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Characterisation of proteins in scent marks: Proteomics meets semiochemistry

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Chemical Signals in Vertebrates 10

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References

  • Aebersold, R., and Mann, M., 2003, Mass spectrometry-based proteomics, Nature 422:198–207.

    Article  PubMed  CAS  Google Scholar 

  • Altschul, S. F., Madden, T. L., Schlffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J., 1997, Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Res. 25:3389–3402.

    Article  PubMed  CAS  Google Scholar 

  • Ashcroft, A. E., 2003, Protein and peptide identification: the role of mass spectrometry in proteomics, Nat. Prod. Rep. 20:202–215.

    Article  PubMed  CAS  Google Scholar 

  • Beynon, R. J., and Bond, J. S., 1999, Proteolytic Enzymes a Practical Approach, IRL press, Oxford.

    Google Scholar 

  • Beynon, R. J., Veggerby, C., Payne, C. E., Robertson, D. H., Gaskell, S. J., Humphries, R. E., and Hurst, J. L., 2002, Polymorphism in major urinary proteins: molecular heterogeneity in a wild mouse population, J. Chem. Ecol. 28:1429–1446.

    Article  PubMed  CAS  Google Scholar 

  • Buck, L., and Axel, R., 1991, A novel multigene family may encode odorant receptors: a molecular basis for odour recognition, Cell 65:175–187.

    Article  PubMed  CAS  Google Scholar 

  • Chalmers, M. J., and Gaskell, S. J., 2000, Advances in mass spectrometry for proteome analysis, Curr. Opin. Biotechnol. 11:384–390.

    Article  PubMed  CAS  Google Scholar 

  • Clark, A. J., Ghazal, P., Bingham, R. W., Barrett, D., and Bishop, J. O., 1985, Sequence structures of a mouse major urinary protein gene and pseudogene compared, EMBO J. 4:3159–3165.

    PubMed  CAS  Google Scholar 

  • Cunningham, B. A., 1977, The structure and function of histocompatibility antigens, Sci. Am. 237:96–107.

    Article  PubMed  CAS  Google Scholar 

  • Emes, R. D., Goodstadt, L., Winter, E. E., and Ponting, C. P., 2003, Comparison of the genomes of human and mouse lays the foundation of genome zoology. Hum. Mol. Genet. 12:701–709.

    Article  PubMed  CAS  Google Scholar 

  • Finlayson, J. S., and Baumann, C. A., 1958, Mouse proteinuria, Amer. J. Physiol. 192:69–72.

    PubMed  CAS  Google Scholar 

  • Gershon, D., 2003, Proteomics technologies: Probing the proteome, Nature 424:581–587.

    Google Scholar 

  • Hayter, J. R., Robertson D. H. L., Gaskell, S. J., and Beynon R. J., 2003, Proteome analysis of intact proteins in complex mixtures, Mol. Cell. Proteom. 2:85–95.

    Article  CAS  Google Scholar 

  • Humphries, R., Hurst, J. L., Robertson, D. H. L., and Beynon R. J., 1999, Unravelling the chemical basis of competitive scent marking in house mice, Anim. Behav. 58:1177–1190.

    Article  PubMed  Google Scholar 

  • Hurst, J. L., Robertson, D. H. L., Tolladay, U., and Beynon, R. J., 1998, Lipocalins in mouse urine provide a slow release mechanism for olfactory signals, Anim. Behav. 55:1289–1297.

    Article  PubMed  Google Scholar 

  • Hurst, J. L., Payne, C. E., Nevison, C. M., Marie, A. D., Humphries, R. E., Robertson D. H. L., Cavaggioni, A., and Beynon, R. J., 2001, Major urinary proteins play a key role in the mechanism of individual recognition in mice, Nature 414:631–634.

    Article  PubMed  CAS  Google Scholar 

  • Kikuyama, S., and Toyoda, F., 1999, Sodefrin: a novel sex pheromone in a newt, Rev. Reprod. 4: 1–4.

    Article  PubMed  CAS  Google Scholar 

  • Klein, J., 1979, The major histocompatibility complex of the mouse, Science 213:516–521.

    Article  Google Scholar 

  • Laemmlli, U. K., 1970, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227:680–685.

    Article  Google Scholar 

  • Lin, D., Tabb, D. L. and Yates, J. R., 2003, Large-scale protein identification using mass spectrometry, Biochim. Biophys. Acta. 1646: 1–10.

    PubMed  CAS  Google Scholar 

  • Marie A. D., Veggerby C., Robertson D. H., Gaskell S. J., Hubbard S. J., Martinsen L., Hurst J. L., and Beynon R. J., 2001, Effect of polymorphisms on ligand binding by mouse major urinary proteins, Protein Sci. 10:411–417.

    Article  CAS  Google Scholar 

  • Mechref, Y., Zidek, L., Ma, W., and Novotny, M. V., 2000, Glycosylated major urinary protein of the house mouse: characterization of its N-linked oligosaccharides, Glycobiology 10:231–235.

    Article  PubMed  CAS  Google Scholar 

  • Mertens, B., Vandoren, G., Opdenakker, G., Volckaert, G., and Verhoeven, G., 1983, Heterogeneity of alpha 2u-globulin gene products in different translational systems, plasma and urine, FEBS Lett. 162: 296–299.

    Article  PubMed  CAS  Google Scholar 

  • Nguyen, N. Y., Salokangas, A., and Chrambach, A., 1977, Electrofocusing in natural pH gradients formed by buffers: gradient modification, Anal. Biochem. 78:287–294.

    Article  PubMed  CAS  Google Scholar 

  • Parfentjev, J. A., and Perlzweig, W. A., 1933, The comparison of the urine of white mice, J. Biol. Chem. 100:551–555.

    CAS  Google Scholar 

  • Perkins, D. N., Pappin, D. J., Creasy, D.M., and Cottrell, J.S., 1999, Probability-based protein identification by searching sequence databases using mass spectrometry data, Electrophoresis 20:3551–3567.

    Article  PubMed  CAS  Google Scholar 

  • Pevsner, J., Hou, V., Snowman, A. M., and Snyder, S.H., 1990, Odorant binding protein: characterisation of ligand binding, J. Biol. Chem. 265:6118–6125.

    PubMed  CAS  Google Scholar 

  • Rasmussen, L. E., 2001, Source and cyclic release pattern of (Z)-7-dodecenyl acetate, the pre-ovulatory pheromone of the female Asian elephant, Chem. Senses 26:611–623.

    Article  PubMed  CAS  Google Scholar 

  • Robertson, D. H. L., Beynon, R. J., and Evershed, R. P., 1993, Extraction, characterisation and binding analysis of two pheromonally active ligands associated with the major urinary protein of the house mouse (Mus musculus), J. Chem. Ecol. 19:1405–1416.

    Article  CAS  Google Scholar 

  • Robertson, D. H. L., Evershed, R. P., Cox, K., Gaskell, S., and Beynon, R.J., 1996, Molecular heterogeneity of urinary proteins of the house mouse Mus musculus. Biochem. J. 316: 265–272.

    PubMed  CAS  Google Scholar 

  • Robertson, D. H. L., Hurst, J. L., Bolgar, M. S., Gaskell, S. J., and Beynon, R.J., 1997, Molecular heterogeneity of urinary proteins in wild house mouse populations, Rap. Comm. Mass Spec. 11:786–790.

    Article  CAS  Google Scholar 

  • Robertson, D. H. L. Marie, A. D., Veggerby, C., Hurst J. L., and Beynon, R.J., 2001, Characteristics of ligand binding and release by major urinary proteins, in: Chemical Signals in Vertebrates 9 A. Marchlewska-Koj, J.J. Lepri and D. Muller-Schwarze, eds., Kluwer Academic/Plenum Publishers, New York, pp. 169–176.

    Google Scholar 

  • Ronnett, G. V. and Moon, C., 2002, G proteins and olfactory signal transduction, Annu. Rev. Physiol. 64:189–222.

    Article  PubMed  CAS  Google Scholar 

  • Schwende, F. J., Weisler, D., Jorgenson, J. W., Carmack, M., and Novotny, M., 1986, Urinary volatile constituents of the house mouse Mus musculus and their endocrine dependency, J. Chem. Ecol. 12: 277–296.

    Article  CAS  Google Scholar 

  • Seybold, S. J., and Tittiger, C., 2003, Biochemistry and molecular biology of de novo isoprenoid pheromone production in the Scolytidae, Ann. Rev. Entomol. 48:425–453.

    Article  CAS  Google Scholar 

  • Sharrow, S. D., Vaughn, J. L., Zidek, L., Novotny, M. V., and Stone, M. J., 2002, Pheromone binding by polymorphic mouse major urinary proteins, Protein Sci. 11:2247–2256.

    Article  PubMed  CAS  Google Scholar 

  • Sharrow, S. D., Novotny, M. V. and Stone, M. J., 2003, Thermodynamic analysis of binding between mouse major urinary protein-I and the pheromone 2-sec-butyl-4,5-dihydrothiazole, Biochemistry 42:6302–6309.

    Article  PubMed  CAS  Google Scholar 

  • Shevchenko, A., Sunyaev, S., Loboda, A., Shevchenko, A., Bork, P., Ens, W., and Standing, K.G., 2001, Charting the proteomes of organisms with unsequenced genomes by MALDI-quadrupole time-of-flight mass spectrometry and BLAST homology searching, Anal Chem. 73:1917–1926.

    Article  PubMed  CAS  Google Scholar 

  • Simpson, D. M., Beynon, R. J., Robertson, D. H. L., Loughran, M., and Haywood, S., 2004, Copper associated liver disease: a proteomics study of copper challenge in a sheep model, Proteomics 4 (in press).

    Google Scholar 

  • Singh, P. B., Brown, R. E., and Roser, B., 1987, MHC antigens in urine as olfactory recognition cues, Nature 327:161–164.

    Article  PubMed  CAS  Google Scholar 

  • Tegoni, M., Pelosi, P., Vincent, F., Spinelli, S., Campanacci, V., Grolli, S., Ramoni, R., and Cambillau, C., 2000, Mammalian odorant binding proteins, Biochim. Biophys. Acta. 1482:229–240.

    PubMed  CAS  Google Scholar 

  • Vandenbergh, J. G., Whitsett, J. M., and Lombardi, J. R., 1975, Partial isolation of a pheromone accelerating puberty in female mice, J. Reprod. Fert. 45:515–523.

    Article  Google Scholar 

  • Vandenberg, J. G., Finlayson, J. S., Dobrogosz, W. J., Dills, S. S., and Kost, T. A., 1976, Chromatographic separation of puberty accelerating pheromone from male mouse urine, Biol. Reprod. 15:260–265.

    Article  Google Scholar 

  • Zhang, W., and Chait, B. T., 2000, ProFound: an expert system for protein identification using mass spectrometric peptide mapping information, Anal. Chem. 72:2482–2489.

    Article  PubMed  CAS  Google Scholar 

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Robertson, D.H.L., Cheetham, S., Armstrong, S., Hurst, J.L., Beynon, R.J. (2005). Characterisation of proteins in scent marks: Proteomics meets semiochemistry. In: Mason, R.T., LeMaster, M.P., Müller-Schwarze, D. (eds) Chemical Signals in Vertebrates 10. Springer, Boston, MA . https://doi.org/10.1007/0-387-25160-X_23

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