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Split-Liver Transplantation

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Liver and Pancreatic Diseases Management

Part of the book series: Advances in Experimental Medicine and Biology ((volume 574))

3. Conclusion

Over the last 15 years, split-liver transplantation has become a technique applied by many transplant centers around the world. So far, it is predominantly used for transplanting one child and one adult with the two parts of one donor liver. Although slightly different techniques are used by different centers, the extended right/left-lateral splitting is rather standardized and is performed either ex-situ or in-situ. While the in-situ approach appears to be superior in medical terms, the ex-situ technique has logistical advantages so that the decision must be made in dependence of each individual setting. Splitting of a donor liver for two adults is still an experimental procedure and limited to selected centers.

In summary, split-liver transplantation is a technically demanding procedure, but well performed, it can lead to good results. In conjunction with living donor liver transplantation as well as the use of marginal donor organs from deceased donors, it offers the chance to extend the number of available donor organs and, thereby, to reduce the mortality on the waiting lists for liver transplantation.

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Schlitt, H.J., Ross, M., Obed, A. (2006). Split-Liver Transplantation. In: Habib, N.A., Canelo, R. (eds) Liver and Pancreatic Diseases Management. Advances in Experimental Medicine and Biology, vol 574. Springer, Boston, MA . https://doi.org/10.1007/0-387-29512-7_3

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