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Inflammatory Bowel Disease

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Abstract

Inflammatory bowel disease (IBD) is an inflammatory disease of the digestive tract, which includes three distinct diagnoses categories: ulcerative colitis (UC), Crohn’s disease (CD) and indeterminate colitis (IC). IBD is characterized by symptoms of abdominal pain, fatigue, weight loss, diarrhea, cramping, and joint pain. These symptoms often interfere with everyday life and can have long-term effects, such as delayed sexual maturity and growth retardation. In CD, the inflammation extends through the full thickness of the intestinal wall, and this inflammation may affect any part of the GI tract from the mouth to the skin around the anus. In UC, the inflammation is confined to the large intestine, and it is restricted to the inner lining of the colon. Figures 3.1 and 3.2 diagram the different areas of inflammation in CD and UC in children.

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(2006). Inflammatory Bowel Disease. In: Pediatric Gastrointestinal Disorders. Springer, Boston, MA. https://doi.org/10.1007/0-387-25612-1_3

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