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Artificial Receptors

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Biosensing for the 21st Century

Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 109))

Abstract

Herein I will provide a brief overview of artificial receptors with emphasis on molecularly imprinted polymers (MIPs) and their applications. Alternative techniques to produce artificial receptors such as in silico designed and modelled polymers as well as different receptors designed using libraries of more or less natural composition will also be mentioned. Examples of these include aptamers and bio-nanocomposites. The physical presentation of the receptors is important and may depend on the application. Block polymerization of MIPs and grinding to particles of suitable size used to be the preferred technique, but today beaded materials can be produced in sizes down to nanobeads and also nanofibers can be used to increase available surface area and thereby capacity. For sensor applications it may be attractive to include the artificial receptors in surface coatings or in membrane structures. Different composite designs can be used to provide additional desirable properties. MIPs and other artificial receptors are gaining rapidly increasing attention in very shifting application areas and an attempt to provide a systematic account for current applications has been made with examples from separation, solid-phase extraction, analysis, carbohydrate specific experiments, and MIPs-directed synthesis.

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Authors and Affiliations

  1. Lund University Box 124, S-22100, Lund, Sweden

    Bengt Danielsson

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  1. Bengt Danielsson
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Correspondence to Bengt Danielsson .

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Reinhard Renneberg Fred Lisdat

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© 2007 Springer-Verlag Berlin Heidelberg

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Danielsson, B. (2007). Artificial Receptors. In: Renneberg, R., Lisdat, F. (eds) Biosensing for the 21st Century. Advances in Biochemical Engineering/Biotechnology, vol 109. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10_2007_088

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