Gene Regulation in Eukaryotes

Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)


Core Promoter Translation Initiation Factor Histone Tail Preinitiation Complex Leucine Zipper Domain 
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References and Further Reading

Promoter Architecture

  1. Bell AC, West AG, and Felsenfeld G [2001]. Insulators and boundaries: Versatile regulatory elements in the eukaryotic genome. Science, 291: 447–450.CrossRefADSGoogle Scholar
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Structure of RNAP II

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  2. Gnatt AL, et al. [2001]. Structural basis of transcription: An RNA Polymerase II elongation complex at 3.3 Åresolution. Science, 292: 1876–1882.CrossRefADSGoogle Scholar
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Chromatin-Modifying Enzymes

  1. Boyer LA, et al. [2000]. Functional delineation of three groups of the ATP-dependent family of chromatin remodeling enzymes. J. Biol. Chem., 275: 18864–18870.CrossRefGoogle Scholar
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Mediator Complexes

  1. Asturias FJ, et al. [1999]. Conserved structures of Mediator and RNA polymerase holoenzyme. Science, 283: 985–987.CrossRefADSGoogle Scholar
  2. Boube M, et al. [2002]. Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man. Cell, 110: 143–151.CrossRefGoogle Scholar
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  6. Taatjes DJ, et al. [2002]. Structure, function, and activator-induced conformations of the CRSP coactivator. Science, 295: 1058–1062.CrossRefADSGoogle Scholar


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Alternative Splicing

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Regulation of Translation Initiation

  1. Dever TE [2002]. Gene-specific regulation by general translation factors. Cell, 108: 545–586.CrossRefGoogle Scholar
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  6. Proud CG [2002]. Regulation of mammalian translation factors by nutrients. Eur. J. Biochem., 269: 5338–5349.CrossRefGoogle Scholar
  7. Wang XM, et al. [2003]. The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation. Mol. Cell. Biol., 23: 1546–1557.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2005

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