Comparative Genomics and Evolution of Bacterial Regulatory Systems
- 773 Downloads
Recent advances in genome sequencing and development of comparative genomics techniques allow one to study evolution of regulation in prokaryotes at several different levels: microevolution of orthologous regulatory sites, changes in regulon content, evolution of interacting regulatory systems, and co-evolution of transcription factors and their binding signals. Regulatory interactions appear to be very dynamic in some cases and surprisingly stable in others. The review presents several examples where comparative analysis uncovered plausible scenarios of evolution of regulatory systems.
Key wordsregulation evolution transcription binding site riboswitch
Unable to display preview. Download preview PDF.