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References
Robson, M.C.; Barnett, R.A.; Leitch, I.O. and Hayward, P.G. (1992) Prevention and treatment of postburn scars and contracture. World J. Surg. 16: 87–96.
McHugh, A.A.; Fowlkes, B.J.; Maevsky, E.I.; Smith, D.J. Jr.; Rodriguez, J.L. and Garner, W.L. (1997) Biomechanical alterations in normal skin and hypertrophic scar after thermal injury. J. Burn Care Rehabil. 18: 104–108.
Mast, B.A and Newton, E.D. (1996) Aggressive use of free flaps in children for burn scar contractures and other soft-tissue deficits. Ann. Plast. Surg. 36: 569–575.
Isenberg, J.S. and Price, G. (1996) Longitudinal trapezius fasciocutaneous flap for the treatment of mentosternal burn scar contractures. Burns 22: 76–79.
Asmursen, P.D. (1986) Einfurung and Grundlage: Rohstoffe, Die Hant, Klebetchnologie, Hamburg Ag. Compendium Medical, Berlin: Hamburg, Biersdorf, vol. 1.
Mast, B.A. (1992) The skin. In: Cohen, I.K.; Diegelmann, R.F. and Lindbald, W.J. (Eds.) Wound healing: biochemical and clinical aspects, W.B. Saunders, Philadelphia, USA; pp. 344–355.
Clark, R.A.F. and Henson, P.M. (1988) The molecular and cellular biology of wound repair. Plenum Press, New York, USA.
Jennings, R.W. and Hung, T.K. (1992) In: Adzick, N.S. and Longacker, M.T. (Eds.) Fetal wound healing. Elsevier, New York, USA; pp. 25.
Calvin, M. (1998) Cutaneous wound repair Wounds. A Compendium of Clinical Research and Practice 12, pp. 32.
Gallico, G.G. 3rd.; O’Connor, N.E.; Compton, C.C.; Kehinde, O. and Green, H. (1984) Permanent coverage of large burn wounds with autologous cultured human epithelium. N. Engl. J. Med. 311(7): 448–51.
Limova, M. and Mauro, T. (1995) Treatment of leg ulcers with cultured epithelial autografts: clinical study and case reports. Ostomy Wound Manage 41(8): 48–50, 52, 54–60.
Pruitt, B.A. Jr. and Levine, S. (1984) Characteristics and uses of biologic dressings and skin substitutes. Arch. Surg. 199: 312–322.
Hansbrough, J.F. (1992) Wound coverage with biologic dressings and cultured skin substitutes. Landes, Austin, USA.
Odessey, R. (1992) Addendum: Multicenter experience with cultured epithelial autografts for treatment of burns. J. Burn Care Rehabil. 13: 174–180.
Pittelkow, M.R. and Scott, R.E. (1986) New techniques for the in vitro culture of human skin keratinocytes and perspectives on their use for grafting of patients with extensive burns. Mayo Clin. Proc. 61: 771–777.
Boyce, S.T.; Greenhalgh, D.G.; Kagan, R.J.; Housinger, T.; Sorrell, J.M.; Childress, C.P.; Rieman, M. and Warden, G.D. (1993) Skin anatomy and antigen expression after burn wound closure with composite grafts of cultured skin cells and biopolymers. Plast. Reconstr. Surg. 91: 632–641.
Desai, M.H.; Mlakar, J.M.; McCauley, R.L.; Abdullah, K.M.; Rutan, R.L.; Waymack, J.P.; Robson, M.C. and Herndon, D.N. (1991) Lack of long term durability of cultured keratinocyte burn wound coverage: a case report. J. Burn Care Rehabil. 12: 540–545.
Williamson, J.S.; Snelling, C.F.; Clugston, P.; Macdonald, I.B. and Germann, E. (1995) Cultured epithelial autograft: Five years of clinical experience with twenty-eight patients. J. Trauma 39: 309–319.
Rue, L.W.; Cioffi, W.G.; McManus, W.F. and Pruitt, B.A. Jr. (1993) Wound closure and outcome in extensively burned patients treated with cultured autologous keratinocytes. J. Trauma 34: 662–667.
Boyce, S.T. and Warden G.D. (2002) Principles and practices for treatment of cutaneous wounds with cultured skin substitutes. Am. J. Surg. 183: 445–456.
Coulomb, B. and Dubertret, L. (2002) Skin cell culture and wound healing. Wound Rep. Regen. 10:109.
Rennekampff, H.O.; Kiessig, V. and Hansbrough, J.F. (1996) Current concepts in the development of cultured skin replacements. J. Surg. Res. 62(2): 288–295.
Rennekampff, H.O.; Kiessig, V.; Griffey, S.; Greenleaf, G. and Hansbrough, J.F. (1997) Acellular human dermis promotes cultured keratinocyte engraftment. J. Burn Care Rehabil. 18(6): 535–544.
Oksala, O.; Salo, T.; Tammi, R.; Hakkinen, L.; Jalkanen, M.; Inki, P. and Larjava, H. (1995) Expression of proteoglycans and hyaluronan during wound healing. J. Histochem. Cytochem. 43(2): 125–135.
Zacchi, V.; Soranzo, C.; Cortivo, R.; Radice, M.; Brun, P. and Abatangelo, G. (1998) In vitro engineering of human skin-like tissue. J. Biomed. Mater. Res. 40(2): 187–194.
Fusenig, N.E.; Limat, A.; Stark, H.J. and Breitkreutz, D. (1994) Modulation of the differentiated phenotype of keratinocytes of the hair follicle and from epidermis. J. Dermatol. Sci. Jul. 7 suppl. S142–151.
Lamme, E.N.; de Vries, H.J.; van Veen, H.; Gabbiani, G.; Westerhof, W. and Middelkoop, E. (1996) Extracellular matrix characterization during healing of full-thickness wounds treated with a collagen/elastin dermal substitute shows improved skin regeneration in pigs. J. Histochem. Cytochem. 44(11): 1311–1322.
Falanga, V. (1998) Apligraf treatment of venous ulcers and other chronic wounds. J. Dermatol. 25(12): 812–817.
Falanga, V.; Margolis, D.; Alvarez, O.; Auletta, M.; Maggiacomo, F.; Altman, M.; Jensen, J.; Sabolinski, M. and Hardin-Young, J. (1998) Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent. Human Skin Equivalent Investigators Group. Arch. Dermatol. 134: 293–300.
Galassi, G.; Brun, P.; Radice, M.; Cortivo, R.; Zanon, G.F.; Genovese, P. and Abatangelo, G. (2000) In vitro reconstructed dermis implanted in human wounds: degradation studies of the HA-based supporting scaffold. Biomaterials 21(21): 2183–91.
Cuono, C.B.; Langdon, R.; Birchall, N.; Barttelbort, S. and McGuire, J. (1987) Composite autologous-allogenic skin replacement: development and clinical application. Plast. Reconstr. Surgery 80: 626–35.
Compton, C.C.; Gill, J.F.; Bradford, D.A.; Regauer, S.; Gallico, G.G. and O’Connor, N.E. (1989) Skin regenerated from cultured epithelial autografts on full-thickness burn wounds from 6 days to 5 years after grafting. Lab. Invest. 60: 600–612.
Neveux, Y.; Rives, J.M.; Lebreton, C.; Gentilhomme, E.; Saint-Blancar, P. and Carsin, M. (1995) Clinical interest of cutaneous models reproduced in vitro for severeburn treatment: histopathologic and ultrastructural study. Cell Biol. Toxicol. 11: 173–178.
Sher, S.E.; Hull, B.E.; Rosen, S.; Church, D.; Friedman, L. and Bell, E. (1983) Acceptance of allogeneic fibroblasts in skin equivalent transplants. Transplant. 36: 5052–5057.
Sorrell, J.M.; Carrino, D.A.; Baber, M.A.; Asselinean, D. and Caplan, A.I. (1999) A monoclonal antibody recognizes a glycosaminoglycan epitope in both dermatan sulfate and chondroitin sulfate proteoglycans of human skin. Histochem. J. 31: 549–558.
Prockop, D. (1997) Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276: 71–74.
Bucala, R.; Spiegel, L.; Chesney, J.; Hogan, M. and Cerami, A. (1994) Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol. Med. 1: 71–81.
Leigh, I.M.; Purkis, P.E.; Navsaria, H.A.; Phillips, T.J. (1987) Treatment of chronic venous ulcers with sheets of cultured allogenic keratinocytes. Br. J. Dermatol. 117: 591–597.
De Luca, M.; D’Anna, F.; Bondanza, S.; Franzi, A.T. and Cancedda, R. (1992) Treatment of leg ulcers with cryopreserved allogeneic cultured epithelium — a multicenter study. Arch. Dermatol. 28: 633–638.
Mol, M.A.; Nanninga, P.B.; van Eendenburg, J.P.; Westerhof, W.; Mekkes, J.R. and van Ginkel, C.J. (1991) Grafting of venous leg ulcers. An intraindividual comparison between cultured skin equivalents and full-thickness skin punch grafts. J. Am. Acad. Dermatol. 24: 77–82.
Teepe, R.G.; Koebrugge, E.J.; Ponec, M. and Vermeer, B.J. (1990) Fresh versus cryopreserved cultured allografts for the treatment of chronic skin ulcers. Br. J. Dermatol. 122: 81–89.
Teepe, R.G.; Roseeuw, D.I.; Hermans, J.; Koebrugge, E.J.; Altena, T.; de Coninck, A.; Ponec, M. and Vermeer, B.J. (1993) Randomized trial comparing cryopreserved cultured epidermal allografts with hydrocolloid dressings in healing chronic venous ulcers. J. Am. Acad. Dermatol. 29: 982–988.
Phillips, T.J.; Kehinde, O.; Green, H. and Gilchrest, B.A. (1989) Treatment of skin ulcers with cultured epidermal allografts. J. Am. Acad. Dermatol. 21: 191–199.
Gilchrest, B.A. (1983) In vitro assessment of keratinocyte aging. J. Invest. Dermatol. 81: 184s–189s.
Trent, J.F. and Kirsner, R.S. (1998) Tissue engineered skin: Apligraf, a bi-layered living skin equivalent. Int. J. Clin. Pract. 52: 408–413.
Parenteau, N.L. (1998) Skin equivalents, In: Leigh, I.M. and Watt, F.M. (Eds.) Keratinocytes methods. Cambridge University Press, London; pp. 44–55.
Eaglstein, W.H. and Falanga, V. (1998) Tissue engineering and the development of Apligraft a human skin equivalent. Adv. Wound Care 11: 1–8.
Eaglstein, W.H.; Iriondo, M. and Laszlo, K. (1995) A composite skin substitute (graftskin) for surgical wounds. A clinical experience. Dermatol. Surg. 10: 839–843.
Yannas, I.V.; Burke, J.F.; Gordon, P.L.; Huang, C. and Rubenstein, R.H. (1980) Design of an artificial skin. II. Control of chemical composition. J. Biomed. Mater. Res. 14: 107–132.
Burke, J.F. (1987) Observations on the development and clinical use of artificial skin-an attempt to employ regeneration rather than scar formation in wound healing. Jpn. J. Surg. 17: 431–438.
Bruke, J.F. (1984) The effects of the configuration of an artificial extracellular matrix on the development of a functional dermis. In: Trelstad, R. (Ed.) The role of extracellular matrix in development, Liss, New York; pp. 351–355.
Purdue, G.F.; Hunt, J.L.; Still, J.M. Jr.; Law, E.J.; Herndon, D.N.; Goldfarb, I.W.; Schiller, W.R.; Hansbrough, J.F.; Hickerson, W.L.; Himel, H.N.; Kealey, G.P.; Twomey, J.; Missavage, A.E.; Solem, L.D.; Davis, M.; Totoritis, M. and Gentzkow, G.D. (1997) A multicenter clinical trial of a biosynthetic skin replacement, Dermagraft-TC, compared with cryopreserved human cadaver skin for temporary coverage of excised burn wounds. J. Burn Care Rehabil. 18: 52–57.
Hansbrough, J.F.; Mozingo, D.W.; Kealey, G.P.; Davis, M.; Gidner, A. and Gentzkow, G.D. (1997) Clinical trials of a biosynthetic temporary skin replacement, Dermagraft Transitional Covering, compared with cryopreservedhuman cadaver skin for temporary coverage of excised burn wounds. J. Burn Care Rehabil. 18: 43–51.
Purdue, G.F. (1996) Dermagraft-TC pivotal safety and efficacy study. J. Burn Care Rehabil. 18: 513–514.
Haeri, A.; Clay, J. and Finely, J.M. (1999) Compend Contin Educ The use of an acellular dermal skin graft to gain keratinized tissue. Dent. 1999 20(3): 233–234, 239–242 (quiz 244).
Schwartz, S. (1997) In: A new composite cultured skin product for treatment of burns and other deep dermal injuries. Presented at the Bioengineering of Skin Substitutes Conference. Boston, Mass. (USA); pp. 19.
Beumer, G.J.; van Blitterswijk, C.A.; Bakker, D. and Ponec, M. (1993) A new biodegradable matrix as part of a cell seeded skin substitute for the treatment of deep skin defects: a physico-chemical characterisation. Clin. Mater. 14(1): 21–27.
Noordenbos, J.; Dore, C. and Hansbrough, J.F. (1999) Safety and efficacy of TransCyte for the treatment of partial-thickness burns. J. Burn Care Rehabil. 20(4): 275–281.
Chen, W.Y.J. and Abatangelo, G. (1999) The functions of Hyaluronan in wound repair. Wound Rep. Reg. 7: 79–89.
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Zavan, B., Cortivo, R., Brun, P., Tonello, C., Abatangelo, G. (2005). Bioartificial Skin. In: Nedović, V., Willaert, R. (eds) Applications of Cell Immobilisation Biotechnology. Focus on Biotechnology, vol 8B. Springer, Dordrecht. https://doi.org/10.1007/1-4020-3363-X_3
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