Abstract
The single most important clinically relevant cause of global cerebral ischemia is cardiac arrest. Other causes like hanging will not be covered in this chapter. The estimated rate of sudden cardiac arrest lies between 40 to 130 cases per 100,000 people per year in industrialized countries (1,2). Unfortunately full cerebral recovery is still a rare event. Almost 80% of patients who initially are resuscitated fiom cardiac arrest remain comatose for more than one hour. One year after cardiac arrest only 10–30% of these patients survive with good neurological outcome (3). Current therapy after cardiac arrest has concentrated on resuscitation efforts (4) but until recently no specific therapy for brain resuscitation was available.
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Holzer, M., Bernard, S.A., Sterz, F. (2005). Global Cerebral Ischemia: Clinical Studies. In: Tisherman, S.A., Sterz, F. (eds) Therapeutic Hypothermia. Molecular and Cellular Biology of Critical Care Medicine, vol 4. Springer, Boston, MA. https://doi.org/10.1007/0-387-25403-X_2
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DOI: https://doi.org/10.1007/0-387-25403-X_2
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