Abstract
Distribution of electrostatic potential of the complete sequence of E. coli genome was calculated. It is found that DNA is not a uniformly charged molecule. There are some local inhomogeneities in its electrostatic profile, which correlate with promoter sequences. Electrostatic patterns of promoter DNAs can be specified due to the presence of some distinctive motifs that may be involved as promoter signal elements in RNA-polymerase-promoter recognition.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer Science+Business Media, Inc.
About this chapter
Cite this chapter
Kamzolova, S.G., Sorokin, A.A., Beskaravainy, P.M., Osypov, A.A. (2006). Comparative Analysis of Electrostatic Patterns for Promoter and Nonpromoter DNA in E. Coli Genome. In: Kolchanov, N., Hofestaedt, R., Milanesi, L. (eds) Bioinformatics of Genome Regulation and Structure II. Springer, Boston, MA. https://doi.org/10.1007/0-387-29455-4_7
Download citation
DOI: https://doi.org/10.1007/0-387-29455-4_7
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-29450-6
Online ISBN: 978-0-387-29455-1
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)