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Modulation of Inspiratory Inhibition of the Bötzinger Complex by Raphe Pallidus and Locus Coeruleus in Rabbits

  • Guimin Wang
  • Shuyan Yu
  • Fayan Zhang
  • Yanchun Li
  • Ying Cao
  • Qin Li
  • Gang Song
  • Heng Zhang
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 551)

Abstract

In mammals, the respiratory rhythm is generated by the brainstem neuronal network. The Bötzinger complex (Böt.C) is a group of inhibitory expiratory neurons at the rostral end of the ventral respiratory group (VRG) near the retrofacial nucleus. Neurons in the Böt.C have widespread inhibitory connections with other medullary respiratory neurons and phrenic motoneurons.1,2 Long train stimulation of the Böt.C caused inhibition of inspiration and inspiratory to expiratory phase-switching.3,4

Keywords

GABAa Receptor Locus Coeruleus Respiratory Rhythm Ventral Respiratory Group Phrenic Motoneuron 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic/Plenum Publishers, New York 2004

Authors and Affiliations

  • Guimin Wang
    • 1
  • Shuyan Yu
    • 1
  • Fayan Zhang
    • 1
  • Yanchun Li
    • 1
  • Ying Cao
    • 1
  • Qin Li
    • 1
  • Gang Song
    • 1
  • Heng Zhang
    • 1
  1. 1.Institute of Physiology, School of MedicineShandong UniversityJinanP.R. China

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