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Reasoning Web International Summer School

Reasoning Web 2006: Reasoning Web pp 184–196Cite as

Integrating Web Resources to Model Protein Structure and Function

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Part of the book series: Lecture Notes in Computer Science ((LNISA,volume 4126))

Abstract

In this paper we address computational aspects of protein structure and function, including prediction of secondary structure, folding, structure determination from Nuclear Magnetic Resonance data, modelling of protein interactions, and metabolic pathways. The subject is introduced with an overview of protein structure and chemistry and the algorithms and representations used to model protein structures. The main focus of the paper is the integration of information from sources relevant to protein structure modelling, such as structure databases and modelling servers, a task made difficult by the heterogeneity of formats, the diversity of data sources, and the sheer volume of information available, making evident the need for a standard framework for data sharing, i.e. the Semantic Web. To help solve this problem, we present tools being developed according to the concept of a Semantic Web. These include the UniProtRDF project and tools currently implemented on the Chemera molecular modelling software which can facilitate the search and application of information available from Internet servers and databases.

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Author information

Authors and Affiliations

  1. Dep. de Informática, Universidade Nova de Lisboa, 2825, Monte de Caparica, Portugal

    Ludwig Krippahl

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  1. Ludwig Krippahl
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Editor information

Editors and Affiliations

  1. Centro de Inteligência Artificial, Departamento de Informática, Universidade Nova de Lisboa, 2829-516, Caparica, Portugal

    Pedro Barahona

  2. Institute for Informatics, University of Munich, Oettingenstr. 67, D-80538, München, Germany

    François Bry

  3. Faculty of Computer Science, Free University of Bozen-Bolzano, Piazza Domenicani 3, I-39100, Bozen-Bolzano BZ, Italy

    Enrico Franconi

  4. IVS - Semantic Web Group, Leibniz University of Hannover, Appelstr. 4, D-30167, Hannover, Germany

    Nicola Henze

  5. University of Manchester, UK

    Ulrike Sattler

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© 2006 Springer-Verlag Berlin Heidelberg

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Krippahl, L. (2006). Integrating Web Resources to Model Protein Structure and Function. In: Barahona, P., Bry, F., Franconi, E., Henze, N., Sattler, U. (eds) Reasoning Web. Reasoning Web 2006. Lecture Notes in Computer Science, vol 4126. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11837787_8

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  • DOI: https://doi.org/10.1007/11837787_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-38409-0

  • Online ISBN: 978-3-540-38412-0

  • eBook Packages: Computer ScienceComputer Science (R0)

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