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SUPPRESSION OF SYNAPTIC TRANSMISSION IN HIPPOCAMPUS BY EXTREMELY-HIGH POWER MICROWAVE PULSES SYNCHRONIZED WITH NEURONAL EXCITATION

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BIOELECTROMAGNETICS Current Concepts

Part of the book series: NATO Security Through Science Series ((NASTB))

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Abstract

Our previous research of bioeffects of extremely high power pulses (EHPP) in excitable tissues (isolated brain and heart slices) did not reveal any specific effects of this radiation modality. In this study, we explored if EHPP may cause different effects when they are applied in synchronism with membrane excitation events. The experiments were performed in rat hippocampal slices. Excitatory postsynaptic potentials (EPSPs) in CA1 field were evoked by twin pulse stimulation of Schaffer collateral (20 ms interpulse interval, 1 pair/15 sec) and recorded extracellularly with a glass micropipette (2-8 Mohm).

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Author information

Authors and Affiliations

  1. McKesson BioServices Corporation, Brooks City Base, San Antonio, TX, USA

    JOANNE DOYLE

  2. US Army Medical Research Detachment, Brooks City Base, San Antonio, TX, USA

    BRUCE STUCK

  3. Directed Energy Bioeffects Division Human Effectiveness Directorate Air Force Research Laboratory, Brooks City Base, San Antonio, TX, USA

    MICHAEL R. MURPHY

  4. Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA

    ANDREI G. PAKHOMOV

Authors
  1. JOANNE DOYLE
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  2. BRUCE STUCK
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  3. MICHAEL R. MURPHY
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  4. ANDREI G. PAKHOMOV
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Editor information

Editors and Affiliations

  1. UNESCO Chair - Life Sciences International, Postgraduate Educational Center, Yerevan, Armenia

    Sinerik N. Ayrapetyan

  2. Research International, Buffalo Office, Williamsville, Buffalo, NY, U.S.A.

    Marko S. Markov

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© 2006 Springer

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DOYLE, J., STUCK, B., MURPHY, M.R., PAKHOMOV, A.G. (2006). SUPPRESSION OF SYNAPTIC TRANSMISSION IN HIPPOCAMPUS BY EXTREMELY-HIGH POWER MICROWAVE PULSES SYNCHRONIZED WITH NEURONAL EXCITATION. In: Ayrapetyan, S.N., Markov, M.S. (eds) BIOELECTROMAGNETICS Current Concepts. NATO Security Through Science Series. Springer, Dordrecht . https://doi.org/10.1007/1-4020-4278-7_6

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  • DOI: https://doi.org/10.1007/1-4020-4278-7_6

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-1-4020-4276-8

  • Online ISBN: 978-1-4020-4278-2

  • eBook Packages: MedicineMedicine (R0)

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