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Functional Optical Coherence Tomography: Simultaneous in Vivo Imaging of Tissue Structure and Physiology

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Biophotonics

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4. Conclusions

OCT is a rapidly developing imaging technology with many potential applications. Through different contrast enhancement mechanisms, F-OCTprovides clinically important physiological information that is not available in the structure image. Integration of F-OCT, such as Doppler OCT, PS-OCT, spectroscopic OCT, and SH-OCT, can greatly enhance potential applications of this technology. Given the noninvasive nature and exceptionally high spatial resolution and velocity sensitivity, functional OCT that can simultaneously provide tissue structure, blood perfusion, birefringence, and other physiological information has great potential for basic biomedical research and clinical medicine.

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Author information

Authors and Affiliations

  1. Biomedical Engineering Beckman Laser Institute, University of California, Irvine Irvine, CA, 92612

    Zhongping Chen

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  1. Zhongping Chen
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Editor information

Editors and Affiliations

  1. Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

    Xun Shen

  2. Station Hombroich, International Institute of Biophysics, Neuss, Germany

    Roeland Van Wijk

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© 2005 Springer Science+Business Media, Inc.

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Chen, Z. (2005). Functional Optical Coherence Tomography: Simultaneous in Vivo Imaging of Tissue Structure and Physiology. In: Shen, X., Van Wijk, R. (eds) Biophotonics. Springer, Boston, MA . https://doi.org/10.1007/0-387-24996-6_5

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