Abstract
The present article reviews three different optical biosensing mechanisms that can be implemented in a multibiosensor technology platform: surface plasmon resonance, magnetooptical surface plasmon resonance and optoelectronic biosensing (evanescent wave detection) using integrated Mach-Zehnder interferometer devices. In the last case, the use of standard silicon microelectronics technology opens the possibility for integration of optical, fluidics based and electrical functions within a single optical sensing circuit leading to a complete lab-on-a-chip design solution. All three mechanisms can be efficiently used as an early warning system for biological and/or chemical warfare.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
REFERENCES
M. D. Wheeler, Photonics on the Battlefield, Photonics Spectra, 124-132 (1999).
R. A. Lewis, Microarrays take on bioterrorism, Biophotonics International, Jan/Feb, 40-41 (2002)
E. Croddy, C. Perez-Armendariz and J. Hart, (Eds.), Chemical and Biological Warfare, (Copernicus Books, Springer-Verlag, New York, 2002).
S. S. Iqbal, M. W. Mayo, J. G. Bruno, B. V. Bronk, C.A. Batt and J. P. Chambers, A review of molecular recognition technologies for detection of biological threat agents, Biosens & Bioelec 15, 459-578 (2000).
C. A. Rowe-Taitt, J.W. Hazzard, K.E. Hoffman, J.L. Cras, J.P. Golden and F.S. Ligler, Simultaneous detection of six biohazardous agents using a planar waveguide array biosensor, Biosens. & Bioelec. 15, 579-589 (2000).
F. S. Liegler and C.R. Taitt, (Eds), Optical Biosensors: Present and future (Elsevier, Amsterdam, Netherlands, 2002).
L. M. Lechuga, F. Prieto and B. Sepúlveda, Interferometric Biosensors for environmental pollution detection, in Optical Sensors for Industrial, Environmental and Clinical Applications, Springer Series on Chemical Sensors and Biosensors, Vol. 1, (Springer Verlag, New York, 2003).
L. M. Lechuga, Optical Biosensors, in Biosensors and Modern Biospecific Analytical Techniques, Comprehensive Analytical Chemistry Series, L. Gorton, Ed., (Elsevier Science BV, Amsterdam, Netherlands, 2005).
R. L. Rich and D.G. Myszka, Spying on HIV with SPR, Trends in Microbiology 11, 124-133 (2003).
G. C. Nenninger, M. Piliarik and J. Homola, Data analysis for optical sensors based on spectroscopy of surface plasmons, Meas. Sci. Technol. 13 2038-2046 (2002).
R. P. H. Kooyman and L.M. Lechuga, in Handbook of Biosensors: Medicine, Food and the Environment, E. Kress-Rogers (Ed.) (CRC Press, Florida, USA, 1997) 169-196.
J. Homola, S. Yee and D. Myszka, Surface Plasmon Biosensors, in F. S. Liegler and C. R. Taitt (Eds), Optical Biosensor : Present and future (Elsevier, Amsterdam, Netherlands, 2002).
J. Homola, Present and future of surface plasmon resonance biosensors, Anal. Bioanal. Chem 377, 528-539 (2003).
R. L. Rich and D. G. Myszka, Advance in surface plasmon resonance biosensor analysis, Current Opinion in Biotechnology 11 54-61 (2000).
R. L. Rich and D. G. Myszka, Survey of the year 2003 commercial optical biosensor literature, J. Mol. Recognit. 18, 1-39; 273-294 (2005).
A. E. Botchkareva, F. Fini, S. Eremin, J. V. Mercader, A. Montoya, S. Girotti, Development of a heterogeneous chemiluminescent flow immunoassay for DDT and related compounds, Anal. Chim. Acta, 43-52 (2002).
www.sensia.es
Patent application P200401437.
D.P. Campbell and J. McCloskey, Interferometric Biosensor, In “Optical Biosensors: present and future”. Ed. F. Liegler and C.Rowe, (Elsevier, Amsterdam, Netherlands, 2002), 277-304.
R. G. Heideman and P. V. Lambeck, Remote opto-chemical sensing with extreme sensitivity: design, fabrication and performance of a pigtailed integrated optical phase-modulated Mach-Zehnder interferometer system, Sensors and Actuators B 61, 100-127 (1999).
F. Prieto, A. Llobera, A. Calle, C Domínguez and L.M. Lechuga, Design and analysis of silicon antiresonant reflecting optical waveguides for highly sensitive sensors, J. Lightwave Tech. 18(7), 966-972 (2000).
F. Prieto, B. Sepúlveda, A. Calle, A. Llobera, C. Domínguez, A. Abad, A. Montoyaand L.M. Lechuga, An integrated Optical interferometric Nanodevice based on silicon technology for biosensor applications, Nanotechnology 14, 907 (2003).
F. Prieto, L. M. Lechuga, A. Llobera, A. Calle and C Domínguez, Optimised Silicon Antiresonant Reflecting Optical Waveguides for Sensing Applications. J. of Lightwave Tech. 19(1), 75-83 (2001).
F. Prieto, B. Sepúlveda, A. Calle, A. Llobera, C. Domínguez and L.M. Lechuga, Integrated Mach-Zehnder Interferometer based on ARROW structures for biosensor applications, Sensors and Actuators B 92, 151-158 (2003).
C. Domínguez, L.M. Lechuga and J.A. Rodríguez, Integrated optical chemo-and Biosensors, in Integrated Analytical Systems, S. Alegret (Ed.) (Elsevier Science BV, Amsterdam, Netherlands, 2003).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer
About this paper
Cite this paper
Lechuga, L. et al. (2006). OPTICAL BIOSENSOR DEVICES AS EARLY DETECTORS OF BIOLOGICAL AND CHEMICAL WARFARE AGENTS. In: Janz, S., Ctyroky, J., Tanev, S. (eds) Frontiers in Planar Lightwave Circuit Technology. NATO Science Series II: Mathematics, Physics and Chemistry, vol 216. Springer, Dordrecht. https://doi.org/10.1007/1-4020-4167-5_05
Download citation
DOI: https://doi.org/10.1007/1-4020-4167-5_05
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-4164-8
Online ISBN: 978-1-4020-4167-9
eBook Packages: Physics and AstronomyPhysics and Astronomy (R0)