Advertisement

Validation of the Cas Neonatal NIRS System by Monitoring VV-ECMO Patients

Preliminary results
  • Paul B. Benni
  • Bo Chen
  • Francine D. Dykes
  • Scott F. Wagoner
  • Micheal Heard
  • April J. Tanner
  • Teresa L. Young
  • Khodayar Rais-Bahrami
  • Oswaldo Rivera
  • Billie L. Short
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 566)

Abstract

The CAS neonatal NIRS system determines absolute regional brain tissue oxygen saturation (SnO2) and brain true venous oxygen saturation (SnvO2) non-invasively. Since NIRS-interrogated tissue contains both arterial and venous blood from arterioles, venules, and capillaries, SnO2 is a mixed oxygen saturation parameter, having values between arterial oxygen saturation (SaO2) and cerebral venous oxygen saturation (SVO2). To determine a reference for SnO2, the relative contribution of SvO2 to SaO2 drawn from a brain venous site vs. systemic SaO2 is approximately 70:30 (SvO2:SaO2). If the relationship of the relative average contribution of SvO2 and SaO2 is known and does not change to a large degree, then NIRS true venous oxygen saturation, SnvO2, can be determined non-invasively using SnO2 along with SaO2 from a pulse oximeter.

Keywords

Oxygen Saturation Pulse Oximeter Arterial Oxygen Saturation Data Segment Brain Oxygenation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    P. B. Benni, Method for non-invasive spectrophotometric blood oxygenation monitoring, U.S. Patent No. 6,456,862, USPTO, (2002).Google Scholar
  2. 2.
    R. Pettignano, M. Labuz, T. Gauthier, J. Huckaby, and R. Clark, The use of cephalad cannulae to monitor jugular venous oxygen content during extracorporeal membrane oxygenation, Crit. Care 1(3), 95–99 (1997).PubMedCrossRefGoogle Scholar
  3. 3.
    N. C. Brun, A. Moen, K. Borch, O. D. Saugstad, and G. Greisen, Near-infrared monitoring of cerebral tissue oxygen saturation and blood volume in newborn piglets, Am. J. Physiol. 273(2 Pt. 2), H682–H686 (1997).PubMedGoogle Scholar
  4. 4.
    H. M. Watzman, C. D. Kurth, L. M. Montenegro, J. Rome, J. M. Steven, and S. C. Nicolson, Arterial and venous contributions to near-infrared cerebral oximetry, Anesthesiol. 93(4), 947–953 (2000).CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • Paul B. Benni
  • Bo Chen
  • Francine D. Dykes
  • Scott F. Wagoner
  • Micheal Heard
  • April J. Tanner
  • Teresa L. Young
  • Khodayar Rais-Bahrami
  • Oswaldo Rivera
  • Billie L. Short

There are no affiliations available

Personalised recommendations