Abstract
Prediction and reconstruction of metabolic pathways from rudimentary molecular data is a fundamental way to understand the logic of life. Comparing metabolic pathways are important to identify conservation and variations among different biology systems. Alignment is a strong indicator of the biologically significant relationship. In this article, a definition of metabolic pathway is presented. An alignment algorithm and a computational system are developed to reveal the similarities between metabolic pathways. A web-based program for prediction and alignment of metabolic pathway, PathAligner, is available at http://bibiserv.techfak.uni-bielefeld.de/pathaligner.
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© 2006 Springer Science+Business Media, Inc.
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Chen, M., Hofestaedt, R. (2006). Prediction and Alignment of Metabolic Pathways. In: Kolchanov, N., Hofestaedt, R., Milanesi, L. (eds) Bioinformatics of Genome Regulation and Structure II. Springer, Boston, MA. https://doi.org/10.1007/0-387-29455-4_34
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DOI: https://doi.org/10.1007/0-387-29455-4_34
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-29450-6
Online ISBN: 978-0-387-29455-1
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