Anatomically Constrained Deformation for Design of Cranial Implant: Methodology and Validation

  • Ting Wu
  • Martin Engelhardt
  • Lorenz Fieten
  • Aleksandra Popovic
  • Klaus Radermacher
Part of the Lecture Notes in Computer Science book series (LNCS, volume 4190)


We present a new approach for cranial implant design which uses anatomical constrained deformation based on reference models. The methodological framework contains three steps: patient-specific generation of the reference model containing the anatomical constraints about the skull shape; determination of the spatial correspondence between the patient skull and the reference model by 3D matching; adaptive deformation of the fragment on the reference model corresponding to the defect area on the patient skull for implant design. The proposed method was validated by simulating the reconstruction of artificially generated defects on healthy skulls. The validation results show that this approach can generate implant geometry very fast and with satisfactory quality. This approach also outperforms the surface interpolation method in reconstructing cranial defects.


Reference Model Reconstruction Error Defect Area Reconstruction Quality Spatial Correspondence 
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  1. 1.
    Sanan, A., Haines, S.J.: Repairing holes in the head: a history of cranioplasty. Neurosurgery 40, 588–603 (1997)CrossRefGoogle Scholar
  2. 2.
    Dujovny, M., Aviles, A., Agner, C., Fernandez, P., Charbel, F.T.: Cranioplasty: cosmetic or therapeutic? Surg. Neurol. 47, 238–241 (1997)CrossRefGoogle Scholar
  3. 3.
    Eufinger, H., Wehmöller, M., Machtens, E., Heuser, L., Harders, A., Kruse, D.: Reconstruction of craniofacial bone defects with individual alloplastic implants based on CAD/CAM-manipulated CT-data. J. Cranio Maxillofac Surg. 23, 175–181 (1995)CrossRefGoogle Scholar
  4. 4.
    Heissler, E., Fischer, F.S., Bolouri, S., Lehmann, T., Mathar, W., Gebhardt, A., et al.: Custom-made cast titanium implants produced with CAD/CAM for the reconstruction of cranium defects. Int. J. Oral Maxillofac Surg. 27, 334–338 (1998)CrossRefGoogle Scholar
  5. 5.
    Lee, M.Y., Chang, C.C., Lin, C.C., Lo, L.J., Chen, Y.: Custom implant design for patients with cranial defects. IEEE Eng. Med. Biol. Mag. 21(2), 38–44 (2002)CrossRefGoogle Scholar
  6. 6.
    Müller, A., Krishnan, K.G., Uhl, E., Mast, G.: The application of rapid prototyping techniques in cranial reconstruction and preoperative planning in neurosurgery. J. Craniofac Surg. 14, 899–914 (2003)CrossRefGoogle Scholar
  7. 7.
    Sauret, V., Linney, A.D., Richards, R.: Computer assisted surgery: the use of digital images in enabling computerized design and manufacture of titanium implants. Imaging 14, 464–471 (2002)Google Scholar
  8. 8.
    Carr, J.C., Fright, W.R., Beatson, R.K.: Surface interpolation with radial basis functions for medical imaging. IEEE Transactions in Medical Imaging 16(1), 96–107 (1997)CrossRefGoogle Scholar
  9. 9.
    Min, K.J., Dean, D.: Highly Accurate CAD Tools for Cranial Implants. In: Ellis, R.E., Peters, T.M. (eds.) MICCAI 2003. LNCS, vol. 2878, pp. 99–107. Springer, Heidelberg (2003)CrossRefGoogle Scholar
  10. 10.
    Kolar, J.C., Salter, E.M.: Craniofacial anthropometry practical measurements of the head and face for clinical, surgical and research use. Charles Thomas Publisher Ltd., USA (1996)Google Scholar
  11. 11.
    Horn, B.K.P.: Closed-form solution of absolute orientation using unit quaternions. J. Opt. Soc. Am. A 4(4), 629–642 (1987)CrossRefMathSciNetGoogle Scholar
  12. 12.
    Besl, P.J., McKay, N.D.: A method for registration of 3-d shapes. IEEE Transactions on Pattern Analysis and Machine Intelligence 14(2), 239–256 (1992)CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • Ting Wu
    • 1
  • Martin Engelhardt
    • 2
  • Lorenz Fieten
    • 1
  • Aleksandra Popovic
    • 1
  • Klaus Radermacher
    • 1
  1. 1.Helmholtz Institute for Biomedical EngineeringRWTH Aachen UniversityAachenGermany
  2. 2.Clinic for NeurosurgeryRuhr-UniversityBochumGermany

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