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Immunity, Inflammation and infections during aging

  • Miriam Capri
  • Stefano Salvioli
  • Federica Sevini
  • Elisa Cevenini
  • Michela Pierini
  • Laura Celani
  • Laura Bucci
  • Rita Ostan
  • Maria Scurti
  • Daniela Mazza
  • Daniela Monti
  • Claudio Franceschi
Chapter
  • 919 Downloads

Abstract

The major changes occurring life long in the human immune system are here described. The progressive inflammatory status which is established during aging together with the progressive susceptibility to infectious diseases are discussed in the frame of the genetic variant influence. Finally, the possibility to counteract the susceptibility to infections by coping with or slowing down immunosenescence, using different molecules or strategies, is argued

Keywords

aging cytokines immunity inflammation macrophage T lymphocyte infectious genes anti-immunosenescence 

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Copyright information

© Springer 2006

Authors and Affiliations

  • Miriam Capri
    • 1
    • 2
  • Stefano Salvioli
    • 1
    • 2
  • Federica Sevini
    • 1
    • 2
  • Elisa Cevenini
    • 1
    • 2
  • Michela Pierini
    • 1
    • 2
  • Laura Celani
    • 1
    • 2
  • Laura Bucci
    • 3
  • Rita Ostan
    • 1
  • Maria Scurti
    • 1
    • 2
  • Daniela Mazza
    • 1
    • 2
  • Daniela Monti
    • 3
  • Claudio Franceschi
    • 1
    • 2
    • 4
  1. 1.Department of Experimental PathologyUniversity of Bologna
  2. 2.CIGInterdepartmental Center GalvaniVia S. GiacomoUniversity of Bologna
  3. 3.Department of Experimental Oncology and PathologyVia Morgagni50
  4. 4.INRCANational Institute for Research on AgingVia Birarelli 8Italy

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