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Oxygen Transport to Tissue XXVI pp 285–294Cite as

Exogenous and Endogenous Markers of Tumour Oxygenation Status

Definitive markers of tumour hypoxia?

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 566))

Abstract

Hypoxia is a physiological abnormality that has been detected in all solid tumours analysed to date. Studies using polarographic needle electrodes have shown an unequivocal link between the extent of tumour hypoxia and poor treatment outcome. The practical limitations of polarographic needle electrodes have warranted investigation into alternative strategies enabling routine assessment of tumour hypoxia in the clinical setting. This review focuses on the clinical evaluation of exogenous and endogenous markers of tumour hypoxia that may fulfil this role.

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Authors
  1. Kaye J. Williams
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  2. Catriona A. Parker
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  3. Ian J. Stratford
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Editors and Affiliations

  1. Department of Radiation Oncology, University of Rochester, Rochester, NY, 14642, USA

    Paul Okunieff , Jacqueline Williams  & Yuhchyau Chen ,  & 

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Williams, K.J., Parker, C.A., Stratford, I.J. (2005). Exogenous and Endogenous Markers of Tumour Oxygenation Status. In: Okunieff, P., Williams, J., Chen, Y. (eds) Oxygen Transport to Tissue XXVI. Advances in Experimental Medicine and Biology, vol 566. Springer, Boston, MA. https://doi.org/10.1007/0-387-26206-7_38

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