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An Overview on the Homeostasis of Ca2+ in Chemoreceptor Cells of the Rabbit and Rat Carotid Bodies

  • S.V. CONDE
  • A.I. CACERES
  • I. VICARIO
  • A. ROCHER
  • A. OBESO
  • C. GONZALEZ
Part of the ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY book series (AEMB, volume 580)

Abstract

Carotid body (CB) chemoreceptors sense arterial PO2 and PCO2/pH becoming activated in hypoxic hypoxia and in all types of acidosis. The sensing structures in the CB are chemoreceptor cells (CBCC), which are connected synaptically with the sensory nerve endings of the carotid sinus nerve (CSN). In situations of hypoxia and acidosis, CBCC are activated and their rate of release of neurotransmitters (NT) increase, promoting an increase in the activity of the CSN and subsequent ventilatory and cardiovascular reflexes (5).

Keywords

Carotid Body Phenyl Acetic Acid Cyclopiazonic Acid Sensory Nerve Ending Carotid Sinus Nerve 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 2006

Authors and Affiliations

  • S.V. CONDE
    • 1
  • A.I. CACERES
    • 1
  • I. VICARIO
    • 1
  • A. ROCHER
    • 1
  • A. OBESO
    • 1
  • C. GONZALEZ
    • 1
  1. 1.Departamento de Bioquimíca y Biología Molecular y Fisiología/IBGMFacultad de Medicina. Universidad de Valladolid/CSIC.Valladolid.Spain

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