Microfabrication and Application of Recessed Gold Electrodes in Microchip Electrophoresis System

Abstract

Based on photolithographic technique, a simple and novel way to construct micro recessed gold electrodes (μRGE) using recordable compact disk was described in this paper. μRGE were characterized by a remarkable versatility, great availability, good reproducibility, insensitive response to the fluctuation of flow speed, and very low price. The applicability of μRGE in microchip electrophoresis system was demonstrated for the anodic detection of dopamine and catechol. A high sensitivity and low noise was obtained, consequently a lower detection limit (0.31 for dopamine and 0.62 µ mol/L for catechol) was achieved, which was far lower than that reported in the literature.