Interaction of Arousal States with Depression of Acute Hypoxic Ventilatory Response by 0.1 MAC Halothane

  • Jaideep J. Pandit
  • Ben Moreau
  • Peter A. Robbins
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 551)


It is well-established that volatile anesthetic agents at doses of < 0.2 MAC depress the acute hypoxic ventilatory response (AHVR) by ∼50–70%1,2. However, the effect of anesthetic agents can be very variable3,4.


Ventilatory Response Arousal State Visual Analog Pain Score Hypoxic Ventilatory Response Volatile Anesthetic Agent 
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Copyright information

© Kluwer Academic/Plenum Publishers, New York 2004

Authors and Affiliations

  • Jaideep J. Pandit
    • 1
  • Ben Moreau
    • 2
  • Peter A. Robbins
    • 2
  1. 1.Nuffield Department of AnaestheticsJohn Radcliffe HospitalOxfordUK
  2. 2.University Laboratory of PhysiologyOxfordUK

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