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Yellow Biotechnology I pp 79–110Cite as

Drosophila and the Hallmarks of Cancer

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Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 135))

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Abbreviations

Hh:

Hedgehog

Dpp:

Decapentaplegic

Wg:

Wingless

JAK/STAT:

Janus kinase/signal transducer and activator of transcription

lgl:

Lethal giant larvae

scrib:

Scribbled

dlg:

Discs large

EGF:

Epidermal growth factor

MAPK:

Mitogen-activated protein kinase

JNK:

c-Jun N-terminal kinase

TNF:

Transforming growth factor

UAS:

Upstream activating sequence

G-TRACE:

Gal4 technique for realtime and clonal expression

FRT:

Flippase recognition target

MARCM:

Mosaic analysis with a repressible cell marker

esg:

Escargot

csp:

Caspase

Pdm1:

POU domain protein 1

CSC:

Cancer stem cells

Dronc:

Drosophila Nedd2-like caspase

Dcp-1:

Death caspase-1

PDGF:

Platelet-derived growth factor

psr:

Phosphatidylserine receptor

dSPARC:

Drosophila homologue of secreted protein, acidic, cysteine-rich

ISC:

Intestinal stem cells

MEN:

Multiple endocrine neoplasia

RET:

Rearranged during transfection

Csk:

C-terminal Src kinase

PcG:

Polycomb group

RB:

Retinoblastoma

TP53:

Tumor protein 53

DIAP1:

Drosophila melanogaster inhibitor of apoptosis-1

IAP:

Inhibitor of apoptosis

BCL:

B-cell lymphoma

Debcl:

Death executioner Bcl-2

BMP:

Bone morphogenetic protein

piwi:

P-element induced wimpy testis

GSC:

Germline stem cell

FGF:

Fibroblast growth factor

LINE:

Long interspersed (transposable) elements

RNAi:

Ribonucleic acid interference

VEGF:

Vascular endothelial growth factor

TSP-1:

Thrombospodin-1

btl:

Breathless

HIF:

Hypoxia-inducible factor

dVHL:

Drosophila Von Hippel–Lindau tumor suppressor

B. mori :

Bombyx mori

FGFR:

Fibroblast growth factor receptor

EGFR:

Epidermal growth factor receptor

vFGF:

Viral fibroblast growth factor

IMD:

Immune deficiency pathway

EMT:

Epithelial–mesenchymal transition

MMP:

Matrix metalloproteinase

A-P boundary:

Anterior–posterior boundary

Src:

Sarcoma

Rho1:

Rho GTPase

byn:

Brachyenteron

GFP:

Green fluorescent protein

SYCP1:

Synaptonemal complex protein 1

l(3)mbt:

Lethal 3 malignant brain tumor

ATP:

Adenosine triphosphate

GLUT1:

Glucose transporter 1

TOR:

Target of rapamycin

Inr/PI3K:

Insulin receptor/phosphoinositide 3-kinase

TrxG:

Trithorax group

P. aeruginosa :

Pseudomonas aeruginosa

IL:

Interleukin

NF-kB:

Nuclear factor kappa-light-chain-enhancer of activated B-cells

Ubc9:

Ubiquitin carrier protein 9

APC:

Adenomatous polyposis coli

TSC:

Tuberous sclerosis complex

S6K:

Ribosomal protein S6 kinase

ROS:

Reactive oxygen species

NF:

Neurofibromatosis

RTK:

Receptor tyrosine kinase

Shh:

Sonic hedgehog

Ihh:

Indian hedgehog

Dhh:

Desert Hedgehog

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  1. Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus

    Theodoulakis Christofi & Yiorgos Apidianakis

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    Andreas Vilcinskas

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Christofi, T., Apidianakis, Y. (2013). Drosophila and the Hallmarks of Cancer. In: Vilcinskas, A. (eds) Yellow Biotechnology I. Advances in Biochemical Engineering/Biotechnology, vol 135. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10_2013_190

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