Preview
Unable to display preview. Download preview PDF.
References
Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301–1308
Rubenfeld GD (2003) Epidemiology of acute lung injury. Crit Care Med 31:S276–S284
Pinhu L Whitehead T, Evans T, Griffths M (2003) Ventilator-associated lung injury. Lancet. 361:332–340
Dreyfuss D, Saumon G (1998) Ventilator-induced lung injury. Lessons from experimental studies. Am J Respir Crit Care Med. 157:294–323
Amato MBP, Barbas CSV, Medeiros DM, et al (1998) Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 338:347–354
Putensen C, Baum M, Hormann C (1993) Selecting ventilator settings according to variables derived from the quasi-static pressure/volume relationship in patients with acute lung injury. Anesth Analg 77:436–447
Harris RS, Hess DR, Venegas JG (2000) An objective analysis of the pressure-volume curve in the acute respiratory distress syndrome. Am J Respir Crit Care Med 161:432–439
Victorino JA, Borges JB, Okamato, et al (2004) Imbalances in regional lung ventilation. A validation study on electrical impedance tomography. Am J Respir Crit Care Med 169:791–800
Slutsky AS (1999) Lung injury caused by mechanical ventilation. Chest 116(Suppl): 9S–15S
Tangelo E (1972) Local alveolar size and Tran pulmonary pressure in situ and in isolated lungs. Respir Physiology 14:251–266
Daly BDT, Parks GE, Edmonds CH, Hibbs CW, Norman JC (1975) Dynamic alveolar mechanics as studied by videomicroscopy. Respir Physiol 24:217–232
Dunnill MS (1967) Effect of lung inflation on alveolar surface area in the dog. Nature 214:1013–1014
Flicker E, Lee JS (1974) Equilibrium of force of subpleural alveoli: implications to lung mechanics. J Appl Physiol 36:366–374
Forrest JB (1970) The effect of changes in lung volume on the size and shape of alveoli. J Physiol 210:533–547
Klingele TG, Staub NC (1970) Alveolar shape changes with volume in isolated, air-filled lobes of cat lung. J Appl Physiol 28:411–414
Kuno K, Staub NC (1968) Acute mechanical effects of lung volume changes on artificial microholes in alveolar walls. J Appl Physiol 24:83–92
Storey WF, Staub NC (1962) Ventilation of terminal air units. J Appl Physiol 17:391–397
Gil J, Weibei ER (1972) Morphological study of pressure-volume hysteresis in rat lungs fixed by vascular perfusion. Respir Physiol 15:190–213
Gil J, Bachofen H, Gehr P, Weibel ER (1979) Alveolar volume-surface area relation in air and saline-filled lungs fixed by vascular perfusion. J Appl Physiol Respir Environ Exercise Physiol 47:990–1001
Bachofen H, Gehr P, Weibel ER (1979) Alterations of mechanical properties and morphology in excised rabbit lung rinsed with detergent. J Appl Physiol Respir Environ Exercise Physiol 47:1002–1010
Forest JB (1976) Lung tissue plasticity: Morphometric analysis of anisotropic strain in liquid filled lungs. Respir Physiol 27:223–239
Carney DE, Bredenberg CE, Schiller HJ, et al (1999) The mechanism of lung volume change during mechanical ventilation. Am J Respir Crit Care Med 160:1697–1702
Smaldone GC, Mitzner W, Itoh H (1983) Role of alveolar recruitment in lung inflation: influence on pressure-volume hysteresis. J Appl Physiol Respir Environ Exercise Physiol 55:1321–1332
Lum H, Huang I, Mitzner W (1990) Morphological evidence for alveolar recruitment during inflation at high transpulmonary pressure. J Appl Physiol 68:2280–2286
Mercer RR, Laco JM, Crapo JD (1987) Three-dimensional reconstruction of alveoli in the rat lung for pressure-volume relationships. J Appl Physiol 62:1480–1487
Salmon RB, Primiano FP, Saidel GM, Niewoehner DE (1981) Human lung pressure-volume relationships: alveolar collapse and airway closures. J Appl Physiol Respir Environ Exercise Physiol 51:353–362
Moreci AP, Norman JC (1973) Measurements of alveolar sac diameters by incident-light photomicrography. Ann Thorac Surg 15:179–185
Boyle J, Englestein ES, Sinoway LI (1977) Mean air space diameter, lung surface area and alveolar surface tension. Respiration 34:241–249
Sera T, Fujioka H, Yokota H, et al (2004) Localized compliance of small airways in excised rat lungs using microfocal X-ray tomography. J Appl Physiol 96:1665–1673
Soutiere SE, Mitzner W (2004) On defining total lung capacity in the mouse. J Appl Physiol 96:1658–1664
Soutiere SE, Tankersley CG, Mitzner W (2004) Differences in alveolar size inbred mouse strains. Respir Physiol Neurobiol 140:283–291
Escolar JD, Escolar MA, Guzman J, Roques M (2002) Pressure volume curve and alveolar recruitment/derecruitment. A morphometric model of the respiratory cycle. Histol Histophatol 17:383–392
Yager D, Feldman H, Fung YC (1992) Microscopic vs macroscopic deformation of pulmonary alveolar duct. J Appl Physiol 72:1348–1354
Tschumperlin DJ, Margulies SS (1999) Alveolar epithelial surface area-volume relationship in isolated rat lungs. J Appl Physiol 86:2026–2033
Hickling KG (1998) The pressure-volume curve is greatly modified by recruitment. A mathematical model of ARDS lungs. Am J Respir Crit Care Med 158:194–202
Hickling KG (2001) Best compliance during a detrimental, but not incremental, positive end-expiratory pressure trial is related to open-lung positive end-expiratory pressure. A mathematical model of acute respiratory distress syndrome lungs. Am J Respir Crit Care Med 163:69–78
Pelosi P, Goldner M, McKibben A, et al (2001) Recruitment and derecruitment during acute respiratory failure. An experimental study. Am J Respir Crit Care Med 164:122–130
Crotti S, Mascheroni D, Caironi P, et al (2001) Recruitment and derecruitment during acute respiratory failure. A clinical study. Am J Respir Crit Care Med 164:131–140
Oldmixon EH, Hoppin FG (1991) Alveolar septal folding and lung inflation history. J Appl Physiol 71:2369–2379
Gatto LA, Fluck RR, Nieman GF (2004) Alveolar mechanics in the acutely injured lung: Role of alveolar instability in the pathogenesis of ventilator-induced lung injury. Respir Care 49:1045–1055
Mead J, Takishima T, Leith D (1970) Stress distribution in lungs: a model of pulmonary elasticity. J Appl Physiol 28:596–608
West JB (2000) Respiratory Physiology — The Essentials, 6th ed Lippincott Williams & Wilkins, Philadelphia, p 83
Neumann P, Berglund JE, Mondejar EF, Magnusson A, Hedenstierna G (1998) Dynamics of lung collapse and recruitment during prolonged breathing in porcine lung injury. J Appl Physiol 85:1522–1543
Grasso S, Terragni P, Mascia L, et al (2004) Airway pressure-time curve profile (stress index) detects tidal recruitment/hyperinflation in experimental acute lung injury. Crit Care Med 32:1018–1027
Halter JM, Steinberg JM, Schiller HJ, et al (2003) Positive end-expiratory pressure (PEEP) after a recruitment maneuver prevents both alveolar collapse and recruitment/derecruitment. Am J Respir Crit Care Med 167:1620–1626
Steinberg J, Schiller HJ, Halter JM, et al (2004) Alveolar instability causes early ventilator-induced lung injury independent of neutrophils. Am J Respir Crit Care Med 169:57–63
Tremblay L, Valenza F, Riberio SP, Li J, Slutsky AS (1997) Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 99:944–952
Hotchkiss JR, Simonson DA, Marek DJ, Marini JJ, Dries DJ (2002) Pulmonary microvascular fracture in a patient with acute respiratory distress syndrome. Crit Care Med 30:2368–2370
Gajic O, Lee J, Doerr CH, Berrios JC, Myers JL, Hubmayr RD (2003) Ventilator-induced cell wounding and repair in the intact lung. Am J Respir Crit Care Med 167:1057–1063
Dreyfuss DP, Soler P, Basset G, Saumon G (1988) High inflation pressure pulmonary edema: respective effects of high airway pressure, high tidal volume an positive end-expiratory pressure. Am Rev Respir Dis 137:1159–1164
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
DiRocco, J., Carney, D., Nieman, G. (2005). The Mechanism of Ventilator-induced Lung Injury: Role of Dynamic Alveolar Mechanics. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2005. EN]Yearbook of Intensive Care and Emergency Medicine, vol 2005. Springer, New York, NY. https://doi.org/10.1007/0-387-26272-5_9
Download citation
DOI: https://doi.org/10.1007/0-387-26272-5_9
Publisher Name: Springer, New York, NY
Print ISBN: 978-3-540-23476-0
Online ISBN: 978-0-387-26272-7
eBook Packages: MedicineMedicine (R0)