PARTICULARITIES IN RESEARCH, PRODUCTION AND ACQUISITION OF THE PHARMACEUTICAL PRODUCTS FOR NBC MEDICAL PROTECTION

Abstract

Medical research is a branch of biological research, as a fundamental area of scientific research. The results of medical research could be pharmaceutical products, diagnosis methods, surgical or investigational techniques, that are used for medical protection in an NBC environment. The main fields covered by biomedical research in NBC protection are: toxicology, radiobiology, microbiology, pharmacology, pharmaceutical techniques, internal medicine etc. New drugs and vaccines, diagnosis, treatment and prophylaxis methods are the final results of these activities. Rarely, depending on the level of technological development, there is research in the field equipment for pathogens or noxious chemicals identification. The steps required to obtain a new pharmaceutical products are many and often very difficult to go through. The first step is biochemical synthesis of the experimental product, followed by preclinical experiments. These include “in vitro” tests and experiments on laboratory animals that could be forbidden by law, especially if they kill the animal. A very sensitive step is clinical experiment. This supposes to follow all legal aspects regarding experiments on human beings. Also teratogenic, oncogenic, citotoxic effects must be identified, in order to avoid harmful effects on the treated persons. The minimum time to introduce a new drug or vaccine in the medical practice is about ten years. In the biomedical research for NBC pharmaceutical products a very important issue is to find the producer and the funds for them. Due to such difficulties these products are named “orphan products”. This very important aspects requires the involvement of government and public authorities, because the lack of “orphan products” is followed by losses of human lives.