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Rho Proteins and Vesicle Trafficking

  • Chapter
RHO Family GTPases

Part of the book series: Proteins and Cell Regulation ((PROR,volume 3))

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Abstract

Membrane trafficking includes a highly dynamic and intricate set of intracellular pathways responsible for the transport of molecules in and out of the cell, and between the different intracellular compartments. A lot of attention has been paid in the past decades to the role played by distinct classes of small GTPases on the regulation of membrane trafficking, with special emphasis on the Rab and Arf families. More recently, Rho GTPases have been implicated in several important aspects of membrane trafficking. The initial indications that Rho proteins might be involved in membrane trafficking came from the observation of the localization of some of these proteins at specific intracellular compartments. These observations are corroborated by the findings of specific effects of these proteins on different membrane transport pathways. The role played by Rho family members in different aspects of membrane trafficking will be considered in this chapter.

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Authors and Affiliations

  1. Cell Adhesion Laboratory, San Raffaele Scientific Institute, Milano, Italy

    Ivan De Curtis

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  1. Ivan De Curtis
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  1. Institute of Molecular and Cell Biology, Singapore

    Ed. Manser (Principle Investigator) (Principle Investigator)

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© 2005 Springer

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De Curtis, I. (2005). Rho Proteins and Vesicle Trafficking. In: Manser, E. (eds) RHO Family GTPases. Proteins and Cell Regulation, vol 3. Springer, Dordrecht. https://doi.org/10.1007/1-4020-3462-8_9

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