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Estimating Diameters of Pulmonary Nodules with Competition-Diffusion and Robust Ellipsoid Fit

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Computer Vision for Biomedical Image Applications (CVBIA 2005)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 3765))

Abstract

We propose a new technique to extract a pulmonary nodule from helical thoracic CT scans and estimate its diameter. The technique is based on a novel segmentation, or label-assignment, framework called competition-diffusion (CD), combined with robust ellipsoid fitting (EF). The competition force defined by replicator equations draws one dominant label at each voxel, and the diffusion force encourages spatial coherence in the segmentation map. CD is used to reliably extract foreground structures, and nodule like objects are further separated from attached structures using EF. Using ground-truth measured manually over 1300 nodules taken from more than 240 CT volumes, the performance of the proposed approach is evaluated in comparison with two other techniques: Local Density Maximum algorithm and the original EF. The results show that our approach provides the most accurate size estimates.

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References

  1. van Ginneken, B., ter Harr Romeny, B.M., Viergever, M.A.: Computer-aided diagnosis in chest radiography: A survey. IEEE TMI 20, 1228–1241 (2001)

    Google Scholar 

  2. Reeves, A.P., Kostis, W.J.: Computer-aided diagnosis of small pulmonary nodules. Seminars in Ultrasound, CT, and MRI 21, 116–128 (2000)

    Article  Google Scholar 

  3. Ko, J.P., Naidich, D.P.: Computer-aided diagnosis and the evaluation of lung disease. J. Thorac Imaging 19, 136–155 (2004)

    Article  Google Scholar 

  4. Armato, S., et al.: Computerized detection of pulmonary nodules on CT scans. RadioGraphics 19, 1303–1311 (1999)

    Google Scholar 

  5. Fan, L., Novak, C., Qian, J., Kohl, G., Naidich, D.: Automatic detection of lung nodules from multi-slice low-dose CT images. In: SPIE Med. Imag. (2001)

    Google Scholar 

  6. Lee, Y., et al.: Automated detection of pulmonary nodules in helical CT images based on an improved template-matching technique. IEEE TMI 20, 595–604 (2001)

    Google Scholar 

  7. Henschke, C.I., et al.: CT screening for lung cancer: Frequency and significance of part-solid and nonsolid nodules. Am. J. Roentgen. 178, 1053–1057 (2002)

    Google Scholar 

  8. Okada, K., Comaniciu, D., Krishnan, A.: Robust anisotropic Gaussian fitting for volumetric characterization of pulmonary nodules in multislice CT. IEEE TMI 24, 409–423 (2005)

    Google Scholar 

  9. Kubota, T., Espinal, F.: Reaction-diffusion systems for hypothesis propagation. In: ICPR 2000, vol. III, pp. 547–550 (2000)

    Google Scholar 

  10. Pelillo, M.: The dynamics of nonlinear relaxation labeling processes. Journal of Mathematical Imaging and Vision 7, 309–323 (1997)

    Article  MathSciNet  Google Scholar 

  11. Carpenter, G.A., Grossberg, S.: A massively parallel architecture for a self-organizing neural pattern recognition machine. Computer Vision, Graphics, and Image Processing 37, 54–115 (1987)

    Article  Google Scholar 

  12. Tek, H., Kimia, B.: Volumetric segmentation of medical images by three-dimensional bubbles. CVIU 64, 246–258 (1997)

    Google Scholar 

  13. Zhu, S., Mumford, D.: Prior learning and gibbs reaction-diffusion. PAMI 19, 1236–1250 (1997)

    Google Scholar 

  14. Zhao, B., Gamsu, G., Ginsberg, M.S., Jiang, L., Schwartz, L.H.: Automatic detection of small lung nodules on CT utilizing a local density maximum algorithm. Journal of Applied Clinical Medical Physics 4, 248–260 (2003)

    Article  Google Scholar 

  15. Kubota, T., Okada, K.: Competition-diffusion and its properties. Technical report, Siemens Medical Solutions USA, CAD Solutions (2005)

    Google Scholar 

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© 2005 Springer-Verlag Berlin Heidelberg

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Kubota, T., Okada, K. (2005). Estimating Diameters of Pulmonary Nodules with Competition-Diffusion and Robust Ellipsoid Fit. In: Liu, Y., Jiang, T., Zhang, C. (eds) Computer Vision for Biomedical Image Applications. CVBIA 2005. Lecture Notes in Computer Science, vol 3765. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11569541_33

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  • DOI: https://doi.org/10.1007/11569541_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-29411-5

  • Online ISBN: 978-3-540-32125-5

  • eBook Packages: Computer ScienceComputer Science (R0)

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