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Nitric Oxide and Cardiovascular Protection

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The Role of Nitric Oxide in Heart Failure

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Abstract

Nitric oxide (NO) plays a critical role in ischemic heart disease and ischemia-reperfusion. There is an increasing body of evidence to support the role of NO in myocardial and vascular protection in disease. The finding that NO might act as a trigger of late ischemic preconditioning (IPC) might lead to the development of novel anti-ischemic therapy. The role of NO signaling in the cardioprotective effects of ACE inhibitors and angiotensin II type 1 receptor(AT 1 ) receptor antagonists is an active area of study.

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  1. 2C2.43 Walter Mackenzie Health Sciences Centre, Division of Cardiology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada, T6G 2R7

    Dr. Bodh I. Jugdutt

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  1. Cardiology Division Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

    Bodh I. Jugdutt

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Jugdutt, B.I. (2004). Nitric Oxide and Cardiovascular Protection. In: Jugdutt, B.I. (eds) The Role of Nitric Oxide in Heart Failure. Springer, Boston, MA. https://doi.org/10.1007/1-4020-7960-5_11

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  • DOI: https://doi.org/10.1007/1-4020-7960-5_11

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