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Comparative Analysis of Electrostatic Patterns for Promoter and Nonpromoter DNA in E. Coli Genome

  • S. G. KamzolovaEmail author
  • A. A. Sorokin
  • P. M. Beskaravainy
  • A. A. Osypov
Chapter

Abstract

Distribution of electrostatic potential of the complete sequence of E. coli genome was calculated. It is found that DNA is not a uniformly charged molecule. There are some local inhomogeneities in its electrostatic profile, which correlate with promoter sequences. Electrostatic patterns of promoter DNAs can be specified due to the presence of some distinctive motifs that may be involved as promoter signal elements in RNA-polymerase-promoter recognition.

Key words

E. coli genome promoters coding region electrostatic potential distribution 

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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • S. G. Kamzolova
    • 1
    Email author
  • A. A. Sorokin
    • 1
  • P. M. Beskaravainy
    • 1
  • A. A. Osypov
    • 1
  1. 1.Institute of Cell BiophysicsRussian Academy of SciencesPushchino, Moscow oblastRussia

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