A Physical Model of Inspiratory Flow Limitation in Awake Healthy Subjects

  • Abdelkebir Sabil
  • André Eberhard
  • Pierre Baconnier
  • Gila Benchetrit
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 551)


The obstructive syndrome of sleep apnea/hypopnea is characterized by repeated partial or total obstructions of the upper airways (UA) [1] resulting in intermittent asphyxia and repeated micro-arousals. Sleep disordered breathing affects about 9% of males and 4.5% of females between the ages of 30 and 60 years [2], 15% to 20% of elderly people [3] and 5% to 10% of children [4]. Sleep apnea and hypopnea events are easily identified while more subtle events, such as inspiratory flow limitation episodes, are difficult to detect. Flow limitation is the result of a partial occlusion of the upper airway during sleep.


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Copyright information

© Kluwer Academic/Plenum Publishers, New York 2004

Authors and Affiliations

  • Abdelkebir Sabil
    • 1
  • André Eberhard
    • 1
  • Pierre Baconnier
    • 1
  • Gila Benchetrit
    • 1
  1. 1.Laboratoire TIMC/IMAG (UMR CNRS 5525)Université Joseph Fourier (UJF), Faculté de Médecine de GrenobleLa Tranche CedexFrance

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