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Female Pelvic Medicine and Reconstructive Pelvic Surgery pp 213–221Cite as

Vulvodynia and Vestibulitis

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Abstract

Chronic vulvar pain was first described in the late 1800s as hyperesthesia by Skene [1] with further reports by Thomas and Munde [2] and Kelly in the 1920s [3]. In the 1970s, the terms burning vulvar syndrome, psychosomatic vulvovaginitis and vestibular adenitis became popular.

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References

  1. Skene AJC. Treatise on the Disease of Women. New York: Appleton, 1889.

    Google Scholar 

  2. Thomas TG, Munde PF. A Practical Treatise on the Disease of Women. Philadelphia: Lea Brothers, 1891.

    Google Scholar 

  3. Kelly HA. Gynecology. New York: Appleton, 1928.

    Google Scholar 

  4. Report of the ISSVD. Burning vulva syndrome. J Reprod Med 1984;29:457.

    Google Scholar 

  5. Friedrich EG Jr. Vulvar vestibulitis syndrome. J Reprod Med 1987;32:110–14.

    PubMed  Google Scholar 

  6. Woodruff JD, Parmley TH. Infection of the minor vestibular glands. Obstet Gynecol 1983;62:609–10.

    PubMed  CAS  Google Scholar 

  7. McKay M. Vulvodynia: a multifactorial clinical problem. Arch Dermatol 1989;125:256–62.

    Article  PubMed  CAS  Google Scholar 

  8. Denbow ML, Byrne MA. Prevalence, causes and outcome of vulvar pain in a genitourinary medicine clinic population. Int J STD AIDS 1998;9(2):88–91.

    Article  PubMed  CAS  Google Scholar 

  9. Goetsch MF. Vulvar vestibulitis: Prevalence and historic features in a general gynecologic practice population. Am J Obstet Gynecol 1991;164:1609–16.

    PubMed  CAS  Google Scholar 

  10. Baggish SM, Miklos JR. Vulvar pain syndrome: A review. Obstet Gynecol Surv 1995;50:618–27.

    Article  PubMed  CAS  Google Scholar 

  11. Ashman RB, Ott AK. Autoimmunity as a factor in recurrent vaginal candidosis and the minor vestibular gland syndrome. J Reprod Med 1989;4:264–6.

    Google Scholar 

  12. Turner MLC, Marinoff SC. Association of human papillomavirus with vulvodynia and the vulvar vestibulitis syndrome. J Reprod Med 1988;33:533–7.

    PubMed  CAS  Google Scholar 

  13. Wilkinson EJ, Guerrero E, Daniel R, Shah K, Stone IK, Hardt NS, Friedrich EG, Jr. Vulvar vestibulitis is rarely associated with human papillomavirus infection types 6, 11, 16 or 18. Int J Gynecol Pathol 1993;12(4):344–9.

    PubMed  CAS  Google Scholar 

  14. Bergeron C, Moyal-Barracco M, Pelisse M, Lewin P. Vulvar vestibulitis. Lack of evidence for a human papillomavirus etiology. J Reprod Med 1994;39(12):936–8.

    PubMed  CAS  Google Scholar 

  15. Gracely RH, Lynch SA, Bennett GJ. Painful neuropathy: Altered central processing maintained dynamically by peripheral input. Pain 1992;51:175–94.

    Article  PubMed  CAS  Google Scholar 

  16. Turner MLC, Marinoff SC, Gracely RH. Vulvodynia: Altered central processing maintained dynamically by focal peripheral input. American Pain Society Abstracts 1995.

    Google Scholar 

  17. Merskey H, Bodduk N, editors. Classification of Chronic Pain, 2nd edn. Seattle: IASP Press, 1994.

    Google Scholar 

  18. Gebhart GF. (1997) Pharmacologic agents for chronic pain. In: Vulvodynia Workshop. Bethesda, MD: National Institutes of Health, 68–73.

    Google Scholar 

  19. Foster DC, Hasday JD. Elevated tissue levels of interleukin-1 beta and tumor necrosis factor-alpha in vulvar vestibulitis. Obstet Gynecol 1997;89(2):291–6.

    Article  PubMed  CAS  Google Scholar 

  20. de Groat WC. Neurophysiology of micturition and its modification in animal models of human disease. In: Maggi CA, editor. The Autonomic Nervous System, Vol. 3, Chapter 8, Nervous Control of the Urogenital System. London: Harwood Publishers 1993; 227–347.

    Google Scholar 

  21. Tsigos C, Chrousos GP. Stress, endocrine manifestations and diseases. In: Cooper CL, editor. Handbook of Stress Medicine. Boca Raton, FL: CRC Press, 1995; 61–5.

    Google Scholar 

  22. Chrousos GP. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N Engl J Med 1995;332:1351–62.

    Article  PubMed  CAS  Google Scholar 

  23. Mogil JS, Sternberg WF, Marek P, Sadowski B, Belknap JD, Liebeskind JC. The genetics of pain and pain inhibition. Proc Natl Acad Sci USA 1996;93:3048–55.

    Article  PubMed  CAS  Google Scholar 

  24. Schover LR, Youngs DD, Cannata R. Psychosexual aspects of the evaluation and management of vulvar vestibulitis. Am J Obstet Gynecol 1992;167:630–6.

    PubMed  CAS  Google Scholar 

  25. Stewart DE, Reicher AE, Gerulath AH, Boydell KM. Vulvodynia and psychological distress. Obstet Gynecol 1994;84:587–90.

    PubMed  CAS  Google Scholar 

  26. Slocumb JC, Kellner R, Rosenfeld RC, Pathak D. Anxiety and depression in patients with abnormal pelvic pain syndrome. General Hospital Psychiatry 1989;11:48–53.

    Article  PubMed  CAS  Google Scholar 

  27. McKay M. Vulvodynia: A multifactorial problem. Arch Dermatol 1989;125:256–62.

    Article  PubMed  CAS  Google Scholar 

  28. Watson CP, Evans RJ, Reed K et al. Amitriptyline versus placebo in postherpetic neuralgia. Neurology 1982;32:671.

    PubMed  CAS  Google Scholar 

  29. McKay M. Dysesthetic (‘essential’) vulvodynia. Treatment with amitriptyline. J Reprod Med 1993;38:9–13.

    PubMed  CAS  Google Scholar 

  30. Glazer HI, Rodke G, Swencionis C, Hertz R, Young AW. The treatment of vulvar vestibulitis syndrome by electromyographic biofeedback of pelvic floor musculature. J Reprod Med 1995;40:283–90.

    PubMed  CAS  Google Scholar 

  31. Bergeron S, Binik YM, Khalife S, Pagidas K. Vulvar vestibulitis syndrome: a critical review. Clin J Pain 1997;13(1):27–42.

    Article  PubMed  CAS  Google Scholar 

  32. Solomons CC, Melmed MH, Heitler SM. Calcium citrate for vulvar vestibulitis: a case report. J Reprod Med 1991;36:879–82.

    PubMed  CAS  Google Scholar 

  33. Baggish MS, Sze EH, Johnson R. Urinary oxalate excretion and its role in vulvar pain syndrome. Am J Obstet Gynecol 1997;177(3):507–11.

    Article  PubMed  CAS  Google Scholar 

  34. Sangwan YP, Coller JA, Barrett RC, Murray JJ, Roberts PJ, Schoetz DJ. Unilateral pudendal neuropathy. Dis Colon Rectum 1996;39:249–51.

    Article  PubMed  CAS  Google Scholar 

  35. Alevizon SJ, Finan MA. Sacrospinous colpopexy: management of postoperative pudendal nerve entrapment. Obstet Gynecol 1996;88:713–15.

    Article  PubMed  CAS  Google Scholar 

  36. Monga M, Ghoniem G. Ilioinguinal nerve entrapment following needle bladder suspension procedures. Urology 1994;44:447–50.

    Article  PubMed  CAS  Google Scholar 

  37. McKay M. Vulvodynia: diagnostic patterns. Dermatol Clin 1992;10:423–33.

    Article  PubMed  CAS  Google Scholar 

  38. Clauw DJ. Fibromyalgia: more than just a musculoskeletal disease. Am Fam Phys 1995;52(3):843–51.

    CAS  Google Scholar 

  39. Foster DC, Robinson JC, Davis KM. Urethral pressure variation in women with vulvar vestibulitis. Am J Obstet Gynecol 1993;169:107–12.

    PubMed  CAS  Google Scholar 

  40. Drutz HP, Mainprize TC, Tremblay P. Baker KR. Detrusor sphincter dyssynergia, detrusor instability, and urethral sphincter spasticity as the urodynamic findings in the urethral syndrome: role of treatment with a combined anticholinergic and alpha blocking agent, bladder drill, and antibiotics. Int Urogynecol J 1991;2:10–15.

    Article  Google Scholar 

  41. Clauw DJ. The pathogenesis of chronic pain and fatigue syndromes, with special reference to fibromyalgia. Med Hypothesis 1995;44(5):369–78.

    Article  CAS  Google Scholar 

  42. Pyka RE, Wilkinson EJ, Friedrich EG, Jr, Croker BP. The histopathology of vulvar vestibulitis syndrome. Int J Gynecol Pathol 1988;7(3):249–57.

    Article  PubMed  CAS  Google Scholar 

  43. Furlonge CB, Thin RN, Evans BE, McKee PH. Vulvar vestibulitis syndrome: a clinico-pathological study. Br J Obstet Gynaecol 1991;98:703–6.

    PubMed  CAS  Google Scholar 

  44. Melmed MH, Solomons CC. (1993) Low oxalate diet and calcium citrate for vulvar vestibulitis. Proceedings of the 12th Congress of the ISSVD. Book of Abstracts: 35.

    Google Scholar 

  45. Bornstein J, Goldik Z, Alter Z, Zarfati D, Abramovici H. Persistent vulvar vestibulitis: the continuing challenge. Obstet Gynaecol Surv 1998;53(1):39–44.

    Article  CAS  Google Scholar 

  46. Weijmar Schultz WC, Gianotten WL, van der Meijden WI et al. Behavioural approach with or without surgical intervention to the vulvar vestibulitis syndrome: a prospective randomized and non-randomized study. J Psychosom Obstet Gynaecol 1996;17(3):143–8.

    Article  PubMed  CAS  Google Scholar 

  47. Marinoff SC, Turner ML, Hirsch RP et al. Intralesional alpha interferon: cost-effective therapy for vulvar vestibulitis syndrome. J Reprod Med 1993;38:19.

    PubMed  CAS  Google Scholar 

  48. Masterson BJ, Galask RP, Ballas ZK. Natural killer cell function in women with vestibulitis. J Reprod Med 1996;41(8):562–8.

    PubMed  CAS  Google Scholar 

  49. Chaim W, Meriwether C, Gonik B, Qureshi F, Sobel JD. Vulvar vestibulitis subjects undergoing surgical intervention: a descriptive analysis and histopathological correlates. Eur J Obstet Gynecol Reprod Biol 1996;68(1–2):165–8.

    Article  PubMed  CAS  Google Scholar 

  50. Kehoe S, Luesley D. An evaluation of modified vestibulectomy in the treatment of vulvar vestibulitis: preliminary results. Acta Obstet Gynecol Scand 1996;75(7):676–7.

    Article  PubMed  CAS  Google Scholar 

  51. Foster DC, Butts E, Shah KV, Woodruff JD. Long-term outcome of peri-neoplasty for vulvar vestibulitis. J Women’s Health 1995;4:669–75.

    Google Scholar 

  52. Bergeron S, Bouchard C, Fortier M, Binik YM, Khalife S. The surgical treatment of vulvar vestibulitis syndrome: a followup study. J Sex Marital Ther 1997;23(4):317–25.

    PubMed  CAS  Google Scholar 

  53. Marinoff SC. Surgical treatment of vulvar vestibulitis. In: Vulvodynia Workshop Bethesda, MD: National Institutes of Health, 1997; 28–32.

    Google Scholar 

  54. Bornstein J, Zarfati D, Goldik Z, Abramovici H. Perineoplasty compared with vestibuloplasty for severe vulvar vestibulitis. Br J Obstet Gynaecol 1995;102(8):652–5.

    PubMed  CAS  Google Scholar 

  55. Goetsch MF. Simplified surgical revision of the vulvar vestibule for vulvar vestibulitis. Am J Obstet Gynecol 1996;174(6):1701–5.

    Article  PubMed  CAS  Google Scholar 

  56. Reid R, Omoto KH, Precop SL et al. Flashlamp-excited dye laser therapy of idiopathic vulvodynia is safe and efficacious. Am J Obstet Gynecol 1995;172:1684–701.

    Article  PubMed  CAS  Google Scholar 

  57. Marinoff SC, Turner MLC. Vulvar vestibulitis syndrome. Dermatol Clin 1992;10:435–44.

    PubMed  CAS  Google Scholar 

  58. Davis GD. The management of vulvar vestibulitis syndrome with the carbon dioxide laser. J Gynecol Surg 1989;5:87–91.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. St Michael’s Hospital, Toronto, Ontario, Canada

    Dr Alan H. Gerulath (Associate Professor and Director of Vulvar Clinic)

Authors
  1. Dr Alan H. Gerulath
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Editor information

Editors and Affiliations

  1. Urogynecology Unit, Mount Sinai Hospital, Toronto, Ontario, Canada

    H. P. Drutz BA, MD, FRC(C), FACOG, FSOGC

  2. Division of Urology, University of Toronto, Toronto, Ontario, Canada

    S. Herschorn BSc, MDCM, FRCSC

  3. Division of Gastroenterology, Department of Medicine, University of Toronto, Toronto Hospital, Toronto, Ontario, Canada

    N. E. Diamant MD, FRCP(C)

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© 2003 Springer-Verlag London Limited

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Gerulath, A.H. (2003). Vulvodynia and Vestibulitis. In: Drutz, H.P., Herschorn, S., Diamant, N.E. (eds) Female Pelvic Medicine and Reconstructive Pelvic Surgery. Springer, London. https://doi.org/10.1007/1-84628-238-1_19

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  • DOI: https://doi.org/10.1007/1-84628-238-1_19

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-237-9

  • Online ISBN: 978-1-84628-238-6

  • eBook Packages: Springer Book Archive

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