Prediction and Alignment of Metabolic Pathways

  • M. Chen
  • R. HofestaedtEmail author


Prediction and reconstruction of metabolic pathways from rudimentary molecular data is a fundamental way to understand the logic of life. Comparing metabolic pathways are important to identify conservation and variations among different biology systems. Alignment is a strong indicator of the biologically significant relationship. In this article, a definition of metabolic pathway is presented. An alignment algorithm and a computational system are developed to reveal the similarities between metabolic pathways. A web-based program for prediction and alignment of metabolic pathway, PathAligner, is available at

Key words

Metabolic pathways prediction alignment pathAligner 


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  1. 1.Bioinformatics/Medical Informatics, Faculty of TechnologyBielefeld UniversityBielefeldGermany
  2. 2.College of Life ScienceZhejiang UniversityHangzhouChina

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