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The Neuron and Axon in Experimental Autoimmune Encephalomyelitis

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Experimental Models of Multiple Sclerosis

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Abstract

Neuronal and axonal loss and damage are increasingly recognized major pathological features of MS that correlate with disability. Correspondingly, in EAE, these processes are being investigated in great detail. This chapters discusses the present knowledge of axonal and neuronal pathology in MS and details the relevant studies in EAE, that may form the basis to future neuroprotective/regenerative approaches to MS.

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Authors and Affiliations

  1. Division of Clinical Neurology, University of Nottingham, UK

    Nikos Evangelou & Cris S Constantinescu

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  1. Nikos Evangelou
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  2. Cris S Constantinescu
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Editors and Affiliations

  1. Weill Medical College of Cornell University, New York

    Ehud Lavi

  2. Queen’s Medical Centre, University Hospital, Nottingham, UK

    Cris S. Constantinescu

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Evangelou, N., Constantinescu, C.S. (2005). The Neuron and Axon in Experimental Autoimmune Encephalomyelitis. In: Lavi, E., Constantinescu, C.S. (eds) Experimental Models of Multiple Sclerosis. Springer, Boston, MA. https://doi.org/10.1007/0-387-25518-4_8

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