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Mesenchymal Stem Cells as Cellular Immunotherapeutics in Allogeneic Hematopoietic Stem Cell Transplantation

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Mesenchymal Stem Cells - Basics and Clinical Application II

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Abbreviations

APC:

Antigen presenting cells

BM:

Bone marrow

CR:

Complete response

DC:

Dendritic cell

EBMT:

European Group for Blood and Marrow Transplantation

GvHD:

Graft-versus-host disease

GvL:

Graft-versus-leukemia

(allo-)HSCT:

(allogeneic) Hematopoietic stem cell transplantation

HLA(-G):

Human leukocyte antigen(-G)

HSC:

Hematopoietic stem cell

IDO:

Indoleamine-2,3,-dioxygenase

ISCT:

International Society for Cellular Therapy

IFN:

Interferon

IL:

Interleukin

MSC:

Mesenchymal stem cell

OR:

Overall response

PR:

Partial response

PBSC:

Peripheral blood stem cell

PD-L:

Ligand of the programmed death receptor

PGE2 :

Prostaglandin E2

PL:

Platelet lysate

TGF:

Transforming growth factor

Th:

T helper cells

TNF:

Tumor necrosis factor

UCB:

Umbilical cord blood

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Papewalis, C., Topolar, D., Götz, B., Schönberger, S., Dilloo, D. (2013). Mesenchymal Stem Cells as Cellular Immunotherapeutics in Allogeneic Hematopoietic Stem Cell Transplantation. In: Weyand, B., Dominici, M., Hass, R., Jacobs, R., Kasper, C. (eds) Mesenchymal Stem Cells - Basics and Clinical Application II. Advances in Biochemical Engineering/Biotechnology, vol 130. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10_2012_158

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