Advertisement

Dipeptidyl Peptidase IV: A Molecular Switch of Vascular Actions of Neuropeptide Y

  • Lijun Li
  • Hans-Ulrich Demuth
  • Zofia Zukowska
Part of the Advances in Experimental Medicine and Biology book series (volume 575)

Keywords

Vascular Smooth Muscle Cell Endothelial Cell Migration Dipeptidyl Peptidase Vascular Smooth Muscle Cell Proliferation Small Resistance Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Ghersi G, Chen W-T, Zukowska Z, 2000, Critical role of dipeptidyl peptidase IV in neuropeptide Y-mediated endothelial cell migration in response to wounding. Peptides. submitted.Google Scholar
  2. Grouzmann E, Comoy E, Bohuon C, 1989, Plasma neuropeptide Y concentrations in patients with neuroendocrine tumors. J Clin Endocrinol Metab. 68: 808–813.PubMedCrossRefGoogle Scholar
  3. Grundemar L, Hakanson R, 1993, Multiple neuropeptide Y receptors are involved in cardiovascular regulation. Peripheral and central mechanisms. Gen Pharmacol. 24: 785–796.PubMedGoogle Scholar
  4. Kitlinska J, Lee EW, Movafagh S, Pons J, Zukowska Z, 2002, Neuropeptide Y-induced angiogenesis in aging. Peptides. 23: 71–77.CrossRefPubMedGoogle Scholar
  5. Kitlinska J, Lee EW, Li L, Pons J, Estes L, Zukowska Z, 2003, Dual role of dipeptidyl peptidase IV (DPP IV) in angiogenesis and vascular remodeling. Adv Exp Med Biol. 524: 215–222.PubMedCrossRefGoogle Scholar
  6. Koulu M, Movafagh S, Tuohimaa J, Jaakkola U, Kallio J, Pesonen U, Geng Y, Karvonen MK, Vainio-Jylha E, Pollonen M, Kaipio-Salmi K, Seppala H, Lee EW, Higgins RD, Zukowska Z, 2004, Neuropeptide Y and Y2-receptor are involved in development of diabetic retinopathy and retinal neovascularization. Ann Med. 36: 232–240.CrossRefPubMedGoogle Scholar
  7. Lee EW, Michalkiewicz M, Kitlinska J, Kalezic I, Switalska H, Yoo P, Sangkharat A, Ji H, Li L, Michalkiewicz T, Ljubisavljevic M, Johansson H, Grant DS, Zukowska Z, 2003, Neuropeptide Y induces ischemic angiogenesis and restores function of ischemic skeletal muscles. J Clin Invest. 111: 1853–1862.CrossRefPubMedGoogle Scholar
  8. Li J, Wilk E, Wilk S, 1995, Aminoacylpyrrolidine-2-nitriles: potent and stable inhibitors of dipeptidyl-peptidase IV (CD 26). Arch Biochem Biophys. 323: 148–154.CrossRefPubMedGoogle Scholar
  9. Li L, Lee EW, Ji H, Zukowska Z, 2003, Neuropeptide Y-Induced Acceleration of Postangioplasty Occlusion of Rat Carotid Artery. Arterioscler Thromb Vasc Biol. 23: 1204–1210.CrossRefPubMedGoogle Scholar
  10. Lewandowski J, Pruszczyk P, Wocial B, Ignatowska-Switalska H, Romejko-Woniewicz E, Madej-Firek A, Januszewicz W, Zukowska-Grojec Z, 1996, Sex hormone modulation of neuropeptide Y and cardiovascular responses to stress in humans. In: McCarty R, Aguilera G, Sabban E, Kvetnansky R, eds. Stress: Molecular and Neurobiological Advances. New York, USA: Gordon and Breach Science Publishers S.A. pp. 569–578.Google Scholar
  11. Myers AK, Farhat MY, Vaz CA, Keiser HR, Zukowska-Grojec Z, 1988, Release of immunoreactive-neuropeptide Y by rat platelets. Biochem Biophys Res Commun. 155: 118–122.CrossRefPubMedGoogle Scholar
  12. Oravecz T, Pall M, Roderiquez G, Gorrell MD, Ditto M, Nguyen NY, Boykins R, Unsworth E, Norcross MA, 1997, Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage. J Exp Med. 186: 1865–1872.CrossRefPubMedGoogle Scholar
  13. Pons J, Kitlinska J, Ji H, Lee EW, Zukowska Z, 2003, Mitogenic actions of neuropeptide Y in vascular smooth muscle cells: synergetic interactions with the beta-adrenergic system. Can J Physiol Pharmacol. 81: 177–185.CrossRefPubMedGoogle Scholar
  14. Qureshi NU, Dayao EK, Shirali S, Zukowska-Grojec Z, Hauser GJ, 1998, Endogenous neuropeptide Y mediates vasoconstriction during endotoxic and hemorrhagic shock. Regul Pept. 75–76: 215–220.CrossRefPubMedGoogle Scholar
  15. von Horsten S, Ballof J, Helfritz F, Nave H, Meyer D, Schmidt RE, Stalp M, Klemm A, Tschernig T, Pabst R, 1998, Modulation of innate immune functions by intracerebroventricularly applied neuropeptide Y: dose and time dependent effects. Life Sci. 63: 909–922.CrossRefGoogle Scholar
  16. Wahlestedt C, Hakanson R, Vaz CA, Zukowska-Grojec Z, 1990, Norepinephrine and neuropeptideY: vasoconstrictor cooperation in vivo and in vitro. Am J Physiol. 258: R736–742.PubMedGoogle Scholar
  17. Zukowska-Grojec Z, Shen GH, Capraro PA, Vaz CA, 1991, Cardiovascular, neuropeptideY, and adrenergic responses in stress are sexually differentiated. Physiol Behav. 49: 771–777.CrossRefPubMedGoogle Scholar
  18. Zukowska-Grojec Z, Pruszczyk P, Colton C, Yao J, Shen GH, Myers AK, Wahlestedt C, 1993, Mitogenic effect of neuropeptide Y in rat vascular smooth muscle cells. Peptides. 14: 263–268.CrossRefPubMedGoogle Scholar
  19. Zukowska-Grojec Z, Wahlestedt C, 1993, Origin and actions of neuropeptide Y in the cardiovascular system. In: Colmers WF, Wahlestedt C, eds. The Biology of Neuropeptide Y and Related Peptides. Totowa, New Jersey: Human Press; pp. 315–388.CrossRefGoogle Scholar
  20. Zukowska-Grojec Z, 1995, Neuropeptide Y. A novel sympathetic stress hormone and more. Ann NY Acad Sci. 771: 219–233.PubMedGoogle Scholar
  21. Zukowska-Grojec Z, Dayao EK, Karwatowska-Prokopczuk E, Hauser GJ, Doods HN, 1996, Stress-induced mesenteric vasoconstriction in rats is mediated by neuropeptide Y Y1 receptors. Am J Physiol. 270: H796–H800.PubMedGoogle Scholar
  22. Zukowska-Grojec Z, 1997, Neuropeptide Y: Implications in vascular remodeling and novel therapeutics. Drug News and Perspectives. 10: 587–595.Google Scholar
  23. Zukowska-Grojec Z, Karwatowska-Prokopczuk E, Rose W, Rone J, Movafagh S, Ji H, Yeh Y, Chen WT, Kleinman HK, Grouzmann E, Grant DS, 1998, Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium. Circ Res. 83: 187–195.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Lijun Li
    • 2
  • Hans-Ulrich Demuth
    • 1
  • Zofia Zukowska
    • 2
  1. 1.ProbiodrugHalleGermany
  2. 2.Department of Physiology and BiophysicsGeorgetown University Medical CenterWashingtonUSA

Personalised recommendations