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Is Type 1 Diabetes a Disease of the Gut Immune System Triggered by Cow’s Milk Insulin?

  • Outi Vaarala
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 569)

Abstract

The role of the gut immune system in the development of autoimmune m type 1 diabetes is evaluated in this review with special emphasis in the hypothesis suggesting that dietary cow’s milk insulin could trigger betacell autoimmunity when the mechanisms of oral tolerance are disturbed.

Key words

type 1 diabetes insulin gut beta-cell autoimmunity alpha4beta7-integrin cytokines breast milk microflora enterovirus 

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Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  • Outi Vaarala
    • 1
  1. 1.Department of Molecular and Clinical Medicine, Faculty of Health SciencesUniversity of LinköpingSweden

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