Universal Seven-Cluster Structure of Genome Fragment Distribution: Basic Symmetry in Triplet Frequencies
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We found a universal seven-cluster structure in bacterial genomic sequences and explained its properties. Based on the analysis of 143 completely sequenced bacterial genomes available in GenBank in August 2004, we show that there are four ‘pure’ types of the seven-cluster structure observed. The type of cluster structure depends on GC content and reflects basic symmetry in triplet frequencies. Animated 3D-scatters of bacterial genomes seven-cluster structure are available on our web site: http://www.ihes.fr/~zinovyev/7clusters.
Key wordstriplet frequencies genome fragments codons mean-field approximation symmetry visualization
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