zahnschmelz und Dentin aus Morphologischer, Chemischer und Struktureller Hinsicht. Hanser, Munich

    Google Scholar 

  73. Goldberg M, Carreau JP, Arends J (1987) J Arch Oral Biol 32:765

    Article  CAS  Google Scholar 

  74. Edgar WM, Mullane DM (1990) Saliva and Dental Health. British Dental Journal, London

    Google Scholar 

  75. Okazaki M, Tokahashi J, Kimura H (1989) J Osaka Univ Dent Sch 29:47

    CAS  Google Scholar 

  76. Daculsi G, Menanteau J, Kerebel LM (1984) Calcif Tissue Int 36:550

    Article  CAS  Google Scholar 

  77. Schatz A, Martin JJ (1965) Zahnheilkunde 26:191

    Google Scholar 

  78. Schwenzer N (1988) Zahn- Mund- Kiefer- Heilkunde, Vol 4: Konservierende Zahnheilkunde. Thieme, Stuttgart

    Google Scholar 

  79. Braunbarth C, Franke K, Poth T, Schechner G, Kniep R, Kropf C, Wülknitz P (2003) VDI-Reports No. 1803

    Google Scholar 

  80. Zahn D, Hochrein O (2003) Phys Chem Chem Phys 5:4004

    Article  CAS  Google Scholar 

  81. Zahn D (2004) Z Anorg Allg Chem 630:1507

    Article  CAS  Google Scholar 

  82. Hochrein O, Zahn D, Kniep R, Brickmann J (2004) Z Anorg Allg Chem 630:1740

    Article  Google Scholar 

  83. Zahn D, Hochrein O (2005) Z Anorg Allg Chem 631:1134

    Article  CAS  Google Scholar 

  84. Hochrein O, Kniep R, Zahn D (2005) Chem Mater 17:1978

    Article  CAS  Google Scholar 

  85. Zahn D, Hochrein O (2006) Z Anorg Allg Chem 632:79

    Article  CAS  Google Scholar 

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Acknowledgments

We would like to thank the Fonds der Chemischen Industrie for generous support. Parts of this work were funded by the Deutsche Forschungsgemeinschaft (SPP 1117 “Prinzipien der Biomineralisation”).

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Correspondence to Rüdiger Kniep .

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Kensuke Naka

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Kniep, R., Simon, P. (2006). Fluorapatite-Gelatine-Nanocomposites: Self-Organized Morphogenesis, Real Structure and Relations to Natural Hard Materials. In: Naka, K. (eds) Biomineralization I. Topics in Current Chemistry, vol 270. Springer, Berlin, Heidelberg . https://doi.org/10.1007/128_053

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