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Bulking Agents

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Female Pelvic Medicine and Reconstructive Pelvic Surgery

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Abstract

Murless, in 1938, first reported on injection of sodium morrhuate around the urethra [1], and since then various materials have been injected for urinary incontinence as an alternative to surgery. Quackels [2] reported paraffin wax in 1955 and Sachse [3] used sclerosing agents in 1963. The initial results were poor and significant complications such as pulmonary emboli and urethral sloughing were seen. Polytetrafluoroethylene (Teflon) paste was first introduced by Berg [4] and then popularized by Politano [5] in the 1970s. Shortliffe et al. [6] published the first report on glutaraldehyde cross-linked collagen and more recently autologous fat injection [7] has been described. N ewer agents, such as silicone microparticles [8] and injectable microballoons, have also been reported [9].

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Author information

Authors and Affiliations

  1. Division of Urology, University of Toronto, Sunnybrook and Women’s Health Science Centre, Toronto, Ontario, Canada

    Professor Sender Herschorn

  2. Department of Obstetrics and Gynecology, University of Toronto, Sunnybrook and Women’s Health Sciences Centre, Toronto, Ontario, Canada

    Dr Patricia Lee

Authors
  1. Professor Sender Herschorn
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  2. Dr Patricia Lee
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Editor information

Editors and Affiliations

  1. Urogynecology Unit, Mount Sinai Hospital, Toronto, Ontario, Canada

    H. P. Drutz BA, MD, FRC(C), FACOG, FSOGC

  2. Division of Urology, University of Toronto, Toronto, Ontario, Canada

    S. Herschorn BSc, MDCM, FRCSC

  3. Division of Gastroenterology, Department of Medicine, University of Toronto, Toronto Hospital, Toronto, Ontario, Canada

    N. E. Diamant MD, FRCP(C)

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© 2003 Springer-Verlag London Limited

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Herschorn, S., Lee, P. (2003). Bulking Agents. In: Drutz, H.P., Herschorn, S., Diamant, N.E. (eds) Female Pelvic Medicine and Reconstructive Pelvic Surgery. Springer, London. https://doi.org/10.1007/1-84628-238-1_36

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  • DOI: https://doi.org/10.1007/1-84628-238-1_36

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-237-9

  • Online ISBN: 978-1-84628-238-6

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