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Yearbook of Intensive Care and Emergency Medicine 2005 pp 103–115Cite as

Modulators of Ventilator-induced Lung Injury

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Part of the book series: EN]Yearbook of Intensive Care and Emergency Medicine ((volume 2005))

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References

  1. Brower RG, Matthay M, Schoenfeld D (2002) Meta-analysis of acute lung injury and acute respiratory distress syndrome trials. Am J Respir Crit Care Med 166:1515–1517

    PubMed  Google Scholar 

  2. The ARDS network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301–1308

    Google Scholar 

  3. Amato MB, Barbas CS, Medeiros DM, et al (1998) Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 338:347–354

    Article  PubMed  Google Scholar 

  4. Ricard JD, Dreyfuss D, Saumon G (2003) Ventilator-induced lung injury. Eur Respir J 22:2s–9s

    Article  Google Scholar 

  5. Ricard JD, Dreyfuss D (2001) Cytokines during ventilator-induced lung injury: a word ofd caution. Anesth Analg 93:251–252

    Article  PubMed  Google Scholar 

  6. Marttynowicz MA, Minor TA, Walters BJ, Hubmayr RD (1999) Regional expansion of oleic acid-injured lungs. Am J Respir Crit Care Med 160:250–258

    PubMed  Google Scholar 

  7. Ranieri VM, Suter AS, Tortorella C, et al (1999) Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial. JAMA 282:54–61

    Article  PubMed  Google Scholar 

  8. Pugin J (2003) Molecular mechanisms of lung cell activation induced by cyclic stretch. Crit Care Med 31:S200–S206

    Article  PubMed  Google Scholar 

  9. Nunn JF (1993) Distribution of pulmonary ventilation and perfusion. In: Nunn JF (ed) Nunn's Applied Respiratory Physiology, 4th Ed. Butterworth-Heinemann, Oxford, pp 156–197

    Google Scholar 

  10. Pelosi P, Tubiolo D, Mascheroni D, et al (1998) Effects of the prone position on respiratory mechanics and gas exchange during acute lung injury. Am J Respir Crit. Care Med 157:387–393

    PubMed  Google Scholar 

  11. Gattinoni L, Pelosi P, Crotti S, Valenza F (1995) Effects of positive end-expiratory pressure on regional distribution of tidal volume and recruitment in adult respiratory distress syndrome. Am J Respir Crit Care Med 151:1807–1814

    PubMed  Google Scholar 

  12. Marini JJ, Culver BH, Butler J (1981) Mechanical effect of lung distention with positive pressure on ventricular function. Am Rev Respir Dis 124:382–386

    PubMed  Google Scholar 

  13. Broccard A, Shapiro R, Schmitz L, Adams AB, Nahum A, Marini J (2000) Prone positioning attenuates and redistributes ventilator-induced lung injury in dogs. Crit Care Med 28:295–303

    Article  PubMed  Google Scholar 

  14. Johansson MJ, Wiklund A, Flatebo T, Nicolaysen A, Nicolaysen G, Walther SM (2004) PEEP affects regional redistribution of ventilation differently in prone and supine sheep. Crit Care Med 32:2039–2044

    Article  PubMed  Google Scholar 

  15. Gattinoni L, Tognoni G, Pesenti A, et al (2001) Effect of prone positioning on the survival of patients with acute respiratory failure. N Engl J Med 345:568–573

    Article  PubMed  Google Scholar 

  16. Mancebo J, Rialp G, Fernández R, Gordo F, Albert RK (2003) Prone vs supine position in ARDS patients. Results of a randomized multicenter trial. Am J Respir Crit Care Med 167:A180 (abst)

    Article  Google Scholar 

  17. Chatte G, Sab JM, Dubois JM, Sirodot M, Gaussorgues P, Robert D (1997) Prone position in mechanically ventilated patients with severe acute respiratory failure. Am J Respir Crit Care Med 155:473–478

    PubMed  Google Scholar 

  18. Gattinoni L, Vagginelli F, Carlesso E, et al (2003) Prone-Supine Study Group Decrease in PaCO2 with prone position is predictive of improved outcome in acute respiratory distress syndrome. Crit Care Med 31:2727–2733

    Article  PubMed  Google Scholar 

  19. Milberg JA, Davis DR, Steinberg KP, Hudson LD (1995) Improved survival in patients with acute respiratory syndrome. JAMA 273:306–309

    Article  PubMed  Google Scholar 

  20. Tobin MJ (1994) Mechanical ventilation. N Engl J Med 330:1056–1061

    Article  PubMed  Google Scholar 

  21. Laffey J, O'Croinin D, McLoughlin P, Kavanagh B (2004) Permissive hypercapnia. Role in protective lung ventilatory strategies. Intensive Care Med 30:347–356

    Article  PubMed  Google Scholar 

  22. Jorgensen EO, Holm S (1999) The course of circulatory and cerebral recovery after circulatory arrest: influence of prearrest, arrest and postarrest factors. Resuscitation 42:173–182

    Article  PubMed  Google Scholar 

  23. Laffey JG, Kavanagh BP (1999) Carbon dioxide and the critically ill — too little of a good thing? Lancet 354:1283–1286

    PubMed  Google Scholar 

  24. Laffey JG, Tanaka M, Engelberts D, et al (2000) Therapeutic hypercapnia reduces pulmonary and systemic injury following in vivo lung reperfusion. Am J Respir Crit Care Med 162:2287–2294

    PubMed  Google Scholar 

  25. Adding LC, Agvald P, Persson MG, Gustafsson LE (1999) Regulation of pulmonary nitric oxide by carbon dioxide is intrinsic to the lung. Acta Physiol Scand 167:167–174

    Article  PubMed  Google Scholar 

  26. Shibata K, Cregg N, Engelberts D, Takeuchi A, Fedorko L, Kavanagh BP (1998) Hypercapnic acidosis may attenuate acute lung injury by inhibition of endogenous xanthine oxidase. Am J Respir Crit Care Med 158:1578–1584

    PubMed  Google Scholar 

  27. Takeshita K, Suzuki Y, Nishio K, et al (2003) Hypercapnic acidosis attenuates endotoxin-induced nuclear factor KB activation. Am J Respir Cell Mol Biol 29:124–132

    Article  PubMed  Google Scholar 

  28. Holmes JM, Duffner LA, Jappil JC (1994) The effect of raised carbon dioxide on developing rat retinal vasculature exposed to elevated oxygen. Curr Eye Res 13:779–782

    PubMed  Google Scholar 

  29. Broccard A, Hotchkiss J, Vannay Ch, et al (2001) Protective effects of hypercapnic acidosis on ventilator-induced lung injury. Am J Respir Crit Care Med 164:802–806

    PubMed  Google Scholar 

  30. Sinclair S, Kregenow D, Lamn W, Starr I, Chi E, Hlastala M (2002) Hypercapnic acidosis is protective in an in vivo model of ventilator-induced lung injury. Am J Respir Crit Care Med 166:403–408

    Article  PubMed  Google Scholar 

  31. Laffey J, Engelberts D, Kavanach B (2000) Buffering hypercapnic acidosis worsens acute lung injury. Am J Respir Crit Care Med 161:141–146

    PubMed  Google Scholar 

  32. Lang JD Jr, Chumley P, Eiserich JP, et al (2000) Hypercapnia induces injury to alveolar epithelial cells via a nitric oxide-dependent pathway. Am J Physiol Lung Cell Mol Physiol 279:L994–L1002

    PubMed  Google Scholar 

  33. Zhu S, Basiouny KF, Crow JP, Matalon S (2000) Carbon dioxide enhances nitration of surfactant protein A by activated alveolar macrophages. Am J Physiol Lung Cell Mol Physiol 278:L1025–L1031

    PubMed  Google Scholar 

  34. Gores GJ, Nieminen AL, Fleishman KE, Dawson TL, Herman B, Lemasters JJ (1998) Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes. Am J Physiol 255:C315–C322

    Google Scholar 

  35. Weber T, Tschernich H, Sitzwohl C, et al (2000) Tromethamine buffer modifies the depressant effect of permissive hypercapnia on myocardial contractility in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 162:1361–1365

    PubMed  Google Scholar 

  36. Marini JJ, Hotchkiss J, Broccard A (2003) Bench-tobedside review: Microvascular and airspace linkage in ventilator-induced lung injury. Crit Care 7:435–444

    Article  PubMed  Google Scholar 

  37. Broccard A, Hotchkiss JR, Suzuki S, Olson D, Marini JJ (1999) Effects of mean airway pressure and tidal excursion on lung injury induced by mechanical ventilation in an isolated perfused rabbit lung moodel. Crit Care Med 27:1533–1541

    Article  PubMed  Google Scholar 

  38. Broccard A, Hothchkiss JR, Kuwayama N, et al (1998) Consequences of vascular flow on lung injury induced by mechanical ventilation. Am J Respir Crit Care Med 157:1935–1942

    PubMed  Google Scholar 

  39. Hohtchkiss JR, Blanch LL, Murias G, et al (2000) Effects of decreased respiratory frequency on ventilator induced lung injury. Am J Respir Crit Care Med 161:463–468

    PubMed  Google Scholar 

  40. Hotchkiss JR, Blanch LL, Naviera A, Adams AB, Olson D, Marini JJ (2001) Relative roles of vascular and airspace pressures in ventilator induced lung injury. Crit Care Med 29:1593–1598

    Article  PubMed  Google Scholar 

  41. Dreyfuss D, Saumon G (1998) Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 157:294–323

    PubMed  Google Scholar 

  42. Dreyfuss D, Saumon G (1993) Role of the tidal volume, FRC, and end-inspiratory volume in the development of pulmonary edema following mechanical ventilation. Am Rev Respir Dis 148:1194–1203

    PubMed  Google Scholar 

  43. Broccard A, Vannay Ch, Feihl F, Schaller M (2002) Impact of low pulmonary vascular pressure on ventilator induced lung injury. Crit Care Med 30:2183–2190

    Article  PubMed  Google Scholar 

  44. West JB (1962) Regional differences in gas exchange in the lung of erect man. J Appl Physiol 17:893–901

    PubMed  Google Scholar 

  45. Bernard SA, Gray TW, Buist MD, et al (2002) Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 346:557–563

    Article  PubMed  Google Scholar 

  46. Suzuki S, Hotchkiss JR, Toshimichi T, Olson D, Adams AB, Marini JJ (2004) Effect of core body temperature on ventilator-induced lung injury. Crit Care Med 32:144–149

    Article  PubMed  Google Scholar 

  47. McCormick PH, Chen G, Tlerney S, Kelly CJ, Bouchier-Hayes DJ (2003) Clinically relevant thermal preconditioning attenuates ischemia-reperfusion injury. J Surg Res 109:24–30

    Article  PubMed  Google Scholar 

  48. Yoo CG, Lee S, Lee CT (2000) Anti-inflammatory effect of HSP induction. J Immunol 164:5416–5423

    PubMed  Google Scholar 

  49. Ribeiro S, Rhee K, Tremblay L, Veldhuizen R, Lewis J, Slutsky A (2001) Heat stress attenuates ventilator-induced lung dysfunction in an ex vivo rat lung model. Am J Respir Crit Care Med 163:1451–1456

    PubMed  Google Scholar 

  50. Villar J, Ribeiro SP, Mullen JB, Kuliszewski M, Post M, Slutsky AS (1994) Induction of the heat shock response reduces mortality rate and organ damage in a sepsis-induced acute lung injury model. Crit Care Med 22:914–921

    PubMed  Google Scholar 

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Authors
  1. L.E. Ferrer
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  2. J.J. Marini
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Editor information

Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Head) (Head)

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© 2005 Springer-Verlag Berlin Heidelberg

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Ferrer, L., Marini, J. (2005). Modulators of Ventilator-induced Lung Injury. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2005. EN]Yearbook of Intensive Care and Emergency Medicine, vol 2005. Springer, New York, NY. https://doi.org/10.1007/0-387-26272-5_11

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  • DOI: https://doi.org/10.1007/0-387-26272-5_11

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-3-540-23476-0

  • Online ISBN: 978-0-387-26272-7

  • eBook Packages: MedicineMedicine (R0)

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