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ARF Family GTPases pp 241–257Cite as

Coat Proteins

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Part of the book series: Proteins and Cell Regulation ((PROR,volume 1))

Abstract

A major cellular function of Arfs is the regulation of membrane traffic. Many studies, using several independent approaches, have shown that activated Arfs directly recruit coat complexes to membranes. These coats sort cargo and facilitate vesicle formation. Three classes of Arf-dependent coat proteins or complexes have been described so far, including COPs, adaptins, and GGAs. This chapter focuses on aspects of Arf-dependent coat proteins and complexes. We will discuss the binding between Arfs and coats, with an emphasis on COPI and GGAs, as well as the localization and function of each coat.

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, University of Minnesota School of Medicine Duluth, Duluth, USA

    Annette Boman

  2. European Molecular Biology Laboratory Heidelberg, Heidelberg, Germany

    Tommy Nilsson

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  1. Annette Boman
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Boman, A., Nilsson, T. (2004). Coat Proteins. In: ARF Family GTPases. Proteins and Cell Regulation, vol 1. Springer, Dordrecht. https://doi.org/10.1007/1-4020-2593-9_12

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  • DOI: https://doi.org/10.1007/1-4020-2593-9_12

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