Abstract
Indirect imaging systems such as SPECT have three essential components: an image-forming element, an image detector, and a reconstruction algorithm. These components act together to transfer information about the object to the end user or observer, which can be a human or a computer algorithm. As we shall see in Chapter 5, the efficacy of this information transfer can be quantified and used as a figure or merit for the overall imaging system or for any component of it. Fundamentally, image quality is defined by the ability of some observer to perform some task of medical or scientific interest.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
C. K. Abbey, H. H. Barrett, “Linear iterative reconstruction algorithms: Study of observer performance,” XIVth International Conference on Information Processing in Medical Imaging (IPMI), Ile de Berder, France, pp. 65–76, June 26–30, 1995.
C.K. Abbey, H.H. Barrett, D.W. Wilson, “Observer signal-to-noise ratios for the ML-EM algorithm,” Proc SPIE, vol. 2708, 1996.
R. Accorsi, F. Gasparini, R. C. Lanza, “A Coded Aperture for High-Resolution Nuclear Medicine Planar Imaging with a Conventional Anger Camera: experimental results,” IEEE Trans Nucl Sci, vol. 48, no. 6, pp. 2411–2417, December 2001a.
R. Accorsi, F. Gasparini, R. C. Lanza, “Optimal Coded Patterns for Improved SNR in Nuclear Medicine Imaging,” Nucl Instr Meth Phys Res A, vol. 474, pp. 273–284, 2001b.
H. H. Barrett, “Fresnel zone plate imaging in nuclear medicine,” J. Nucl Med, vol. 13, no. 6, pp. 382–385, 1972.
H.H. Barrett, W. Swindell, Radiological Imaging: Theory of Image Formation, Detection, and Processing, vols. I and II, New York, Academic Press, 1981.
H. H. Barrett, “Objective assessment of image quality: effects of quantum noise and object variability,” J. Opt Soc Am A, vol. 7, pp. 1266–1278, 1990.
H.H. Barrett, H. C. Gifford, “Cone-beam tomography with discrete data sets,” Phys Med Biol, vol. 39, pp. 451–476, 1994.
H. H. Barrett, J. L. Denny, R. F. Wagner, K. J. Myers, “Objective assessment of image quality. II Fisher information, Fourier crosstalk, and figures of merit for task performance,” J. Opt Soc Am A, vol. 12, no. 5, pp. 834–852, 1995a.
H. H. Barrett, J. D. Eskin, H. B. Barber, “Charge transport in arrays of semiconductor gamma-ray detectors,” Phys Rev Lett, vol. 5, no. 1, pp. 156–159, 1995b.
H. H. Barrett, J. L. Denny, H. C. Gifford, C. K. Abbey, “Generalized NEQ: Fourier analysis where you would least expect to find it,” Proc SPIE, vol. 2708, pp. 41–52, 1996a.
H. H. Barrett, W. Swindell, Radiological Imaging: Theory of Image Formation, Detection, and Processing, Paperback edition, New York, Academic Press, 1996b.
H. H. Barrett, B. Gallas, E. Clarkson, A. Clough, “Scattered radiation in nuclear medicine: A case study in the Boltzmann transport equation,” Computational Radiology and Imaging: Therapy and Diagnosis, Borgers, C., Natterer, F. eds., Springer Verlag, 1998.
H. H. Barrett, K. J. Myers, Foundations of Image Science, New York, John Wiley and Sons, 2004.
A. J. Bird, T. Carter, A. J. Dean, D. Ramsden, B. M. Swinyard, “The optimisation of small CsI(Tl) gamma-ray detectors,” IEEE Trans Nucl Sci, vol. 40, no. 4, pp. 395–399, 1993.
A. Breskin, A. Buzulutskov, R. Chechik, B. K. Singh, A. Bondar, L. Shekhtman, “Sealed GEM photomultiplier with a CsI photocathode,” Nucl Instr Meth Phys Res A, vol. 478, pp. 225–229, 2002.
J. C. Chen, “Scatter Rejection in Gamma Cameras for Use in Nuclear Medicine,” Biomed Eng Appl Basis Comm, vol. 9, pp. 20–26, 1997.
Y. H. Chung, Y. Choi, G. Cho, Y. S. Choe, K.-H. Lee, B.-T. Kim, “Optimization of Dual Layer Phoswich Detector Consisting of LSO and LuYAP for Small Animal PET,” Proc IEEE Med Imag Conf, 2003.
E. Clarkson, D. W. Wilson, H. H. Barrett, “The synthetic collimator for 2D and 3D imaging,” Proc SPIE Med Imag, vol. 3659, pp. 107–117, 1999.
S. E. Derenzo, W.W. Moses, “Experimental efforts and results in finding new heavy scintillators,” Heavy Scint for Sci and Indust Apps, De Notaristefani, F., LeCoq, P., Schneegans, M. eds., Gif-sur-Yvette, France, Editions Frontieres, pp. 125–135, 1993.
A. P. Dhanasopon, C. S. Levin, A.M.K. Foudray, P.D. Olcott, J. A. Talcott, F. Habte, “Scintillation Crystal Design Features for a Miniature Gamma Ray Camera,” Proc IEEE Med Imag Conf, 2003.
P. Dorenbos, J. T. M. de Haas, C. W. E. van Eijk, “Nonproportinoality in Scintillator Response and Energy Resolution Obtainable with Scintillator Crystals,” IEEE Trans Nucl Sci, vol. 42, pp. 2190–2202, 1995.
J. D. Eskin, H. H. Barrett, H. B. Barber, “Signals induced in semiconductor gamma-ray imaging detectors,” J. Appl Phys, vol. 85, pp. 647–659, 1999.
L. R. Furenlid, E. Clarkson, D. G. Marks, H. H. Barrett, “Spatial pileup considerations for pixellated gamma-ray detectors,” IEEE Trans Nucl Sci, vol. 47, pp. 1399–1402, 2000.
E. Gatti, P. Rehak, “Semiconductor drift chamber — an application of a novel charge transport scheme,” Nucl Instr Meth, vol. 225, pp. 608–614, 1984.
D. L. Gunter, “Collimator Characteristics and Design.” In Nuclear Medicine, Henken, R. E., ed., Mosby Year Book, St. Louis, Chap. 8., 1996.
T. Hadig, J. Schwiening, C. Field, G. Mazaheri, M. Jain, D. G. W. S. Leith, B. Ratcliff, J. Va’vra, “Study of Timing and Efficiency Properties of the Hamamatsu H-8500 Photomultiplier,” Proc IEEE Nucl Sci Symp, 2002.
N. Inadama, H. Murayama, M. Watanabe, T. Omura, T. Yamashita, H. Kawai, N. Orita, T. Tsuda, “Performance of 256ch flat panel PSPMT with small crystals for a DOI PET detector,” Proc IEEE Med Imag Conf, 2003.
R. J. Jaszczak, J. Li, H. Wang, M. R. Zallutsky, R. E. Coleman, “Pinhole collimation for ultra-high resolution, small-field-of-viewSPECT studies,” Phys Med Biol, vol. 39, pp. 425–437, 1994.
G. F. Knoll, Radiation Detection and Measurement, 3rd ed., New York, Wiley, 1999.
D. P. Kwo, H. B. Barber, H. H. Barrett, T. S. Hickernell, J. M. Woolfenden, “Comparison of NaI(Tl), HgI2 and CdTe surgical probes II: Effect of scatter compensation on probe performance,” Med Phys, vol. 18, pp. 382–389, 1991.
D. G. Marks, H. B. Barber, H. H. Barrett, J. Tueller, J. M. Woolfenden, “Improving performance of a CdZnTe imaging array by mapping the detector with gamma rays,” Nucl Instr Meth Phys Res A, vol. 428, pp. 102–112, 1999.
J. L. Matteson, W. Coburn, F. Duttweiler, W. A. Heindl, G. L. Huszar, P. C. LeBlanc, M. R. Pelling, L. E. Peterson, R. E. Rothschild, R. T. Skelton, P. L. Hink, C. Crabtree, “CdZnTe arrays for astrophysics applications,” Proc SPIE, vol. 3115, pp. 160–175, 1997.
V. R. McCready, R. P. Parker, E. M. Gunnersen, R. Ellis, E. Moss, W. G. Gore, “Clinical tests with a prototype semiconductor gamma camera,” Brit J. Radiology, vol. 44, pp. 58, 1971.
S. R. Meikle, R. Wojcik, A. G. Weisenberger, M. F. Smith, S. Majewski, P. Kench, S. Eberl, R. R. Fulton, M. Lerch, A. B. Rosenfeld, “CoALA-SPECT: A coded aperture laboratory animal SPECT system for preclinical imaging,” 2002 IEEE Nucl Sci Symp Conference Record, Scott Metzler, ed., Norfolk, Virginia, ISBN 0-7803-7637-4, November 10–16, 2002a.
S. R. Meikle, P. Kench, A. G. Weisenberger, R. Wojcik, M. F. Smith, S. Majewski, S. Eberl, R. R. Fulton, A. B. Rosenfeld, M. J. Fulham, “A prototype coded aperture detector for small animal SPECT,” IEEE Trans Nucl Sci, vol. 49, pp. 2167–2171, 2003b.
D. Mörmann, A. Breskin, R. Chechik, P. Cwetanski, B.K. Singh, “Gas avalanche photomultiplier with a CsI-coated GEM,” Nucl InstrMeth Phys Res A, vol. 478, pp. 230–234, 2002.
W. W. Moses, S. E. Derenzo, “Design studies for a PET detector module using a pin photodiode to measure depth of interaction,” IEEE Trans Nucl Sci, vol. 41, no. 4, pp. 1441–1445, August 1994.
W.W. Moses, S. E. Derenzo, C. L. Melcher, R.A. Manente, “A room temperature LSO/pin photodiode PET detector module that measures depth of interaction,” IEEE Trans Nucl Sci, vol. 42, no. 4, pp. 1085–1089, August 1995.
W. W. Moses, “Current trends in scintillator detectors and materials,” Nucl Instr Meth Phys Res A, vol. 487, pp. 123–128, 2002.
G. Muehllehner, “Effect of resolution improvement on required count density in ECT imaging: a computer simulation,” Phys Med Biol, vol. 30, no. 2, pp. 163–173, 1985.
S. P. Müller, J. F. Polak, M. F. Kijewski, B. L. Holman, “Collimator Selection for SPECT Brain Imaging: The Advantage of High Resolution,” J. Nucl Med, vol. 27, pp. 1729–1738, 1986.
K. J. Myers, J. P. Rolland, H. H. Barrett, R. F. Wagner, “Aperture optimization for emission imaging: Effect of a spatially varying background,” J. Opt Soc Am A, vol. 7, pp. 1279–1293, 1990.
N. Orita, H. Murayama, H. Kawai, N. Inadama, T. Tsuda, “Three Dimensional Array of Scintillation Crystals with Proper Reflector Arrangement for a DOI detector,” Proc IEEE Med Imag Conf, 2003.
R. Pani, R. Pellegrini, M. N. Cinti, C. Trotta, G. Trotta, R. Scafe, M. Betti, F. Cusanno, L. Montani, G. Iurlaro, F. Garibaldi, Del A. Guerra, “A novel compact gamma camera based on flat panel PMT,” Nucl Instr Meth Phys Res A, vol. 513, no. 1, pp. 36–41, 2003.
R. Pani, R. Pellegrini, M. N. Cinti, M. Mattioli, C. Trotta, L. Montani, G. Iurlaro, G. Trotta, D’L. Addio, S. Ridolfi, De G. Vincentis, I. N. Weinberg, “Recent advances and future perspectives of position sensitive PMT,” Nucl Instr Meth Phys Res B, vol. 213, pp. 197–205, 2004.
V. Radeka, “Low-noise techniques in detectors,” Ann RevNucl Part Sci, vol. 38, pp. 217–277, 1988.
P. A. Rodnyi, “Core-valence band transitions in wide-gap ionic crystals,” Sov Phys Solid State, vol. 34, pp. 1053–1066, 1992
M. M. Rogulski, H. B. Barber, H. H. Barrett, R. L. Shoemaker, J. M. Woolfenden, “Ultra-high-resolution brain SPECT: simulation results,” IEEE Trans Nucl Sci, vol. 40, pp. 1123–1129, 1993.
J. P. Rolland, H. H. Barrett, G. W. Seeley, “Quantitative study of deconvolution and display mappings for long-tailed point-spread functions,” Proc SPIE, vol. 1092, pp. 17–21, 1989.
J. P. Rolland, Factors influencing lesion detection inmedical imaging, Ph.D. Dissertation, University of Arizona, Tucson, Arizona, 1990.
J. P. Rolland, H. H. Barrett, G. W. Seeley, “Ideal versus human observer for long-tailed point spread functions: Does deconvolution help?” Phys Med Biol, vol. 36, no. 8, pp. 1091–1109, 1991.
J. P. Rolland, H. H. Barrett, “Effect of random background inhomogeneity on observer detection performance,” J. Opt Soc Am A, vol. 9, no. 5, pp. 649–658, 1992.
J. M. Ryan, J. R. Macri, M. L. McConnell, B. K. Dann, M. L. Cherry, T.G. Guzik, F. P. Doty, B.A. Apotovsky, J. F. Butler, “Large area sub-millimeter resolution CdZnTe strip detector for astronomy,” Proc SPIE, vol. 301, pp. 2518:292, 1995.
N. Schramm, G. Ebel, U. Engeland, M. Behe, T. Schurrat, T. M. Behr, “Multi-pinhole SPECT for small animal research,” J. Nucl Med, vol. 43, no. 5, pp. S.913, 2002.
M. F. Smith, R. Jaszczak, “An analytic model of pinhole aperture penetration for 3D pinhole SPECT image reconstruction,” Phys Med Biol, vol. 43, pp. 761–775, 1998.
C. M. Stahle, A. Parsons, L. M. Bartlett, P. Kurczynski, J. F. Krizmanic, L.M. Barbier, S.D. Barthelmy, F. Birsa, N. Gehrels, J. Odom, D. Palmer, C. Sappington, P. Shu, Teegarden B. J., J. Tueller, “CdZnTe strip detector for arc second imaging and spectroscopy,” Proc Society Photo-Optical and Instr Eng, vol. 2859, pp. 74–84, 1996.
B. M. W. Tsui, C. E. Metz, F. B. Atkins, S. J. Starr, R. N. Beck, “A Comparison of Optimum Detector Spatial Resolution in Nuclear Imaging based on Statistical Theory and on Observer Performance,” Phys Med Biol, vol. 23, no. 4, pp. 654–676, 1978.
B.M.W. Tsui, C. E. Metz, Beck, R.N. “Optimum detector spatial resolution for discriminating between tumour uptake distributions scintigraphy,” Phys Med Biol, vol. 28, no. 7, pp. 775–788, 1983.
R. F. Wagner, D. G. Brown, “Unified SNR analysis of medical imaging systems,” Phys Med Biol, vol. 30, no. 6, pp. 489–518, 1985.
Y. J. Wang, B. E. Patt, J. S. Iwanczyk, S. R. Cherry, Y. Shao, “High efficiency CsI(Tl)/HgI2 2 gamma ray spectrometers,” IEEE Trans Nucl Sci, vol. 42, no. 4, pp. 601–605, 1995.
T. A. White, SPECT reconstruction directly from photomultiplier tube signals, Ph.D. Dissertation, University of Arizona, Tucson, Arizona, 1994.
M. J. Weber, “Inorganic scintillators: today and tomorrow,” J. Lums, vol. 100, pp. 35–45, 2002.
D. W. Wilson, E. W. Clarkson, H. H. Barrett, “Reconstruction of two-and three-dimensional images from synthetic collimator data,” IEEE Trans Med Im, vol. 19, no. 5, pp. 412–422, 2000.
van C. W. E. Eijk, “Inorganic scintillators in medical imaging,” Phys Med Biol, vol. 47, pp. R85–R106, April 21, 2002
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer Science+Business Media, Inc.
About this chapter
Cite this chapter
Barrett, H.H., Hunter, W.C.J. (2005). Detectors for Small-Animal SPECT I. In: Kupinski, M.A., Barrett, H.H. (eds) Small-Animal Spect Imaging. Springer, Boston, MA. https://doi.org/10.1007/0-387-25294-0_2
Download citation
DOI: https://doi.org/10.1007/0-387-25294-0_2
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-387-25143-1
Online ISBN: 978-0-387-25294-0
eBook Packages: EngineeringEngineering (R0)