Abstract
Characterizing the differences in kindling rates and associated convulsive behaviors following kindling of various structures may aid in understanding the structural and functional mechanisms of epileptogenesis. Overall, the structures and pathways that are critical to kindling are largely unknown. The results of recent research suggest a role for the CLA, namely that the CLA may be part of a network of structures involved in seizure generalization. The anterior CLA is highly susceptible to kindling, involving a pattern of dual-phase seizure development.1
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
6. References
X. Zhang, D. K. Hannesson, D M. Saucier, A.E. Wallace, J. Howland and ME. Corcoran, Susceptibility to kindling and neuronal connections of the anterior claustrum, J. Neurosci. 21, 3674–3687 (2001).
M.E. Corcoran, “Characteristics and mechanisms of kindling”, in Sensitization of the nervous system, edited by p. Kalivas and C. Barnes (The Telford Press, Caldwell, NJ, 1988), pp. 81–116.
D. P. Cain and M. E. Corcoran, Kindling with low-frequency stimulation: generality, transfer, and recruiting effects, Exp. Neurol. 73, 219–32 (1981).
W. T. Seidel and M. E. Corcoran, Relations between amygdaloid and anterior neocortical kindling, Brain Res. 385, 375–378 (1986).
D. P. Cain, Kindling in sensory systems: thalamus, Exp. Neurol., 66, 319–329 (1979).
Y. Wada, Y. Minabe, H. Okuda, I. Jibiki, K. Yoshida and N. Yamaguchi, Lateral geniculate kindling and long-lasting photosensitivity in cats, Exp. Neurol. 91, 343–354 (1986).
M. E. Corcoran and D. P. Cain, Kindling of seizures with low-frequency electrical stimulation, Brain Res. 196, 262–265 (1980).
D. P. Cain, D. J. McKitrick and F. Boon, Rapid and reliable induction of partial status epilepticus in naive rats by low-frequency (3-Hz) stimulation of the amygdale, Epilepsy. Res. 12, 51–55 (1992).
J. L. Burchfiel and C. D. Applegate, Stepwise progression of kindling: perspectives from the kindling antagonism model, Neurosci. Biobehav. Rev. 13, 289–99 (1989).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer Science+Business Media, Inc.
About this paper
Cite this paper
Sheerin, A., Zhang, X., Saucier, D., Corcoran, M. (2005). Involvement of the Claustrum and Ventromedial Thalamus in Epileptogenesis. In: Corcoran, M.E., Moshé, S.L. (eds) Kindling 6. Advances in Behavioral Biology, vol 55. Springer, Boston, MA. https://doi.org/10.1007/0-387-26144-3_12
Download citation
DOI: https://doi.org/10.1007/0-387-26144-3_12
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-24380-1
Online ISBN: 978-0-387-26144-7
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)