Skip to main content
SpringerLink
Log in

Ablation of Liver Metastases

  • Chapter
Tumor Ablation

Abstract

Metastatic liver disease represents one of the most common clinical problems in oncology practice. Multiple treatment options are available including hepatic resection, chemoembolization, intraarterial and systemic chemotherapy, cryotherapy, and radiofrequency ablation (RFA) (1,2).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bhattacharya R, Rao S, Kowdley KV. Liver involvement in patients with solid tumors of nonhepatic origin. Clin Liver Dis 2002;6:1033–1043.

    Article  PubMed  Google Scholar 

  2. Nordlinger B, Rougier P. Nonsurgical methods for liver metastases including cryotherapy, radiofrequency ablation and infusional treatment: what’s new in 2001? Curr Opin Oncol 2002;14:420–423.

    Article  PubMed  Google Scholar 

  3. Sica GT, Ji H, Ros PR. CT and MR imaging of hepatic metastases. AJR 2000;174:691–698.

    Article  PubMed  CAS  Google Scholar 

  4. Vails C, Andia E, Sanchez A, et al. Hepatic metastases from colorectal cancer: preoperative detection and assessment of resectability with helical CT. Radiology 2001;218:55–60.

    Article  Google Scholar 

  5. Harvey CJ, Blomley MJK, Eckersley RJ, et al. Hepatic malignancies: improved detection with pulse-inversion US in the late phase of enhancement with SHU 508A—early experience. Radi ology 2000;216:903–908.

    Article  CAS  Google Scholar 

  6. Albrecht T, Hoffmann CW, Schmitz SA, et al. Phase-inversion sonography during the liver specific late phase of contrast enhancement: improved detection of liver metastases. AJR 2001;176:1191–1198.

    Article  PubMed  CAS  Google Scholar 

  7. Quaia E, Bertolotto M, Forgacs B, et al. Detection of liver metastases by pulse inversion harmonic imaging during Levovist late phase: comparison with conventional ultrasound and helical CT in 160 patients. Eur Radiol 2003;13:475–483.

    PubMed  Google Scholar 

  8. Solbiati L, Tonolini M, Cova L, et al. The role of contrast-enhanced ultrasound in the detection of focal liver lesions. Eur Radiol 2001;11:E15–E26.

    Article  PubMed  Google Scholar 

  9. Albrecht T, Blomley MJ, Burns PN, et al. Improved detection of hepatic metastases with pulse-inversion US during the liver-specific phase of SHU 508A: multicenter study. Radiology 2003;227:361–370.

    Article  PubMed  Google Scholar 

  10. Semelka RC, Helmberger TC. Contrast agents for MR imaging of the liver. Radiology 2001;218:27–38.

    Article  PubMed  CAS  Google Scholar 

  11. Geoghegan JG, Scheele J. Treatment of colorectal liver metastases. Br J Surg 1999;86:158–169.

    Article  PubMed  CAS  Google Scholar 

  12. Yoon SS, Tanabe KK. Surgical treatment and other regional treatments for colorectal cancer liver metastases. Oncologist 1999;4:197–208.

    PubMed  CAS  Google Scholar 

  13. Taylor M, Forster J, Langer B, et al. A study of prognostic factors for hepatic resection for colorectal metastases. Am J Surg 1997;173:467–471.

    Article  PubMed  CAS  Google Scholar 

  14. Nordlinger B, Guigner M, Vaillant JC, et al. Surgical resection of colorectal carcinoma metastases to the liver. A prognostic scoring system to improve case selection based on 1568 patients, Association Francaise de Chirurgie. Cancer 1996;77:1254–1262.

    Article  PubMed  CAS  Google Scholar 

  15. Elias D, Cavalcanti A, Sabourin JC, et al. Resection of liver metastases from colorectal cancer: the real impact of the surgical margin. Eur J Surg Oncol 1998;24:174–179.

    Article  PubMed  CAS  Google Scholar 

  16. Cady B, Jenkins RL, Steelde GD, et al. Surgical margin in hepatic resection for colorectal metastasis: a critical and improvable determinant of outcome. Am Surg 1998;227:566–571.

    CAS  Google Scholar 

  17. Holm A, Bradley E, Aldrete JS. Hepatic resection of metastases from colorectal carcinoma. Morbidity, mortality and patterns of recurrence. Ann Surg 1989;209:428–434.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  18. Fong Y, Salo J. Surgical therapy of hepatic colorectal metastasis. Semin Oncol 1999;26:514–523.

    PubMed  CAS  Google Scholar 

  19. Liu LX, Zhang WH, Jiang HC. Current treatment for liver metastases from colorectal cancer. World J Gastroenterol 2003;9:193–200.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Hugh TJ, Kinsella AR, Poston GJ. Management strategies for colorectal liver metastases—part I. Surg Oncol 1997;6:19–30.

    Article  PubMed  CAS  Google Scholar 

  21. Elias D, Lasser PH, Montrucolli D, Bonvallo S, Spielmann M. Hepatectomy for liver metastases from breast cancer. Eur J Surg Oncol 1995;21:510–513.

    Article  PubMed  CAS  Google Scholar 

  22. Elias D, Cavalcanti A, Eggenspieler P, et al. Resection of liver metastases from a noncolorectal primary: indications and results based on 147 monocentric patients. J Am Coll Surg 1998;187:487–493.

    Article  PubMed  CAS  Google Scholar 

  23. Raab R, Nussbaum KT, Behrend M, et al. Liver metastases of breast cancer: results of liver resection. Anticancer Res 1998;18:2231–2234.

    PubMed  CAS  Google Scholar 

  24. Maksan SM, Lehnert T, Bastert G, et al. Curative liver resection for metastatic breast cancer. Eur J Surg Oncol 2000;26:209–212.

    Article  PubMed  CAS  Google Scholar 

  25. Chen H, Hardacre JM, Uzar A, et al. Isolated liver metastases from neuroendocrine tumors: does resection prolong survival? J Am Coll Surg 1998;187:88–93.

    Article  PubMed  CAS  Google Scholar 

  26. Berney T, Mentha G, Roth AD, et al. Results of surgical resection of liver metastases from non-colorectal primaries. Br J Surg 1998;85:1423–1427.

    Article  PubMed  CAS  Google Scholar 

  27. Lindell G, Ohlsson B, Saarela A, et al. Liver resection of noncolorectal secondaries. J Surg Oncol 1998;69:66–70.

    Article  PubMed  CAS  Google Scholar 

  28. Maksan SM, Lehnert T, Bastert G, Herfarth C. Curative liver resection for metastatic breast cancer. Eur J Oncol 2000;26:209–212.

    Article  CAS  Google Scholar 

  29. Hellman P, Ladjevardi S, Skogseid B, et al. Radiofrequency tissue ablation using cool tip for liver metastases of neuroendocrine tumors. World J Surg 2002;26:1052–1056.

    Article  PubMed  Google Scholar 

  30. Livraghi T, Goldberg SN, Solbiati L, et al. Percutaneous radiofrequency ablation of liver metastases from breast cancer: initial experience in 24 patients. Radiology 2001;220:145–149.

    Article  PubMed  CAS  Google Scholar 

  31. Goldberg SN, Gazelle GS, Mueller PR. Thermal ablation therapy for focal malignancy. A unified approach to underlying principles, techniques, and diagnostic imaging guidance. AJR 2000;174:323–331.

    Article  PubMed  CAS  Google Scholar 

  32. Solbiati L, Goldberg SN, Ierace T, et al. Hepatic metastases: percutaneous radio-frequency ablation with cooled-tip electrodes. Radiology 1997;205:367–373.

    Article  PubMed  CAS  Google Scholar 

  33. Solbiati L, Ierace T, Goldberg SN, et al. Percutaneous US-guided radiofrequency tissue ablation of liver metastases: treatment and follow-up in 16 patients. Radiology 1997;202:195–203.

    Article  PubMed  CAS  Google Scholar 

  34. Livraghi T, Goldberg SN, Lazzaroni S, et al. Small hepatocellular carcinoma: treatment with radiofrequency ablation versus ethanol injection. Radiology 1999;210:655–661.

    Article  PubMed  CAS  Google Scholar 

  35. Livraghi T, Goldberg SN, Lazzaroni S, et al. Hepatocellular carcinoma: radio-frequency ablation of medium and large lesions. Radiology 2000;214:761–768.

    Article  PubMed  CAS  Google Scholar 

  36. Solbiati L, Livraghi T, Goldberg SN, et al. Percutaneous radiofrequency ablation of hepatic metastases from colorectal cancer: long-term results in 117 patients. Radiology 2001;221:159–166.

    Article  PubMed  CAS  Google Scholar 

  37. Curley SA, Izzo F, Delrio P, et al. Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies: results in 123 patients. Ann Surg 1999;230:1–8.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  38. Jiao LR, Hansen PD, Havlik R, et al. Clinical short-term results of radiofrequency ablation in primary and secondary liver tumors. Am J Surg 1999;177:303–306.

    Article  PubMed  CAS  Google Scholar 

  39. Lencioni R, Goletti O, Armillotta N, et al. Radiofrequency thermal ablation of liver metastasis with cooled-tip electrode needle: results of a pilot clinical trial. Eur Radiol 1998;8:1205–1211.

    Article  PubMed  CAS  Google Scholar 

  40. Rose DM, Allegra DP, Bostick PJ, et al. Radiofrequency ablation: a novel primary and adjunctive ablative technique for hepatic malignancies. Am Surg 1999;65:1009–1014.

    PubMed  CAS  Google Scholar 

  41. Rossi S, Buscarini E, Garbagnati F, et al. Percutaneous treatment of small hepatic tumors by an expandable RF needle electrode. AJR 1998;170:1015–1022.

    Article  PubMed  CAS  Google Scholar 

  42. De Baere T, Elias D, Dromain C, et al. Radiofre-quency ablation of 100 hepatic metastases with a mean follow-up of more than 1 year. AJR 2000;175(6):1619–1625.

    Article  PubMed  Google Scholar 

  43. Goldberg SN, Gazelle GS, Solbiati L, et al. Radiofrequency tissue ablation: increased lesion diameter with a perfusion electrode. Acad Radiol 1996;3:636–644.

    Article  PubMed  CAS  Google Scholar 

  44. Goldberg SN, Solbiati L, Hahn PF, et al. Large-volume tissue ablation with radiofrequency by using a clustered, internally cooled electrode technique: laboratory and clinical experience in liver metastases. Radiology 1998;209:371–379.

    Article  PubMed  CAS  Google Scholar 

  45. Goldberg SN, Stein MC, Gazelle GS, et al. Percutaneous radiofrequency tissue ablation: optimization of pulsed-radiofrequency technique to increase coagulation necrosis. J Vase Interv Radiol 1999;10:907–916.

    Article  CAS  Google Scholar 

  46. Livraghi T, Goldberg SN, Monti F, et al. Saline-enhanced radiofrequency tissue ablation in the treatment of liver metastases. Radiology 1997;202:205–210.

    Article  PubMed  CAS  Google Scholar 

  47. De Baere T, Bessoud B, Dromain C, et al. Percutaneous radiofrequency ablation of hepatic tumors during temporary venous occlusion. AJR 2002;178:53–59.

    Article  PubMed  Google Scholar 

  48. Rhim H, Goldberg SN, Dodd GD III, et al. Essential techniques for successful radio-frequency thermal ablation of malignant hepatic tumors. Radiographics 2001;21(spec. no.):S 17–35.

    Article  Google Scholar 

  49. Goldberg SN, Kamel IR, Kruskal JB, et al. Radio-frequency ablation of hepatic tumors: increased tumor destruction with adjuvant liposomal doxorubicin therapy. AJR 2002;179:93–101.

    Article  PubMed  Google Scholar 

  50. Akhurst T, Larson SM. Positron emission tomography imaging of colorectal cancer. Semin Oncol 1999:26(5):577–583.

    PubMed  CAS  Google Scholar 

  51. Anderson GS, Brinkmann F, Soulen MC, et al. FDG positron emission tomography in the surveillance of hepatic tumors treated with radio-frequency ablation. Clin Nucl Med 2003;28:192–197.

    PubMed  Google Scholar 

  52. Elias D, De Baere T, Smayra T, et al. Percutaneous radiofrequency thermoablation as an alternative to surgery for treatment of liver tumour recurrence after hepatectomy. Br J Surg 2002;89:752–756.

    Article  PubMed  CAS  Google Scholar 

  53. Livraghi T, Solbiati L, Meloni F, et al. Percutaneous radiofrequency ablation of liver metastases in potential candidates for resection: the “test of time” approach. Cancer 2003;97:3027–3035.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Ospedale Civile Busto Arsizio, Busto Arsizio, Italy, Italy

    Luigi Solbiati MD (Chairman), Tiziana Ierace MD, Massimo Tonolini MD & Luca Cova MD

Authors
  1. Luigi Solbiati MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tiziana Ierace MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Massimo Tonolini MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Luca Cova MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02115, USA

    Eric vanSonnenberg MD (Chief of Radiology, Interventional Radiologist) (Chief of Radiology, Interventional Radiologist)

  2. Brigham and Women’s Hospital Children’s Hospital, Boston, MA, 02115, USA

    Eric vanSonnenberg MD (Chief of Radiology, Interventional Radiologist) (Chief of Radiology, Interventional Radiologist)

  3. Boston, MA, 02115, USA

    William N. McMullen (Interventional Oncology Consultant) (Interventional Oncology Consultant)

  4. Department of Radiology, Ospedale Civile Busto Arsizio, 21052, Busto Arsizio, Italy

    Luigi Solbiati MD (Chairman) (Chairman)

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer Science+Business Media, Inc.

About this chapter

Cite this chapter

Solbiati, L., Ierace, T., Tonolini, M., Cova, L. (2005). Ablation of Liver Metastases. In: vanSonnenberg, E., McMullen, W.N., Solbiati, L., Livraghi, T., Müeller, P.R., Silverman, S.G. (eds) Tumor Ablation. Springer, New York, NY. https://doi.org/10.1007/0-387-28674-8_25

Download citation

  • DOI: https://doi.org/10.1007/0-387-28674-8_25

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-95539-1

  • Online ISBN: 978-0-387-28674-7

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation