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Molecular Basis of Calcium Regulation of Striated Muscle Contraction

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 565))

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References

  • Bailey, K., 1948, Tropomyosin: a new asymmetric protein component of the muscle fibril. Biochem. J. 43, 271–279.

    PubMed  CAS  Google Scholar 

  • Ebashi, S., 1974, Regulatory mechanism of muscle contraction with special reference to the Ca-troponin-tropomyosin system. Essays in Biochem. 10, 1–36.

    CAS  Google Scholar 

  • Ebashi, S., and Ebashi. F., 1964, Anew protein component participating in the superprecipitation of myosin B. J. Biochem. 55, 604–613.

    PubMed  CAS  Google Scholar 

  • Ebashi, S., and Kodama, A., 1965, A new protein factor promoting aggregation of tropomyosin. J. Biochem. 58, 107–108.

    PubMed  CAS  Google Scholar 

  • Ebashi, S., Endo, M., and Ohtsuki, I., 1969, Control of muscle contraction. Q. Rev. Biophys. 2, 351–384.

    Article  PubMed  CAS  Google Scholar 

  • Ebashi, S., Kodama, A., and Ebashi, F., 1968, Troponin 1. Preparation and physiological function. J. Biochem. 64, 465–477.

    PubMed  CAS  Google Scholar 

  • Fatkin, D. and Graham, R. M., 2002, Molecular mechanism of inherited cardiomyopathies. Physiol. Rev. 82, 945–980.

    PubMed  CAS  Google Scholar 

  • Flicker, P. F., Phillips, G.N., and Cohen, C., 1984, Structure of troponin and its interaction with tropomyosin; an eleotronmicroscope study. J. Mol. Biol. 162, 495–501.

    Article  Google Scholar 

  • Hatakenaka, M., and Ohtsuki, I., 1991, Replacement of three troponin components with cardiac troponin components within single glycerinated skeletal muscle fibers. Biochem. Biophys. Res. Commun. 181, 1022–1027.

    Article  PubMed  CAS  Google Scholar 

  • Hatakenaka, M., and Ohtsuki, I., 1992, Effect of removal and reconstitution of troponins C and I on the Ca2+-activated tension development of single glycerinated rabbit skeletal muscle fibers. Eur. J. Biochem. 205, 985–993.

    Article  PubMed  CAS  Google Scholar 

  • Kendrick-Jones, J., Lehman, W., and Szent-Györgyi, A. G., 1970, Regulation in molluscan muscles. J. Mol. Biol. 54, 313–326.

    Article  PubMed  CAS  Google Scholar 

  • Knollman, B. C., and Potter, J. D., 2001, Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy. Trends in Cardiovas. Med. 11,206–212.

    Article  Google Scholar 

  • Lu, Q-W., Morimoto, S., Harada, K., Du, C-K., Takahashi-Yanaga, F., Miwa, Y., Sasaguri, T., and Ohtsuki. I., 2003, Cardiac troponin T mutation found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes Ca2+ desensitization. J. Mol. Cell. Cardiol. 35, 1421–1427.

    Article  PubMed  CAS  Google Scholar 

  • Morgensen, J., Kubo, X, Duque, M., Uribe, W., Shaw, A., Murphy, R., J. R. Gimeno, J. R., Elliott, P., and Mckenna, W. J., 2003, Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations. J. Clin. Invest. 111, 209–216.

    Article  CAS  Google Scholar 

  • Morimoto, S., Yanaga, F., Minakami, R., and Ohtsuki, I., 1998, Ca2+-sensitizing effects of the mutations at Ile-79 and Arg-92 of troponin T in hypertrophic cardiomyopathy. Am. J. Physiol. 275, C200–C207.

    PubMed  CAS  Google Scholar 

  • Morimoto, S., Lu, Q-W., Harada, K., Takahashi-Yanaga, F., Minakami, R., Ohta, M., Sasaguri, T., and Ohtsuki, I., 2002, Ca2+desensitizing effect of a deletion mutation delta-K210 in cardiac troponin T that causes familial dilated cardiomyopathy. Proc. Natl. Acad. Sci. USA 99. 913–918 (2002)

    Article  PubMed  CAS  Google Scholar 

  • Nagano, K., and Ohtsuki, I., 1982, Prediction of approximate quarternary structure of troponin complex. Proc. Japan Acad. 58, Ser.B 73–77.

    CAS  Google Scholar 

  • Nakaura, H., Yanaga, F., Ohtsuki, I., and Morimoto, S., 1999, Effects of missense mutations PhellOIle and Glu244Asp in human cardiac troponin T on force generation in skinned cardiac muscle fibers. J. Biochem. 126, 457–460.

    PubMed  CAS  Google Scholar 

  • Ohtsuki, I., 1974, Localization of troponin in thin filament and tropomyosin paracrystal. J. Biochem. 75, 753–765.

    CAS  Google Scholar 

  • Ohtsuki, I., 1975, Distribution of troponin components in the thin filament studied by immunoelectron microscopy. J. Biochem. 77, 633–639.

    CAS  Google Scholar 

  • Ohtsuki, I., 1979, Molecular arrangement of troponin T in thin filament. J. Biochem. 86, 491–497.

    PubMed  CAS  Google Scholar 

  • Ohtsuki, I., 1980, Functional organization the troponin-tropomyosin system. In “Muscle contraction; its regulatory mechanisms (eds. S. Ebashi et al.)” pp237–250.

    Google Scholar 

  • Ohtsuki, I., 1995, Troponin components and calcium ion regulation of myofibrillar contraction in skeletal muscle. In “Calcium as Celt Signal” edited by K. Maruyama, Y, Nonomura, and K. Kohama (Igaku-shoin Tokyo · New York) pp. 36–42.

    Google Scholar 

  • Ohtsuki, I., and Nagano, K., 1982, Molecular arrangement of troponin-tropomyosin in the thin filament. Advances in Biophysics, 15, 93–130.

    Article  PubMed  CAS  Google Scholar 

  • Ohtsuki, I., and Shiraishi, F., 2002, Periodic binding of troponin C · I and troponin I to tropomyosin-actin filaments. J. Biochem. 131, 739–743.

    PubMed  CAS  Google Scholar 

  • Ohtsuki, I., Maruyama, K., and Ebashi, S., 1986, Regulatory and cytoskeletal proteins of vertebrate skeletal muscle. Adv. Prot. Chem. 38, 1–68.

    Article  CAS  Google Scholar 

  • Ohtsuki, I., Morimoto, S., and Takahashi-Yanaga, F., 2003, Several aspects of calcium regulatory mechanisms linked to troponin. Adv. Exp. Med. Biol. 538, 221–229.

    PubMed  CAS  Google Scholar 

  • Ohtsuki, I., Onoyama, Y., and Shiraishi, F., 1988, Electronmicroscopic study of troponin. J. Biochem. 103, 913–919.

    PubMed  CAS  Google Scholar 

  • Ohtsuki, I., Yamamoto, K., and Hashimoto, K., 1981, Effect of two C-terminal side chymotryptic subfragments on the Ca2+ sensitivity of superprecipitation and ATPase activities of actomyosin. J. Biochem. 90, 259–261.

    PubMed  CAS  Google Scholar 

  • Ohtsuki, I., Masaki, T., Nonomura, Y., and Ebashi, S., 1967, Periodic distribution of troponin along thin filament. J. Biochem. 81, 817–819.

    Google Scholar 

  • Ojima. T., and Nishita, K., 1986, Troponin from Akazara scallop striated adductor muscle. J. Biol. Chem. 261, 16749–16754.

    PubMed  CAS  Google Scholar 

  • Ojima, T., Koizumi, N., Ueyama, K., Inoue, A., and Nishita, K., 2000, Functional role of Ca2+-binding site IV of scallop troponin C, J. Biochem. 128, 803–809.

    PubMed  CAS  Google Scholar 

  • Perry, S. V., 1999, Troponin I: Inhibitor or facilitator. Mol. Cell. Biochem. 190, 9–32.

    Article  PubMed  CAS  Google Scholar 

  • Shiraishi, F., Kambara, M., and Ohtsuki, I., 1992, Replacement of troponin components in myofibrils, J. Biochem. 111. 61–65.

    PubMed  CAS  Google Scholar 

  • Shiraishi, F., Nakamura, Y., and Ohtsuki. I., 1993, Replacement of troponin in bullfrog skeletal myofibrils by rabbit skeletal and bovine cardiac troponins. Biomed. Res. 14(2), 93–97.

    CAS  Google Scholar 

  • Shiraishi, F., Morimoto, S., Nishita, K., Ojima, T., and Ohtsuki, I., 1999, Effects of removal and reconstitution of myosin regulatory light chain and troponin C on the Ca2+-sensitive ATPase activity of myofibrils from scallop striated muscle. J. Biochem. 126,1020–1024.

    PubMed  CAS  Google Scholar 

  • Szczesna, D., Zhang, R., Zhao, J., Jones, M., Guzman, G., and Potter. J. D., 2000, Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy. J. Biol. Chem. 275, 624–630.

    Article  PubMed  CAS  Google Scholar 

  • Szent-Györgyi, A. G., Kalabokis, V. N., and Perrealt-Micale, C. L., 1999, Regulation by molluscan myosins. Mol. Cell. Biochem. 190, 55–62.

    Article  PubMed  Google Scholar 

  • Takahashi-Yanaga, F., Morimoto, S., and Ohtsuki. I., 2000, Effect of Argl45Gly mutation in human cardiac troponin I found in familial hypertrophic cardiomyopathy. J. Biochem. 127, 355–357.

    PubMed  CAS  Google Scholar 

  • Takahashi-Yanaga, F., Morimoto, S., Harada, K., Minakami, R., Shiraishi, F., Ohta, M., Lu, Q-W., Sasaguri, T., and Ohtsuki, I., 2001, Functional consequences of the mutations in human cardiac troponin I gene found in familial hypertrophic cardiomyopathy. J. Mol. Cell. Cardiol. 33, 2095–2107.

    Article  PubMed  CAS  Google Scholar 

  • Takeda, S., Yamashita, A., Maeda, K., and Maeda, Y., 2003, Structure of the core domain of human cardiac troponin in the Ca2+-saturated form. Nature 424, 35–41.

    Article  PubMed  CAS  Google Scholar 

  • Tanokura, M., Tawada, Y., and Ohtsuki, I., 1982, Chymotryptic subfragments of troponin T from rabbit skeletal muscle. I. Determination of the primary structure. J. Biochem. 91,. 1257–1265.

    PubMed  CAS  Google Scholar 

  • Tanokura, M., Tawada, Y., Ono, A., and Ohtsuki, I., 1983, Chymotryptic subfragments of troponin T from rabbit skeletal muscle. Interaction with tropomyosin, troponin I and troponin C. J. Biochem. 93, 331–337.

    PubMed  CAS  Google Scholar 

  • Tobacman, L. S., Lin, D., Butters, C., Landis, C., Back, N., Pavlov, D., and Homsher, E., 1999, Functional consequences of troponin T mutations found in hypertrophic cardiomyopathy. J. Biol. Chem. 274, 28363–28370.

    Article  PubMed  CAS  Google Scholar 

  • Yanaga, F., Morimoto, S., and Ohtsuki, L., 1999, Ca2+ sensitization and potentiation of me maximum level of myofibrillar ATPase activity caused by mutations of troponin T found in familial hypertrophic cardiomyopathy. J. Biol. Chem. 274, 8806–8812.

    Article  PubMed  CAS  Google Scholar 

  • Yumoto, F., Nagata, K., Adachi, K., Nemoto, N., Ojima, T., Nishita, K., Ohtsuki, I., and Tanokura, M., 2003, NMR structural study of troponin C C-terminal domain complexed with troponin I fragment from Akazara scallop. Adv. Exp. Med. Biol. 538, 195–201.

    PubMed  CAS  Google Scholar 

  • Yumoto, F., Nara, M., Kagi, H.,. Iwasaki, W., Ojima, T., Nishita, K., Nagata, K., and Tanokura, M., 2001, Coordination structure of Ca2+ and Mg2+ in Akazara scallop troponin C in solution. FTIR spectroscopy of side-chain carboxy group. Eur. J. Biochem. 268. 6284–6290.

    Article  PubMed  CAS  Google Scholar 

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Ohtsuki, I. (2005). Molecular Basis of Calcium Regulation of Striated Muscle Contraction. In: Sugi, H. (eds) Sliding Filament Mechanism in Muscle Contraction. Advances in Experimental Medicine and Biology, vol 565. Springer, Boston, MA. https://doi.org/10.1007/0-387-24990-7_17

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  • DOI: https://doi.org/10.1007/0-387-24990-7_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-24989-6

  • Online ISBN: 978-0-387-24990-2

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