Summary
In this chapter we have focused on elementary interactions in tissue and tumor growth. In particular, CA models for contact inhibition and chemotactic interaction have been presented. Later we showed how different modeling modules can be combined in order to produce a model for the avascular tumor growth phase that can be analyzed in multicellular spheroids. The LGCA model is hybrid: it represents biological cells as discrete entities and molecular concentrations as continuous states.
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© 2005 Birkhäuser Boston
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(2005). Tissue and Tumor Development. In: Cellular Automaton Modeling of Biological Pattern Formation. Modeling and Simulation in Science, Engineering and Technology. Birkhäuser Boston. https://doi.org/10.1007/0-8176-4415-6_10
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DOI: https://doi.org/10.1007/0-8176-4415-6_10
Publisher Name: Birkhäuser Boston
Print ISBN: 978-0-8176-4281-5
Online ISBN: 978-0-8176-4415-4
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