Abstract
Neurons are continuously subjected to fluctuating levels of oxidative stress, neurotransmitters and other compounds that have the potential of damaging the cells. Under physiological conditions the levels of these compounds do not reach pathological levels and the cells survive. Under pathological conditions, however, the compounds reach toxic levels and apoptotic cell death can be triggered. Endogeneous neuroprotective factors are molecules which can prevent the switch from survival to cell death. These factors work in several ways, only a few of which will be considered in this chapter.
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Barnstable, C.J., Tombran-Tink, J. (2006). Molecular Mechanisms of Neuroprotection in the Eye. In: Hollyfield, J.G., Anderson, R.E., LaVail, M.M. (eds) Retinal Degenerative Diseases. Advances in Experimental Medicine and Biology, vol 572. Springer, Boston, MA. https://doi.org/10.1007/0-387-32442-9_40
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DOI: https://doi.org/10.1007/0-387-32442-9_40
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