Morphological Changes in the Rat Carotid Body in Acclimatization and Deacclimatization to Hypoxia

Conference paper


The carotid bodies are enlarged in the rats exposed to long term hypoxia. In some studies the animals were exposed to hypoxia for relatively short periods, and in other studies for relatively long periods. However, most authors use the term “chronic hypoxia” in their publications. This terminology can cause much confusion. On the other hand, there are no morphological studies of the carotid bodies after the termination of chronic hypoxia except in a few instances (Heath et al., 1973). Recently high altitude training has been used to try to improve some physical conditions. High altitude exercise can help to make clear morphological changes in chemoreceptor organs during acclimatization to hypoxia and during deacclimatization after chronic hypoxia is terminated.


Vasoactive Intestinal Polypeptide Carotid Body Chronic Hypoxia Hypoxic Exposure Immunoreactive Fiber 
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Copyright information

© Springer 2006

Authors and Affiliations

    • 1
    • 2
    • 3
    • 4
    • 5
  1. 1.Department of OtorhinolaryngologyYokohama City University School of MedicineYokohama
  2. 2.Department of PhysiologyNational Defense Medical CollegeTokorozawa
  3. 3.Department of MedicineLabour Welfare Corporation Ehime Rosai HospitalEhime
  4. 4.International Buddhist UniversityOsaka
  5. 5.Laboratory for Anatomy and Physiology, Department of Sport and Medical ScienceKokushikan UniversityTokyoJapan

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